Zobrazeno 1 - 10
of 219
pro vyhledávání: '"Refractory anemia with ringed sideroblasts"'
Autor:
I. N. Subortseva, A. I. Melikyan
Publikováno v:
Онкогематология, Vol 11, Iss 4, Pp 8-17 (2017)
Chronic myeloid malignancies that have characteristics of both the myelodysplastic and myeloproliferative disorders allocated to myelodysplastic/myeloproliferative diseases (MDS/MPD) group in 2008 World Health Organization classification. This group
Externí odkaz:
https://doaj.org/article/3f8b43ddfe7041ecbe9ba365d3baf45b
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 21:S73-S76
Introduction Myelodysplastic syndromes (MDS) are genomically complex clonal hematopoietic stem cell neoplasms leading to myelodysplasia and ineffective hematopoiesis.1,2 MDS is a disease of older age, clinically manifesting as symptomatic cytopenias
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de65d46765b73740191fe90b32cc8a52
https://doi.org/10.1016/s2152-2650(21)01216-7
https://doi.org/10.1016/s2152-2650(21)01216-7
Autor:
Shuhei Kawata, Fumiaki Urase, Hitoshi Hanamoto, Mitsuhiro Matsuda, Hirohiko Shibayama, Jun Ishikawa, Itaru Matsumura, Kazuo Tsubaki, Yasuyoshi Morita, Terufumi Yamaguchi, Yasuhiro Maeda
Publikováno v:
Cancer Science
Although azacitidine is the first-line drug for higher-risk myelodysplastic syndrome (MDS) patients, its efficacy for lower-risk MDS remains unestablished. Therefore, we conducted a prospective study to examine the efficacy and safety of a 5-day regi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e64a84dda0bacfdd1f24864398d08cc9
https://doi.org/10.1111/cas.13739
https://doi.org/10.1111/cas.13739
Autor:
Jana Štikarová, Jiří Suttnar, Roman Kotlín, Pavel Májek, Kristýna Pimková, Leona Chrastinova, Jan E. Dyr, Alžběta Hlaváčková, Jaroslav Cermak
Publikováno v:
Free Radical Biology and Medicine. 108:1-7
Myelodysplastic syndromes (MDS) represent a heterogeneous group of pre-leukemic disorders, characterized by ineffective hematopoiesis and the abnormal blood cell development of one or more lineages. Oxidative stress, as an important factor in the car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::315819fdf911fa9ecb8a3fe3fec8b61c
https://doi.org/10.1016/j.freeradbiomed.2017.03.007
https://doi.org/10.1016/j.freeradbiomed.2017.03.007
Autor:
Abdulraheem Yacoub, Hugh Y. Rienhoff
Publikováno v:
Blood. 136:23-24
Lysine-specific demethylase-1 (LSD1) is a histone H3 K4 demethylase that plays a critical role in hematopoietic progenitor cell differentiation, in particular, the production of megakaryocytes and erythrocytes from their common classical bi-potent pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45c77a3ab1dc714a9d60de5a25520a85
https://doi.org/10.1182/blood-2020-141989
https://doi.org/10.1182/blood-2020-141989
Autor:
Rosannah C. Cameron, Ellen Fraint, Sara Nik, Teresa V. Bowman, Varun Gupta, Adriana De La Garza
The spliceosomal component Splicing Factor 3B, subunit 1 (SF3B1) is one of the most prevalently mutated factors in the bone marrow failure disorder myelodysplastic syndrome. There is a strong clinical correlation between SF3B1 mutations and erythroid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94000e3268bc967248bd1ae6f07dde42
https://europepmc.org/articles/PMC6650725/
https://europepmc.org/articles/PMC6650725/
Autor:
Laura Porretti, Wilma Barcellini, Giulia Soverini, Alessandra Cattaneo, Francesca Binda, Francesca Guia Imperiali, Agostino Cortelezzi, Anna Zaninoni
Publikováno v:
Transfusion. 56:2037-2041
BACKGROUND Low-risk myelodysplastic syndromes (MDS) show several immunologic abnormalities, including increased frequency of autoimmune manifestations and/or overt autoimmune diseases, whose prognostic significance still remains controversial. STUDY
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55a8044df9ac6b73de9d871895102425
https://doi.org/10.1111/trf.13652
https://doi.org/10.1111/trf.13652
Publikováno v:
DNA and Cell Biology. 34:588-595
Immune dysregulation has been implicated in myelodysplastic syndrome (MDS) pathogenesis. Refractory anemia with ringed sideroblasts (RARS) is a low-risk subtype of MDS. Our previous study has reported an abnormal γδ T cell receptor (TCR) repertoire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a20dd00e51c5f6f9ea2e2eead5eca9
https://doi.org/10.1089/dna.2015.2925
https://doi.org/10.1089/dna.2015.2925
Publikováno v:
Oncology Letters
The current study presents the case of a 63-year-old patient exhibiting refractory anemia with ringed sideroblasts associated with marked thrombocytosis (RARS-T), who was positive for the MPL W515L mutation, but negative for the JAK2 V617F mutation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32285f2058eae91e3b9c5a5649baa876
https://doi.org/10.3892/ol.2014.2754
https://doi.org/10.3892/ol.2014.2754
Autor:
Qi Zhong, Rui Chen, Zhi Liu, Mengdong Yao, Jing Huang, Qing Zhang, Shanyao Zhou, Liling Zheng, Huijuan Shen, Yanling She, Cheng Li, Ruiming Ou, Yangmin Zhu, Shuang Liu
Publikováno v:
Leukemia research. 62
The myelodysplastic syndrome (MDS) represents a heterogeneous group of clonal hematologic stem cell disorders with the characteristic of ineffective hematopoiesis leading to low blood counts, and a risk of progression to acute myeloid leukemia (AML).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b231ef9ce15b9cbadd6e93ed1ba5cd6
https://pubmed.ncbi.nlm.nih.gov/28982058
https://pubmed.ncbi.nlm.nih.gov/28982058