Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Regenerative Medicine (incl. Stem Cells and Tissue Engineering)"'
Autor:
Brady, Robert Thomas
Osteoporosis is the most prevalent bone disease and represents a major public health burden. Resulting from a reduction in bone quality and quantity, it can lead to fragility fractures with significant associated morbidity and mortality. Mechanical l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::483c2f6ad4768dc1f6b9423efc29eff7
Autor:
Soriano, Luis
Respiratory diseases and major airway trauma represent a global healthcare emergency with most treatment options providing symptomatic relief rather than curative treatment. In addition, they are associated with enormous socioeconomic burden. Respira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82b3c5e42d82dda58e48c31743aaa901
Autor:
Intini, Claudio
This thesis has led to the development of a novel highly porous collagen-based scaffold for enhanced and longer lasting cartilage repair, by incorporating type II collagen (CII) and hyaluronic acid (HyA) within a type I collagen (CI) framework. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::149fee317f404476bf715429ae810742
Autor:
Paige Hinton (7896950)
Osteoarthritis (OA) is the most common musculoskeletal disease in the western world and treatment options are currently limited. Post-traumatic osteoarthritis (PTOA) is a common subtype of the broader age-related/idiopathic OA, and results from acute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3591785778c74771da71231e8343dabf
Autor:
Lemoine, Mark
Articular cartilage has limited self-healing capacity and damaged cartilage can lead to osteoarthritis, and to the need for joint replacement surgery. Biomaterial based scaffolds have shown limited potential to regenerate osteochondral tissue and gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bbc003fa3372d9ab0474f0f27056b51
Autor:
Santarella, Francesco
Diabetic foot ulcers (DFU) are highly prevalent amongst diabetics (60 M) and a major economic burden (760 billion USD). DFU are chronic wounds refractory to surgical debridement and therapeutic dressings, with15-20% of cases requiring limb amputation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4751ef5881c30359e00df07498f6970f
Autor:
Sirafim, Catherine
The body naturally orchestrates response to injuries by producing a variety of bioactive cues at precisely coordinated times. However, when this response is hindered –as it is in many diseased states –this results in a lack of healing. Localised
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::070b6290f7ad5039c2be2dd5aa3f3438
Autor:
ANISHA BALACHANDRAN SURAIYA
T cells are an essential arm of the adaptive immune system and are also harnessed as therapeutic agents for cancer immunotherapy. This thesis has focussed on the development of bioengineered 3-dimensional (3D) hydrogel microenvironments to address so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ba6326ff8a7afbd7cd77c1cdd84d1eb
This report provides an overview of the ethical, legal, social, political and economic (ELSPE) issues underpinning the “manufacturing, business and regulatory challenges” that confront the development and delivery of affordable and accessible new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd57d23c280bda0ea44100dc68334417
Autor:
DONDERWINKEL, ILZE
This thesis developed a model to study the development of a bone-tendon interface. It identified key players for the generation of an engineered bone-tendon interface that in the future can assist in the clinic for tendon injuries.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8495ada356a26f141e10c19d2fbdff55