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pro vyhledávání: '"Regina Baur"'
Publikováno v:
eLife, Vol 7 (2018)
Metazoan development depends on tightly regulated gene expression programs that instruct progenitor cells to adopt specialized fates. Recent work found that posttranslational modifications, such as monoubiquitylation, can determine cell fate also ind
Externí odkaz:
https://doaj.org/article/1faa5242a6dd4e2293637090dd94a44c
Autor:
Michael Rape, Regina Baur
Publikováno v:
Structure. 28:1-3
K11/K48-branched ubiquitin chains are proteasomal priority signals that elicit the rapid elimination of mitotic regulators and aggregation-prone proteins. Indicative of an intriguing signaling mode, Boughton et al. (2019) unravel an interaction betwe
Autor:
Eva M. Huber, Michael Groll, Haissi Cui, Regina Baur, Camille Le Chapelain, Christian Dubiella, Wolfgang Heinemeyer
Publikováno v:
ChemBioChem. 18:523-526
Selective inhibition of the immunoproteasome is a promising approach towards the development of immunomodulatory drugs. Recently, a class of substituted thiazole compounds that combine a non-peptidic scaffold with the absence of an electrophile has b
Publikováno v:
Angewandte Chemie. 127:16116-16120
Publikováno v:
eLife
eLife, Vol 7 (2018)
eLife, Vol 7 (2018)
Metazoan development depends on tightly regulated gene expression programs that instruct progenitor cells to adopt specialized fates. Recent work found that posttranslational modifications, such as monoubiquitylation, can determine cell fate also ind
Autor:
Francilina Araújo Costa, Cristiano Marcelo Espinola Carvalho, Celia de Fátima Menegati, Josimara Nolasco Rondon, Pricila Fatima de Souza, Claudia Regina Baur Arfux, Renata Moreira da Silva, Cristiane Bezerra da Silva, Valdinez Gabriel
Publikováno v:
Revista Eletrônica em Gestão, Educação e Tecnologia Ambiental. :1555-1560
A chia (Salvia hispanica L.) é uma planta herbácea anual originária do México que em tempos pré colombianos foi muito utilizada com finalidade alimentar e medicinal, mas durante o processo de domesticação sofreu perda de habitat devido a degra
Publikováno v:
Angewandte Chemie (International ed. in English). 54(52)
Clinically applied proteasome inhibitors induce cell death by concomitant blockage of constitutive and immunoproteasomes. In contrast, selective immunoproteasome inhibition is less cytotoxic and has the potential to modulate chronic inflammation and