A new tool for technical standardization of the Ki67 immunohistochemical assay

Autor: Regan Fulton, Saba Shafi, Jonathan Warrell, Yalai Bai, Mark Gerstein, Ioannis A. Vathiotis, David L. Rimm, Patricia Gaule, Thazin Nwe Aung, Balazs Acs, Myrto Moutafi, Sandra Martinez-Morilla, Benjamin Freiberg

Publikováno v: Mod Pathol

Ki67, a nuclear proliferation-related protein, is heavily used in anatomic pathology but has not become a companion diagnostic or a standard-of-care biomarker due to analytic variability in both assay protocols and interpretation. The International K

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f20ba74272dbae84da3be60599a9f4e
https://doi.org/10.1038/s41379-021-00745-6

Concordance study of PD-L1 expression in primary and metastatic bladder carcinomas: comparison of four commonly used antibodies and RNA expression

Autor: Thomas J. Long, Tatjana Antic, Masha Kocherginsky, Maria S. Tretiakova, Regan Fulton, Allen M. Gown, Cigdem Ussakli

Publikováno v: Modern Pathology. 31:623-632

Therapy with anti-PD-L1 immune check-point inhibitors is approved for several cancers, including advanced urothelial carcinomas. PD-L1 prevalence estimates vary widely in bladder cancer, and lack of correlation between expression and clinical outcome

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a82638749a1d574cd159a3085b57231c
https://doi.org/10.1038/modpathol.2017.188

Novel antibody probes for the characterization of endosialin/TEM-1

Autor: Pankaj Oberoi, Danielle Fernando, Andrew Z. Milinichik, Elizabeth B. Somers, Earl Albone, Brian E. Tomkowicz, Xin Cheng, Young Chul Park, Daniel J. O'Shannessy, Regan Fulton, Michael F. Smith, Stephen M. Jackson, Nicholas C. Nicolaides, Brad Kline

Publikováno v: Oncotarget

// Daniel J. O’Shannessy 1 , Michael F. Smith 1 , Elizabeth B. Somers 1 , Stephen M. Jackson 1 , Earl Albone 1 , Brian Tomkowicz 1 , Xin Cheng 1 , Young Park 1 , Danielle Fernando 1 , Andrew Milinichik 1 , Brad Kline 1 , Regan Fulton 2 , Pankaj Obe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a8743894a63cde69a8dbe21e09f819f
http://europepmc.org/articles/PMC5342488

Evolution of Quality Assurance for Clinical Immunohistochemistry in the Era of Precision Medicine: Part 4: Tissue Tools for Quality Assurance in Immunohistochemistry

Autor: Mogens Vyberg, Molecular Morphology, Carol C. Cheung, Keith W. Miller, Manfred Dietel, Glenn Francis, Paul E. Swanson, Corrado D'Arrigo, Xiaoge Zhou, Merdol Ibrahim, Antonio Marchetti, Clive R. Taylor, Emina Torlakovic, C. Blake Gilks, J. Han van Krieken, Regan Fulton, Jason L. Hornick, Jacqueline A Hall, Søren Nielsen

Publikováno v: Cheung, C C, D'Arrigo, C, Dietel, M, Francis, G D, Fulton, R, Gilks, C B, Hall, J A, Hornick, J L, Ibrahim, M, Marchetti, A, Miller, K, van Krieken, J H, Nielsen, S, Swanson, P E, Taylor, C R, Vyberg, M, Zhou, X, Torlakovic, E E & From the International Society for Immunohistochemistry and Molecular Morphology (ISIMM) and International Quality Network for Pathology (IQN Path) 2017, ' Evolution of Quality Assurance for Clinical Immunohistochemistry in the Era of Precision Medicine : Part 4: Tissue Tools for Quality Assurance in Immunohistochemistry ', Applied Immunohistochemistry & Molecular Morphology, vol. 25, no. 4, pp. 227-230 . https://doi.org/10.1097/PAI.0000000000000469

The numbers of diagnostic, prognostic, and predictive immunohistochemistry (IHC) tests are increasing; the implementation and validation of new IHC tests, revalidation of existing tests, as well as the on-going need for daily quality assurance monito

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f54da385332086180ebabc69e93e873
https://pubmed.ncbi.nlm.nih.gov/27941560

Cutaneous Peripheral T-Cell Lymphoma Associated With a Proliferation of B Cells

Autor: Roger A. Warnke, Regan Fulton, Youn H. Kim, Uma Sundram, Richard T. Hoppe, Ingerlisa W. Mattoch

Publikováno v: American Journal of Clinical Pathology. 131:810-819

Although the new World Health Organization-European Organization for Research and Treatment of Cancer classification focuses on providing uniformity in the diagnosis of cutaneous lymphomas, cutaneous peripheral T-cell lymphoma (PTL) remains a poorly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b55f9c6c6799148681e1dcd5133ca326
https://doi.org/10.1309/ajcp5w0vocsvobra