Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Regan L. Scott"'
Autor:
Jackson Nteeba, Kaela M Varberg, Regan L Scott, Mikaela E Simon, Khursheed Iqbal, Michael J Soares
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 8, Iss 1 (2020)
Introduction The hemochorial placenta provides a critical barrier at the maternal–fetal interface to modulate maternal immune tolerance and enable gas and nutrient exchange between mother and conceptus. Pregnancy outcomes are adversely affected by
Externí odkaz:
https://doaj.org/article/8157ce38174f4bfd9fba66b62d9fd6b2
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(41)
The hemochorial placentation site is characterized by a dynamic interplay between trophoblast cells and maternal cells. These cells cooperate to establish an interface required for nutrient delivery to promote fetal growth. In the human, trophoblast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f712791d505dbdd4b43b00209c414a6a
https://pubmed.ncbi.nlm.nih.gov/36191208
https://pubmed.ncbi.nlm.nih.gov/36191208
The invasive trophoblast cell lineage in rat and human share crucial responsibilities in establishing the uterine-placental interface of the hemochorial placenta. These observations have led to the rat becoming an especially useful animal model to st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7e3303406fd67fd7f9019d1155cefe7
https://doi.org/10.1101/2023.03.30.534962
https://doi.org/10.1101/2023.03.30.534962
Autor:
Keisuke Kozai, Ayelen Moreno-Irusta, Khursheed Iqbal, Mae-Lan Winchester, Regan L. Scott, Mikaela E. Simon, Masanaga Muto, Marc R. Parrish, Michael J. Soares
Publikováno v:
Development. 150
Hemochorial placentation involves the differentiation of invasive trophoblast cells, specialized cells that possess the capacity to exit the placenta and invade into the uterus where they restructure the vasculature. Invasive trophoblast cells arise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96c811c4236e4b1aa98ebb7a7b1bb65d
https://doi.org/10.1242/dev.201095
https://doi.org/10.1242/dev.201095
Autor:
Keisuke Kozai, Ayelen Moreno-Irusta, Khursheed Iqbal, Mae-Lan Winchester, Regan L. Scott, Mikaela E. Simon, Masanaga Muto, Marc R. Parrish, Michael J. Soares
Hemochorial placentation involves the differentiation of specialized cells called invasive trophoblast cells possessing the capacity to exit the placenta and invade into the uterus where they restructure the vasculature. Invasive trophoblast cells ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee823a61a63fbf1f4e2b1db8d849b4da
https://doi.org/10.1101/2022.06.15.496110
https://doi.org/10.1101/2022.06.15.496110
The hemochorial placentation site is characterized by a dynamic interplay between trophoblast cells and maternal cells. These cells cooperate to establish an interface required for nutrient delivery to promote fetal growth. In the human, trophoblast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c65ea8f966c46c85f68d913fee78c331
https://doi.org/10.1101/2022.06.14.496152
https://doi.org/10.1101/2022.06.14.496152
Autor:
Katherine N. Gibson-Corley, Nazmin Eti, Regan L. Scott, Violet E Klenov, Michael J. Soares, Khursheed Iqbal, Gabriele Ludewig, Susanne Flor, Larry W. Robertson
Publikováno v:
Toxicology
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor involved in the regulation of biological responses to more planar aromatic hydrocarbons, like TCDD. We previously described the sequence of events following exposure of ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe38a24137ed615df65f511e04398dc1
https://europepmc.org/articles/PMC8748418/
https://europepmc.org/articles/PMC8748418/
Autor:
Stephen H. Pierce, Pramod Dhakal, Carrie A. Vyhlidal, Katherine F. Roby, Khursheed Iqbal, Michael J. Soares, Regan L. Scott, Keisuke Kozai
Publikováno v:
Environmental Health Perspectives
Background Our environment is replete with chemicals that can affect embryonic and extraembryonic development. Dioxins, such as 2,3,7,8-tetrachlorodibenzo- p -dioxin (TCDD), are compounds affecting development through the aryl hydrocarbon receptor (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e013c25af77ef419bdaa732c3ae7e05
http://europepmc.org/articles/PMC8574979
http://europepmc.org/articles/PMC8574979
Autor:
Masanaga Muto, Damayanti Chakraborty, Kaela M. Varberg, Ayelen Moreno-Irusta, Khursheed Iqbal, Regan L. Scott, Ross P. McNally, Ruhul H. Choudhury, John D. Aplin, Hiroaki Okae, Takahiro Arima, Shoma Matsumoto, Masatsugu Ema, Alan E. Mast, Elin Grundberg, Michael J. Soares
Publikováno v:
Proc Natl Acad Sci U S A
Hemochorial placentation is characterized by the development of trophoblast cells specialized to interact with the uterine vascular bed. We utilized trophoblast stem (TS) cell and mutant rat models to investigate regulatory mechanisms controlling tro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e518bb825f746938bcad7edf1ac7b0
https://pubmed.ncbi.nlm.nih.gov/34876522
https://pubmed.ncbi.nlm.nih.gov/34876522
Autor:
Jay L. Vivian, Kaela M. Varberg, John D. Aplin, Ruhul Choudhury, Masanaga Muto, Michael J. Soares, Mikaela E Simon, Elin Grundberg, Margaret Gibson, Keisuke Kozai, Takahiro Arima, Khursheed Iqbal, Hiroaki Okae, Regan L. Scott, Rebecca Biswell
Publikováno v:
Proc Natl Acad Sci U S A
Invasive trophoblast cells are critical to spiral artery remodeling in hemochorial placentation. Insufficient trophoblast cell invasion and vascular remodeling can lead to pregnancy disorders including preeclampsia, preterm birth, and intrauterine gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ed4bde041549017c882d1cd24eff3d2
https://doi.org/10.1073/pnas.2016517118
https://doi.org/10.1073/pnas.2016517118