Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Regina Berg"'
Autor:
Regina Berg, Bernd F. Straub
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 9, Iss 1, Pp 2715-2750 (2013)
The copper-catalyzed azide–alkyne cycloaddition (CuAAC) is one of the most broadly applicable and easy-to-handle reactions in the arsenal of organic chemistry. However, the mechanistic understanding of this reaction has lagged behind the plethora o
Externí odkaz:
https://doaj.org/article/b17f4c24a66b43c3bd75742b1ded7b9c
Autor:
Daniel Schäfle, Andrea Dorst, Peter Sander, Christoph G. W. Gertzen, Holger Gohlke, Karl Gademann, Regina Berg, Simon D. Schnell, Myriam Gwerder, Katja Zerbe
Publikováno v:
ACS medicinal chemistry letters 11(12), 2414–2420 (2020). doi:10.1021/acsmedchemlett.0c00381
ACS Medicinal Chemistry Letters
ACS Medicinal Chemistry Letters
The glycoslated macrocyclic antibiotic fidaxomicin (1, tiacumicin B, lipiarmycin A3) displays good to excellent activity against Gram-positive bacteria and was approved for the treatment of Clostridium difficile infections (CDI). Among the main limit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c95d35ed8d9b436ed029d5994f86bec
https://doi.org/10.1021/acsmedchemlett.0c00381
https://doi.org/10.1021/acsmedchemlett.0c00381
Autor:
Simon D. Schnell, Peter Sander, Andrea Dorst, Holger Gohlke, Katja Zerbe, Daniel Schäfle, Myriam Gwerder, Karl Gademann, Christoph G. W. Gertzen, Regina Berg
The glycoslated macrocyclic antibiotic fidaxomicin (1, tiacumicin B, lipiarmycin A3) displays good to excellent activity against Gram-positive bacteria and was approved for the treatment of Clostridium difficile infections (CDI). Main limitations of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32e6048b3ba68b064e6e8962bfde5c09
https://doi.org/10.26434/chemrxiv.12613823.v1
https://doi.org/10.26434/chemrxiv.12613823.v1
Publikováno v:
The Journal of Organic Chemistry. 83:604-613
The Cu-free 1,3-dipolar cycloaddition of cyclooctynes and azides is an up-and-coming method in bioorganic chemistry and other disciplines. However, broad application is still hampered by major drawbacks such as poor solubility of the reactants in aqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e83e856577e9fdd17b40b222058de404
https://doi.org/10.1021/acs.joc.7b02092
https://doi.org/10.1021/acs.joc.7b02092
Autor:
Andrea Chicca, Jürg Gertsch, Nicolas Marck, Patrick Burch, Karl Gademann, Henning J. Jessen, Regina Berg, Fabian Schmid
Publikováno v:
Bioorganic & Medicinal Chemistry. 25:6102-6114
Naturally occurring pyridone alkaloids as well as synthetic derivatives were previously shown to induce neurite outgrowth. However, the molecular basis for this biological effect remains poorly understood. In this work, we have prepared new pyridones
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7c02080dec8eec4e665e9a3e9c539d3
https://doi.org/10.1016/j.bmc.2017.02.031
https://doi.org/10.1016/j.bmc.2017.02.031
Autor:
Regina Berg
Bachelorarbeit aus dem Jahr 2020 im Fachbereich Medizin - Chirurgie, Unfallmedizin, Note: 1,3,, Sprache: Deutsch, Abstract: Die operative Versorgung von Leistenhernien ist mit mehr als 20 Millionen Betroffenen im Jahr eine der am meisten durchgeführ
Publikováno v:
The Journal of organic chemistry. 83(13)
The commercial macrolide antibiotic fidaxomicin was synthesized in a highly convergent manner. Salient features of this synthesis include a β-selective noviosylation, a β-selective rhamnosylation, a ring-closing metathesis, a Suzuki coupling, and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d168690a43dda75c2fd130c524f1de19
https://pubmed.ncbi.nlm.nih.gov/29590752
https://pubmed.ncbi.nlm.nih.gov/29590752
Publikováno v:
Angewandte Chemie. 127:7539-7543
Ein molekular definierter Kupferacetylidcluster mit N-heterocyclischen Carben-Steuerliganden (NHC) wurde zum ersten Mal unter sauren Reaktionsbedingungen hergestellt. Dieser Cluster ist der erste molekulare Kupferacetylid-Komplex, der eine hohe Aktiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23f7192e19a07c20e7418b52f384d54a
https://doi.org/10.1002/ange.201502368
https://doi.org/10.1002/ange.201502368
Publikováno v:
Health Science Reports, Vol 6, Iss 12, Pp n/a-n/a (2023)
Abstract Background and Aims Involving patients in research, not only as trial subjects, is not a newly established practice. Over the last two decades, patient roles have gradually expanded to become active research contributors, creating a more pat
Externí odkaz:
https://doaj.org/article/d965620ee076491e838c3c341c9dec70
Autor:
Regina Bergmann
Publikováno v:
Linguistische Treffen in Wrocław, Iss 22, Pp 17-31 (2023)
Using the example of a lecture hall occupation, the question of the extent to which interaction and space are related is investigated. Space is described as a construct that is assigned certain usage options on the basis of institutional specificatio
Externí odkaz:
https://doaj.org/article/f1fd3122508f493eaa650fd88939f55c