Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Regan J, Anderson"'
Autor:
Anna H. Mooney, Sarah L. Draper, Olivia K. Burn, Regan J. Anderson, Benjamin J. Compton, Chingwen Tang, Kathryn J. Farrand, Pietro Di Lucia, Micol Ravà, Valeria Fumagalli, Leonardo Giustini, Elisa Bono, Dale I. Godfrey, William R. Heath, Weiming Yuan, Francis V. Chisari, Luca G. Guidotti, Matteo Iannacone, John Sidney, Alessandro Sette, Shivali A. Gulab, Gavin F. Painter, Ian F. Hermans
Publikováno v:
JHEP Reports, Vol 6, Iss 5, Pp 101038- (2024)
Background & Aims: Liver diseases resulting from chronic HBV infection are a significant cause of morbidity and mortality. Vaccines that elicit T-cell responses capable of controlling the virus represent a treatment strategy with potential for long-t
Externí odkaz:
https://doaj.org/article/ee2629abc47b4a819f89b5234ea4bfff
Autor:
Kef K Prasit, Laura Ferrer-Font, Olivia K Burn, Regan J Anderson, Benjamin J Compton, Alfonso J Schmidt, Johannes U Mayer, Chun-Jen J Chen, Nathaniel Dasyam, David S Ritchie, Dale I Godfrey, Stephen R Mattarollo, P Rod Dunbar, Gavin F Painter, Ian F Hermans
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Intratumoural administration of unmethylated cytosine-phosphate-guanine motifs (CpG) to stimulate toll-like receptor (TLR)-9 has been shown to induce tumour regression in preclinical studies and some efficacy in the clinic. Because activated natural
Externí odkaz:
https://doaj.org/article/423fa268183140eca4c64e8a2ff85aed
Autor:
Yanyan Li, Katherine Woods, Amber Parry-Strong, Regan J. Anderson, Celina Capistrano, Aurelie Gestin, Gavin F. Painter, Ian F. Hermans, Jeremy Krebs, Olivier Gasser
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The immune system plays a significant role in controlling systemic metabolism. Innate-like T (ILT) cells in particular, such as mucosal-associated invariant T (MAIT) cells, invariant natural killer T (iNKT) cells and γδ T cell receptor expressing c
Externí odkaz:
https://doaj.org/article/f7bea488c2e14977bbb50c30193e257e
Autor:
Taylor R. Cooney, Kathryn Farrand, Sarah L. Draper, Regan J. Anderson, Phillip M. Rendle, Ian F. Hermans, Benjamin J. Compton, Gavin F. Painter
Publikováno v:
Bioconjugate Chemistry.
Autor:
Karmella Naidoo, Aurélie Gestin, Yanyan Li, Ian F. Hermans, Katie Gell, Gavin F. Painter, Andrew J. Marshall, Elizabeth A. Jacobsen, David O’Sullivan, Alfonso J Schmidt, Olivier Gasser, Alissa Cait, Christophe Pellefigues, Katherine Woods, Regan J. Anderson, Johannes U Mayer, Kef K Prasit
Background: Mucosal-associated invariant T (MAIT) cells are unconventional T cells which recognize microbial metabolites presented by the major histocompatibility complex class I-related molecule MR1. Although MAIT cells have been shown to reside in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b876d355c85ce84c5a8acc008659bfba
https://doi.org/10.1111/all.14994
https://doi.org/10.1111/all.14994
Autor:
Michael A. Meijlink, Yu Cheng Chua, Susanna T. S. Chan, Regan J. Anderson, Matthew W. Rosenberg, Anton Cozijnsen, Vanessa Mollard, Geoffrey I. McFadden, Sarah L. Draper, Lauren E. Holz, Ian F. Hermans, William R. Heath, Gavin F. Painter, Benjamin J. Compton
Publikováno v:
RSC Chemical Biology. 3:551-560
Self-adjuvanting vaccines consisting of peptide epitopes conjugated to immune adjuvants are a powerful way of generating antigen-specific immune responses. We previously showed that a Plasmodium-derived peptide conjugated to a rearranged form of α-g
Autor:
Hui Jing Lim, Jacinta M. Wubben, Cristian Pinero Garcia, Sebastian Cruz-Gomez, Jieru Deng, Jeffrey Y.W. Mak, Abderrahman Hachani, Regan J. Anderson, Gavin F. Painter, Jesse Goyette, Shanika L. Amarasinghe, Matthew E. Ritchie, Antoine Roquilly, David P. Fairlie, Katharina Gaus, Jamie Rossjohn, Jose A. Villadangos, Hamish E.G. McWilliam
Publikováno v:
Journal of Cell Biology
Journal of Cell Biology, 2022, 221 (12), pp.e202110125. ⟨10.1083/jcb.202110125⟩
Journal of Cell Biology, 2022, 221 (12), pp.e202110125. ⟨10.1083/jcb.202110125⟩
International audience; MR1 is a highly conserved microbial immune-detection system in mammals. It captures vitamin B–related metabolite antigens from diverse microbes and presents them at the cell surface to stimulate MR1-restricted lymphocytes in
Autor:
Jeffry S Tang, Yanyan Li, Hannah van der Woude, Gavin F. Painter, Andrew J. Marshall, Ian F. Hermans, Olivier Gasser, Regan J. Anderson, Benjamin J. Compton
Publikováno v:
Food & Function. 11:5782-5787
Methylglyoxal (MGO) is the main antimicrobial determinant associated with using Mānuka Honey as a topical dressing. While direct mechanisms of Mānuka honey MGO's antimicrobial activity have been demonstrated, such as disruption of bacterial fimbria
Autor:
Patrick Bertolino, Anton Cozijnsen, Stephen J. Turner, Mireille H. Lahoud, Daniel Fernandez-Ruiz, Benjamin J. Compton, Matthias H. Enders, Lauren E. Holz, Geoffrey I. McFadden, Kathryn J. Farrand, Kirsteen M. Tullett, Ana Maria Valencia-Hernandez, Juby Mathew, Ian F. Hermans, Taryn L. Osmond, Dale I. Godfrey, William R. Heath, David G. Bowen, Vanessa Mollard, Rose May, Thiago M. Steiner, Zhongfang Wang, Gavin F. Painter, Joshua Lange, Lynette Beattie, Catarina F. Almeida, Lukasz Kedzierski, Sarah L. Draper, Jasmine Li, Susanna T. S. Chan, Maria N. de Menezes, Yu Cheng Chua, Katherine Kedzierska, Irina Caminschi, Sonia Ghilas, Regan J. Anderson, Rebecca Seneviratna
Publikováno v:
Science Immunology. 5
Liver resident-memory CD8+ T cells (TRM cells) can kill liver-stage Plasmodium-infected cells and prevent malaria, but simple vaccines for generating this important immune population are lacking. Here, we report the development of a fully synthetic s
Autor:
Benjamin J. Compton, Carole Grasso, Ian F. Hermans, Michael V. Berridge, Ching-Wen Tang, Regan J. Anderson, Cameron S. Field, Gavin F. Painter, Robert Weinkove, Peter M. Ferguson
Publikováno v:
Immunotherapy. 12(6)
Aim: The efficacy of anti-lymphoma vaccines that exploit the cellular adjuvant properties of activated natural killer T (NKT) cells were examined in mouse models of CNS lymphoma. Materials & methods: Vaccines were prepared by either loading the NKT c