Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Regina D. Schnegelberger"'
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3756-3767 (2021)
Occupational and environmental exposures to industrial chemicals are well known to cause hepatotoxicity and liver injury. However, despite extensive evidence showing that exposure can lead to disease, current research approaches and regulatory polici
Externí odkaz:
https://doaj.org/article/0ac4da00042b4a3994cd2f3d10c6e7fd
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
OATP1B1 and OATP1B3 are two drug transporters that mediate the uptake of multiple endo- and xenobiotics, including many drugs, into human hepatocytes. Numerous inhibitors have been identified, and for some of them, it is not clear whether they are al
Externí odkaz:
https://doaj.org/article/c5d974ff976a4af2a5027a8f3317162a
Autor:
Silvia Liu, Liqing He, Olivia B. Bannister, Jiang Li, Regina D. Schnegelberger, Charis-Marie Vanderpuye, Andrew D. Althouse, Francisco J. Schopfer, Banrida Wahlang, Matthew C. Cave, Satdarshan P. Monga, Xiang Zhang, Gavin E. Arteel, Juliane I. Beier
Publikováno v:
Toxicology and Applied Pharmacology. 468:116514
Autor:
Silvia Liu, Liqing He, Olivia B Bannister, Regina D Schnegelberger, Junyan Tao, Andrew D Althouse, Francisco J Schopfer, Banrida Wahlang, Matthew C Cave, Satdarshan P Monga, Xiang Zhang, Gavin E Arteel, Juliane I Beier
Background & AimsVinyl chloride (VC) monomer is a volatile organic compound commonly used in industry to produce polyvinyl chloride (PVC). At high exposure levels, VC causes liver cancer and toxicant-associated steatohepatitis. However, lower exposur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6767ed4d262877d865eec064477791d4
https://doi.org/10.1101/2022.02.24.481808
https://doi.org/10.1101/2022.02.24.481808
Autor:
Erica F. Daly, Josiah E. Hardesty, Matthew C. Cave, Jian Jin, K. Cameron Falkner, Russell A. Prough, Banrida Wahlang, Irina A. Kirpich, Regina D. Schnegelberger, Juliane I. Beier
Publikováno v:
Curr Environ Health Rep
PURPOSE: Fatty liver disease (FLD) affects over 25% of the global population and may lead to liver-related mortality due to cirrhosis and liver cancer. FLD caused by occupational and environmental chemical exposures is termed ‘toxicant associated s
Autor:
Austin M. Krueger, Liya Chen, Anna L. Lang, Gavin E. Arteel, Maxwell J. Rakutt, Brenna R. Kaelin, Regina D. Schnegelberger, Juliane I. Beier
Publikováno v:
Toxicol Appl Pharmacol
Vinyl chloride (VC) is a prevalent environmental toxicant that is rapidly metabolized within the liver. Its metabolites have been shown to directly cause hepatic injury at high exposure levels. We have previously reported that VC metabolite, chloroet