Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Regina Besoke"'
Autor:
Carsten Müller-Tidow, Wolfgang E. Berdel, Stefan Burdach, Heribert Jürgens, Daniel Baumhoer, Claudia Rossig, Eva Wardelmann, Wolfgang Hartmann, Gabriele Köhler, Monika Stoll, Anika Witten, Regina Besoke, Isabell Schulze, Matthias Weckesser, Thorsten Buch, Eberhard Korsching, Kathrin Poos, Martin Dugas, Udo Kontny, Hans-Ulrich Klein, Benjamin Moser, Kristina von Heyking, Uta Dirksen, Eva Schmidt, Günther H.S. Richter, Konstantin Agelopoulos
Supplementary Figures S1-6. Supplementary Fig S1: Combined patient characteristics and subjected methods Supplementary Fig. S2 A: ROC curves were constructed by using the somatic scores from the sequenced genotypes. Supplementary Fig. S3: Circos plot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e66069dde343fc00689de337b82a9f
https://doi.org/10.1158/1078-0432.22459203
https://doi.org/10.1158/1078-0432.22459203
Autor:
Carsten Müller-Tidow, Wolfgang E. Berdel, Stefan Burdach, Heribert Jürgens, Daniel Baumhoer, Claudia Rossig, Eva Wardelmann, Wolfgang Hartmann, Gabriele Köhler, Monika Stoll, Anika Witten, Regina Besoke, Isabell Schulze, Matthias Weckesser, Thorsten Buch, Eberhard Korsching, Kathrin Poos, Martin Dugas, Udo Kontny, Hans-Ulrich Klein, Benjamin Moser, Kristina von Heyking, Uta Dirksen, Eva Schmidt, Günther H.S. Richter, Konstantin Agelopoulos
Supplementary Materials. Additional Material and Methods section and clinical data of the Ponatib treated patient.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ac54f5bd1e6ce2e1cfd6c1992425a06
https://doi.org/10.1158/1078-0432.22459200
https://doi.org/10.1158/1078-0432.22459200
Autor:
Carsten Müller-Tidow, Wolfgang E. Berdel, Stefan Burdach, Heribert Jürgens, Daniel Baumhoer, Claudia Rossig, Eva Wardelmann, Wolfgang Hartmann, Gabriele Köhler, Monika Stoll, Anika Witten, Regina Besoke, Isabell Schulze, Matthias Weckesser, Thorsten Buch, Eberhard Korsching, Kathrin Poos, Martin Dugas, Udo Kontny, Hans-Ulrich Klein, Benjamin Moser, Kristina von Heyking, Uta Dirksen, Eva Schmidt, Günther H.S. Richter, Konstantin Agelopoulos
Purpose: A low mutation rate seems to be a general feature of pediatric cancers, in particular in oncofusion gene-driven tumors. Genetically, Ewing sarcoma is defined by balanced chromosomal EWS/ETS translocations, which give rise to oncogenic chimer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab9955f34fc024c4c397cbadc4c48654
https://doi.org/10.1158/1078-0432.c.6524157.v1
https://doi.org/10.1158/1078-0432.c.6524157.v1
Autor:
Carsten Müller-Tidow, Wolfgang E. Berdel, Stefan Burdach, Heribert Jürgens, Daniel Baumhoer, Claudia Rossig, Eva Wardelmann, Wolfgang Hartmann, Gabriele Köhler, Monika Stoll, Anika Witten, Regina Besoke, Isabell Schulze, Matthias Weckesser, Thorsten Buch, Eberhard Korsching, Kathrin Poos, Martin Dugas, Udo Kontny, Hans-Ulrich Klein, Benjamin Moser, Kristina von Heyking, Uta Dirksen, Eva Schmidt, Günther H.S. Richter, Konstantin Agelopoulos
Supplementary Tables S1-6. Table S1: Validation of somatic mutations by Sanger sequencing for construction of ROC Table S2: Characteristics of the discovery data set for exome sequencing Table S3: Somatic mutations in the discovery data set (filtered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84d11955cccbf221f514772713b440c3
https://doi.org/10.1158/1078-0432.22459197
https://doi.org/10.1158/1078-0432.22459197
Autor:
Carsten Müller-Tidow, Eberhard Korsching, Daniel Baumhoer, Anika Witten, Udo Kontny, Kristina von Heyking, Regina Besoke, Hans-Ulrich Klein, Martin Dugas, Heribert Jürgens, Matthias Weckesser, Wolfgang E. Berdel, Stefan Burdach, Konstantin Agelopoulos, Günther H.S. Richter, Gabriele Köhler, Wolfgang Hartmann, Uta Dirksen, Eva Schmidt, Thorsten Buch, Monika Stoll, Isabell Schulze, Claudia Rossig, Eva Wardelmann, Kathrin Poos, Benjamin Moser
Purpose: A low mutation rate seems to be a general feature of pediatric cancers, in particular in oncofusion gene-driven tumors. Genetically, Ewing sarcoma is defined by balanced chromosomal EWS/ETS translocations, which give rise to oncogenic chimer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce502a215d8faccc8b1219d8a72d95d
https://www.zora.uzh.ch/id/eprint/123050/
https://www.zora.uzh.ch/id/eprint/123050/
Autor:
Rainer Bald, Regina Besoke, Benjamin Joseph, Hitesh Shah, Christian Kähler, Karsten Held, Sabine Lüttgen, Ingo Kurth, Eva Klopocki, Stefan Mundlos, Nicola Foulds, Hermann Vogel
Publikováno v:
European journal og human genetics : EJHG ; the official journal of the European Society of Human Genetics
PITX1 is a bicoid-related homeodomain transcription factor implicated in vertebrate hindlimb development. Recently, mutations in PITX1 have been associated with autosomal-dominant clubfoot. In addition, one affected individual showed a polydactyly an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7404e8234cfcbbc4d549e5c4dbc3dcb
https://hdl.handle.net/11858/00-001M-0000-000E-F26C-911858/00-001M-0000-000E-F389-0
https://hdl.handle.net/11858/00-001M-0000-000E-F26C-911858/00-001M-0000-000E-F389-0