Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Regan Roat"'
Autor:
Md Munir Hossain, Regan Roat, Jenica Christopherson, Colette Free, Ansarullah, Brian James, Zhiguang Guo
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundLong noncoding RNA (lncRNA)-mediated posttranscriptional and epigenetic landscapes of gene regulation are associated with numerous human diseases. However, the regulatory mechanisms governing human β-cell function and survival remain unkno
Externí odkaz:
https://doaj.org/article/f32ee2860de5411887f6fa5560a123fb
Autor:
Regan Roat, Vandana Rao, Nicolai M Doliba, Franz M Matschinsky, John W Tobias, Eden Garcia, Rexford S Ahima, Yumi Imai
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e86815 (2014)
The reduction of functional β cell mass is a key feature of type 2 diabetes. Here, we studied metabolic functions and islet gene expression profiles of C57BL/6J mice with naturally occurring nicotinamide nucleotide transhydrogenase (NNT) deletion mu
Externí odkaz:
https://doaj.org/article/ff5d65fed52c4d5e9b430969e7092d39
Autor:
Regan Roat, Romano Regazzi, Zhiguang Guo, M. M. Hossain, Claudiane Guay, Jenica Christopherson, Colette Free
Publikováno v:
Xenotransplantation. 26(2)
Aberrant microRNA (miRNA) expression levels are associated with various graft rejections. We used our humanized mouse model with transplanted human islets to identify miRNAs in islet grafts related to xenograft rejection and circulating miRNAs associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::536e7b5256c8eccdcd6c3460ee917471
https://pubmed.ncbi.nlm.nih.gov/30461074
https://pubmed.ncbi.nlm.nih.gov/30461074
Publikováno v:
Protocol Exchange.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e9e56926bf2f400c56e4455c515a914
https://doi.org/10.1038/protex.2018.045
https://doi.org/10.1038/protex.2018.045
Autor:
M. M. Hossain, Regan Roat, Zhiguang Guo, Claudiane Guay, Jenica Christopherson, Romano Regazzi, S. Jain, Colette Free
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 17(4)
Currently there is no effective approach for monitoring early β-cell loss during islet graft rejection following human islet transplantation (HIT). Due to ethical and technical constraints, it is difficult to directly study biomarkers of islet destr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::965fcc1193102e29356829a56bbb5373
https://pubmed.ncbi.nlm.nih.gov/27700000
https://pubmed.ncbi.nlm.nih.gov/27700000