Initial results from the New Horizons exploration of 2014 MU69, a small Kuiper Belt Object

Autor: Stern, S. A., Weaver, H. A., Spencer, J. R., Olkin, C. B., Gladstone, G. R., Grundy, W. M., Moore, J. M., Cruikshank, D. P., Elliott, H. A., McKinnon, W. B., Parker, J. Wm., Verbiscer, A. J., Young, L. A., Aguilar, D. A., Albers, J. M., Andert, T., Andrews, J. P., Bagenal, F., Banks, M. E., Bauer, B. A., Bauman, J. A., Bechtold, K. E., Beddingfield, C. B., Behrooz, N., Beisser, K. B., Benecchi, S. D., Bernardoni, E., Beyer, R. A., Bhaskaran, S., Bierson, C. J., Binzel, R. P., Birath, E. M., Bird, M. K., Boone, D. R., Bowman, A. F., Bray, V. J., Britt, D. T., Brown, L. E., Buckley, M. R., Buie, M. W., Buratti, B. J., Burke, L. M., Bushman, S. S., Carcich, B., Chaikin, A. L., Chavez, C. L., Cheng, A. F., Colwell, E. J., Conard, S. J., Conner, M. P., Conrad, C. A., Cook, J. C., Cooper, S. B., Custodio, O. S., Ore, C. M. Dalle, Deboy, C. C., Dharmavaram, P., Dhingra, R. D., Dunn, G. F., Earle, A. M., Egan, A. F., Eisig, J., El-Maarry, M. R., Engelbrecht, C., Enke, B. L., Ercol, C. J., Fattig, E. D., Ferrell, C. L., Finley, T. J., Firer, J., Fischetti, J., Folkner, W. M., Fosbury, M. N., Fountain, G. H., Freeze, J. M., Gabasova, L., Glaze, L. S., Green, J. L., Griffith, G. A., Guo, Y., Hahn, M., Hals, D. W., Hamilton, D. P., Hamilton, S. A., Hanley, J. J., Harch, A., Harmon, K. A., Hart, H. M., Hayes, J., Hersman, C. B., Hill, M. E., Hill, T. A., Hofgartner, J. D., Holdridge, M. E., Horányi, M., Hosadurga, A., Howard, A. D., Howett, C. J. A., Jaskulek, S. E., Jennings, D. E., Jensen, J. R., Jones, M. R., Kang, H. K., Katz, D. J., Kaufmann, D. E., Kavelaars, J. J., Keane, J. T., Keleher, G. P., Kinczyk, M., Kochte, M. C., Kollmann, P., Krimigis, S. M., Kruizinga, G. L., Kusnierkiewicz, D. Y., Lahr, M. S., Lauer, T. R., Lawrence, G. B., Lee, J. E., Lessac-Chenen, E. J., Linscott, I. R., Lisse, C. M., Lunsford, A. W., Mages, D. M., Mallder, V. A., Martin, N. P., May, B. H., McComas, D. J., McNutt, R. L., Mehoke, Jr. D. S., Mehoke, T. S., Nelson, D. S., Nguyen, H. D., Núñez, J. I., Ocampo, A. C., Owen, W. M., Oxton, G. K., Parker, A. H., Pätzold, M., Pelgrift, J. Y., Pelletier, F. J., Pineau, J. P., Piquette, M. R., Porter, S. B., Protopapa, S., Quirico, E., Redfern, J. A., Regiec, A. L., Reitsema, H. J., Reuter, D. C., Richardson, D. C., Riedel, J. E., Ritterbush, M. A., Robbins, S. J., Rodgers, D. J., Rogers, G. D., Rose, D. M., Rosendall, P. E., Runyon, K. D., Ryschkewitsch, M. G., Saina, M. M., Salinas, M. J., Schenk, P. M., Scherrer, J. R., Schlei, W. R., Schmitt, B., Schultz, D. J., Schurr, D. C., Scipioni, F., Sepan, R. L., Shelton, R. G., Showalter, M. R., Simon, M., Singer, K. N., Stahlheber, E. W., Stanbridge, D. R., Stansberry, J. A., Steffl, A. J., Strobel, D. F., Stothoff, M. M., Stryk, T., Stuart, J. R., Summers, M. E., Tapley, M. B., Taylor, A., Taylor, H. W., Tedford, R. M., Throop, H. B., Turner, L. S., Umurhan, O. M., Van Eck, J., Velez, D., Versteeg, M. H., Vincent, M. A., Webbert, R. W., Weidner, S. E., Weigle II, G. E., Wendel, J. R., White, O. L., Whittenburg, K. E., Williams, B. G., Williams, K. E., Williams, S. P., Winters, H. L., Zangari, A. M., Zurbuchen, T. H.

Publikováno v: Science 364, eaaw9771 (2019)

The Kuiper Belt is a distant region of the Solar System. On 1 January 2019, the New Horizons spacecraft flew close to (486958) 2014 MU69, a Cold Classical Kuiper Belt Object, a class of objects that have never been heated by the Sun and are therefore

Externí odkaz: http://arxiv.org/abs/2004.01017

EVALUATION OF ANTIBACTERIAL ACTIVITY 5-AMINO-3-METHYLISOXAZOLE-4-CARBOHYDRAZIDE AND 5-AMINOISOXAZOLE[5,4-d]PYRIMIDIN-4-ONE DERIVATIVES

Autor: Marcin Mączyński, Andrzej Regiec, Paulina Płoszaj, Miroslawa Kacaniova, Agnieszka Piwowar

Publikováno v: Acta Poloniae Pharmaceutica, Vol 80, Iss 1, Pp 79-90 (2023)

Searching for new compounds with specific biological activity in relation to various bacterial strains due to the increasing number of bacterial infections and the frequently developing antimicrobial resistance (AMR) is a significant problem in healt

Externí odkaz: https://doaj.org/article/b5948ebe55fd480ab6b5ae2c62ca1430

FDA-Approved Small Molecule Compounds as Drugs for Solid Cancers from Early 2011 to the End of 2021

Autor: Aleksandra Sochacka-Ćwikła, Marcin Mączyński, Andrzej Regiec

Publikováno v: Molecules, Vol 27, Iss 7, p 2259 (2022)

Solid cancers are the most common types of cancers diagnosed globally and comprise a large number of deaths each year. The main challenge currently in drug development for tumors raised from solid organs is to find more selective compounds, which exp

Externí odkaz: https://doaj.org/article/0de3643aa09a4fb19df9a0592be2bddb

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Synthesis and Biological Activity of New 7-Amino-oxazolo[5,4-d]Pyrimidine Derivatives

Autor: Aleksandra Sochacka-Ćwikła, Andrzej Regiec, Michał Zimecki, Jolanta Artym, Ewa Zaczyńska, Maja Kocięba, Iwona Kochanowska, Iwona Bryndal, Anna Pyra, Marcin Mączyński

Publikováno v: Molecules, Vol 25, Iss 15, p 3558 (2020)

The synthesis of a series of novel 7-aminooxazolo[5,4-d]pyrimidines 5, transformations during their synthesis and their physicochemical characteristics have been described. Complete detailed spectral analysis of the intermediates 2–4, the N′-cyan

Externí odkaz: https://doaj.org/article/a9af095ab48a4abe927954a408517e3a