Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Regina, Leber"'
Autor:
Christina Wodlej, Sabrina Riedl, Beate Rinner, Regina Leber, Carina Drechsler, Dennis R Voelker, Jae-Yeon Choi, Karl Lohner, Dagmar Zweytick
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0211187 (2019)
R-DIM-P-LF11-322 and DIM-LF11-318, derived from the cationic human host defense peptide lactoferricin show antitumor activity against human melanoma. While R-DIM-P-LF11-322 interacts specifically with cancer cells, the non-specific DIM-LF11-318 exhib
Externí odkaz:
https://doaj.org/article/d41f7d6a7a7542fd95a2a9bdcd0d92aa
Publikováno v:
Biochimica et biophysica acta. Biomembranes. 1862(8)
The aim of this study was to develop effective and specific anti-cancer drugs based on membrane active peptides. In previous studies we showed that human lactoferricin (hLFcin) derived peptides facilitate specific killing of cancer cells. These antit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af324a7168727d7ec93c2d3a5e5f510d
https://pubmed.ncbi.nlm.nih.gov/32151609
https://pubmed.ncbi.nlm.nih.gov/32151609
Autor:
Regina, Leber, Michael, Pachler, Ivo, Kabelka, Irene, Svoboda, Daniel, Enkoller, Robert, Vácha, Karl, Lohner, Georg, Pabst
Publikováno v:
Biophysical Journal
Mixtures of the frog peptides magainin 2 and PGLa are well-known for their pronounced synergistic killing of Gram-negative bacteria. We aimed to gain insight into the underlying biophysical mechanism by interrogating the permeabilizing efficacies of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::819201a211ffeb70f7aaccbf68d0c542
https://pubmed.ncbi.nlm.nih.gov/29694871
https://pubmed.ncbi.nlm.nih.gov/29694871
Autor:
Ivo Kabelka, Karl Lohner, Ilse Letofsky-Papst, Georg Pabst, Regina Leber, Robert Vácha, Michael Pachler
Publikováno v:
Biophysical Journal. 116:44a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3ce2bdb2eb129639fc6dc1bed78fdb1
https://doi.org/10.1016/j.bpj.2018.11.280
https://doi.org/10.1016/j.bpj.2018.11.280
Autor:
Regina Leber, Karl Lohner
Publikováno v:
Host Defense Peptides and Their Potential as Therapeutic Agents ISBN: 9783319329475
Fungi infect billions of people every year, yet their contribution to the global burden of disease is largely unrecognized and the repertoire of antifungal agents is rather limited. Thus, treatment of life-threatening invasive fungal infections is st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67c42b92141833e78f377e3336fa3a6d
https://doi.org/10.1007/978-3-319-32949-9_2
https://doi.org/10.1007/978-3-319-32949-9_2
Autor:
Helmut Schwab, Giuliano Freddi, Ruth Birner-Gruenberger, Georg M. Guebitz, Thomas Weber, Ilaria Donelli, Sigrid Deller, Karl-Heinz Maurer, Regina Leber, Peter Remler, Inge Eiteljoerg, Petra Siegert, Enrique Herrero Acero, Sonja Heumann, Katrin Greimel, Eva Trotscha, Doris Ribitsch
Publikováno v:
Biotechnology Progress. 27:951-960
From a screening on agar plates with bis(benzoyloxyethyl) terephthalate (3PET), a Bacillus subtilis p-nitrobenzylesterase (BsEstB) was isolated and demonstrated to hydrolyze polyethyleneterephthalate (PET). PET-hydrolase active strains produced clear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f5c7b33624769c814c61e06d0d6b94b
https://doi.org/10.1002/btpr.610
https://doi.org/10.1002/btpr.610
Autor:
Jan W. Drijfhout, Peter H. Nibbering, Karl Lohner, Nermina Malanovic, Anna de Breij, Regina Leber, Maria Schmuck, Manfred Kriechbaum, Robert A. Cordfunke, Dagmar Kolb
Publikováno v:
BBA-Biomembranes, 1848(10), 2437-2447
BBA-Biomembranes
BBA-Biomembranes
OP-145, a synthetic antimicrobial peptide developed from a screen of the human cathelicidin LL-37, displays strong antibacterial activities and is — at considerably higher concentrations — lytic to human cells. To obtain more insight into its act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71ff848c8e227320f36cd8559962e806
http://hdl.handle.net/1887/104333
http://hdl.handle.net/1887/104333
Autor:
Sabrina, Riedl, Regina, Leber, Beate, Rinner, Helmut, Schaider, Karl, Lohner, Dagmar, Zweytick
Publikováno v:
Biochimica et biophysica acta. 1848(11 Pt)
Host defense-derived peptides have emerged as a novel strategy for the development of alternative anticancer therapies. In this study we report on characteristic features of human lactoferricin (hLFcin) derivatives which facilitate specific killing o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4d5aff99be26296adbd342a7fbf5ea3d
https://pubmed.ncbi.nlm.nih.gov/26239537
https://pubmed.ncbi.nlm.nih.gov/26239537
Autor:
Klaus Natter, Harald Scholz, Kim Scheuringer, Robert Zimmermann, Heimo Wolinski, Sepp D. Kohlwein, Regina Leber, Christoph F. Kurat, Julia Petschnigg, Rudolf Zechner
Publikováno v:
Journal of Biological Chemistry. 281:491-500
Storage and degradation of triglycerides are essential processes to ensure energy homeostasis and availability of precursors for membrane lipid synthesis. Recent evidence suggests that an emerging class of enzymes containing a conserved patatin domai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20402603f1966fcf4610be1214b2fb62
https://doi.org/10.1074/jbc.m508414200
https://doi.org/10.1074/jbc.m508414200
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1663(1-2):9-13
In the yeast Saccharomyces cerevisiae, three enzymes of the sterol biosynthetic pathway, namely Erg1p, Erg6p and Erg7p, are located in lipid particles. Whereas Erg1p (squalene epoxidase) is also present in the endoplasmic reticulum (ER) to a signific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a4383eba7402868be7f07b264973d7