Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Regina, Leidolf"'
Autor:
Daniela Nürnberger, Lisa Wagner, Simon F. Müller, Silke Leiting, Regina Leidolf, Jörg Alber, Melanie Hamann, Joachim Geyer
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2022)
The multidrug resistance gene MDR1 (syn. ABCB1) encodes for the multidrug efflux transporter P-glycoprotein (P-gp), which is highly expressed at the blood-brain barrier and protects the brain from potentially neurotoxic compounds, such as ivermectin.
Externí odkaz:
https://doaj.org/article/de1d65f8c79943919d009c7016cf2e90
Autor:
Dorothea Leonhäuser, Jasmin Kranz, Regina Leidolf, Patrick Arndt, Ulrich Schwantes, Joachim Geyer, Joachim O. Grosse
Publikováno v:
BMC Urology, Vol 19, Iss 1, Pp 1-8 (2019)
Abstract Background Porcine urinary bladders are widely used for uro-pharmacological examinations due to their resemblance to the human organ. However, characterisations of the porcine urothelium at the molecular level are scarce up to now. As it has
Externí odkaz:
https://doaj.org/article/52540affa9a043f596d36e8bc81e1238
Autor:
Dariusz Zakrzewicz, Regina Leidolf, Sebastian Kunz, Simon Franz Müller, Anita Neubauer, Silke Leiting, Nora Goldmann, Felix Lehmann, Dieter Glebe, Joachim Geyer
Publikováno v:
Viruses, Vol 14, Iss 6, p 1259 (2022)
Na+/taurocholate cotransporting polypeptide (NTCP, gene symbol SLC10A1) is a hepatic bile acid uptake carrier participating in the enterohepatic circulation of bile acids. Apart from its transporter function, NTCP acts as the high-affinity liver-spec
Externí odkaz:
https://doaj.org/article/f1e02be73de54cefa79e776777a2a09a
Autor:
Emre Karakus, Daniel Zahner, Gary Grosser, Regina Leidolf, Cemal Gundogdu, Alberto Sánchez-Guijo, Stefan A. Wudy, Joachim Geyer
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Estrogens play a pivotal role in the development and proliferation of hormone-dependent breast cancer. Apart from free estrogens, which can directly activate the estrogen receptor (ER) of tumor cells, sulfo-conjugated steroids, which maintain high pl
Externí odkaz:
https://doaj.org/article/02c02b5c18604a249c0adfa47d0f8aa8
Autor:
Emre, Karakus, Marie, Wannowius, Simon Franz, Müller, Silke, Leiting, Regina, Leidolf, Saskia, Noppes, Stefan, Oswald, Martin, Diener, Joachim, Geyer
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
SLC10A7 represents an orphan member of the Solute Carrier Family SLC10. Recently, mutations in the human SLC10A7 gene were associated with skeletal dysplasia, amelogenesis imperfecta, and decreased bone mineral density. However, the exact molecular f
Autor:
Daniela, Nürnberger, Lisa, Wagner, Simon F, Müller, Silke, Leiting, Regina, Leidolf, Jörg, Alber, Melanie, Hamann, Joachim, Geyer
Publikováno v:
Frontiers in veterinary science. 8
The multidrug resistance gene MDR1 (syn. ABCB1) encodes for the multidrug efflux transporter P-glycoprotein (P-gp), which is highly expressed at the blood-brain barrier and protects the brain from potentially neurotoxic compounds, such as ivermectin.
Autor:
Matthias Holtemeyer, J. Alber, Regina Leidolf, Simon Franz Müller, Joachim Geyer, Josefine Bennien, Massimo Palatini, Saskia Noppes
Publikováno v:
Biological Chemistry. 400:1371-1384
The solute carrier family SLC10 consists of seven members, including the bile acid transporters Na+/taurocholate co-transporting polypeptide (NTCP) and apical sodium-dependent bile acid transporter (ASBT), the steroid sulfate transporter SOAT as well
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 1
International Journal of Molecular Sciences, Vol 22, Iss 22, p 22 (2021)
Volume 22
Issue 1
International Journal of Molecular Sciences, Vol 22, Iss 22, p 22 (2021)
Background: The muscarinic receptor antagonist trospium chloride (TCl) is used for pharmacotherapy of the overactive bladder syndrome. TCl is a hydrophilic positively charged drug. Therefore, it has low permeability through biomembranes and requires
Autor:
Regina Leidolf, Jasmin Kranz, Joachim Grosse, Dorothea Leonhäuser, Patrick Arndt, Ulrich Schwantes, Joachim Geyer
Publikováno v:
BMC Urology, Vol 19, Iss 1, Pp 1-8 (2019)
BMC urology 19(1), 62 (2019). doi:10.1186/s12894-019-0495-z
BMC Urology
BMC urology 19(1), 62 (2019). doi:10.1186/s12894-019-0495-z
BMC Urology
BMC urology 19(1), 62 (2019). doi:10.1186/s12894-019-0495-z
Published by BioMed Central, London
Published by BioMed Central, London
Autor:
Ebru Yalçin, Ernst Petzinger, Irina Gramer, Joachim Geyer, Eva-Maria Krämer, Stefanie Klintzsch, Barbara Döring, Regina Leidolf
Publikováno v:
The Veterinary Journal. 189:67-71
A 4-bp deletion mutation associated with multiple drug sensitivity exists in the canine multidrug resistance (MDR1) gene. This mutation has been detected in more than 10 purebred dog breeds as well as in mixed breed dogs. To evaluate the breed distri