Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Regina C. Armstrong"'
Publikováno v:
Neurotherapeutics, Vol 21, Iss 4, Pp e00410- (2024)
Externí odkaz:
https://doaj.org/article/f65e4f26c7d04a05b7bade2c50d3a20c
Autor:
Kryslaine L. Radomski, Xiaomei Zi, Fritz W. Lischka, Mark D. Noble, Zygmunt Galdzicki, Regina C. Armstrong
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-23 (2022)
Abstract Damage to long axons in white matter tracts is a major pathology in closed head traumatic brain injury (TBI). Acute TBI treatments are needed that protect against axon damage and promote recovery of axon function to prevent long term symptom
Externí odkaz:
https://doaj.org/article/438c351c4c2b4423af63b03c42c594af
Autor:
Donald V. Bradshaw, Andrew K. Knutsen, Alexandru Korotcov, Genevieve M. Sullivan, Kryslaine L. Radomski, Bernard J. Dardzinski, Xiaomei Zi, Dennis P. McDaniel, Regina C. Armstrong
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-19 (2021)
Abstract Traumatic brain injury (TBI) causes chronic symptoms and increased risk of neurodegeneration. Axons in white matter tracts, such as the corpus callosum (CC), are critical components of neural circuits and particularly vulnerable to TBI. Trea
Externí odkaz:
https://doaj.org/article/607f4770cd3745dfa35a929db9feece3
Autor:
Donald V. Bradshaw, Yeonho Kim, Amanda Fu, Christina M. Marion, Kryslaine L. Radomski, Joseph T. McCabe, Regina C. Armstrong
Publikováno v:
Neurotrauma Reports, Vol 2, Iss 1, Pp 180-192 (2021)
The potential effects of blast exposure on the brain health of military personnel have raised concerns and led to increased surveillance of blast exposures. Neuroimaging studies have reported white matter abnormalities in brains of service members wi
Externí odkaz:
https://doaj.org/article/fe14b47f97884b08a710d7467ea53eb0
Autor:
Genevieve M. Sullivan, Andrew K. Knutsen, Luca Peruzzotti-Jametti, Alexandru Korotcov, Asamoah Bosomtwi, Bernard J. Dardzinski, Joshua D. Bernstock, Sandra Rizzi, Frank Edenhofer, Stefano Pluchino, Regina C. Armstrong
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-23 (2020)
Abstract Multiple Sclerosis (MS) causes neurologic disability due to inflammation, demyelination, and neurodegeneration. Immunosuppressive treatments can modify the disease course but do not effectively promote remyelination or prevent long term neur
Externí odkaz:
https://doaj.org/article/599cef53dc3a4e46b2b4e66edd145f9c
Publikováno v:
Neurobiology of Disease, Vol 115, Iss , Pp 145-156 (2018)
Multiple sclerosis is a demyelinating disease in which neurological deficits result from damage to myelin, axons, and neuron cell bodies. Prolonged or repeated episodes of demyelination impair remyelination. We hypothesized that augmenting Sonic hedg
Externí odkaz:
https://doaj.org/article/f45e12ca9b214563a0bfad72c045e610
Publikováno v:
Stem Cells International, Vol 2017 (2017)
Neural stem cells (NSCs) delivered intraventricularly may be therapeutic for diffuse white matter pathology after traumatic brain injury (TBI). To test this concept, NSCs isolated from adult mouse subventricular zone (SVZ) were transplanted into the
Externí odkaz:
https://doaj.org/article/4247a5344a754f2f828342c93ae575d8
Publikováno v:
Neurobiology of Disease, Vol 45, Iss 1, Pp 196-205 (2012)
The adult mammalian brain contains multiple populations of endogenous progenitor cell types. However, following CNS trauma or disease, the regenerative capacity of progenitor populations is typically insufficient and may actually be limited by non-pe
Externí odkaz:
https://doaj.org/article/3a1d860301ca43898e8a755c140b3629
Publikováno v:
Neurobiology of Disease, Vol 19, Iss 1, Pp 171-182 (2005)
Repair of myelin damage in the adult CNS requires oligodendrocyte progenitor (OP) proliferation and subsequent differentiation into remyelinating oligodendrocytes. Platelet-derived growth factor (PDGF) and fibroblast growth factor-2 (FGF2) have been
Externí odkaz:
https://doaj.org/article/b6baf56e5f0e4645ac981f953452267c
Publikováno v:
ASN Neuro, Vol 6 (2014)
The regenerative capacity of the central nervous system must be optimized to promote repair following traumatic brain injury (TBI) and may differ with the site and form of damage. Sonic hedgehog (Shh) maintains neural stem cells and promotes oligoden
Externí odkaz:
https://doaj.org/article/582a95ffd1cf4051a75ed0c6632393d6