Zobrazeno 1 - 10
of 225
pro vyhledávání: '"Refractory anemia with ring sideroblasts"'
Autor:
Darci Zblewski, Mark R. Litzow, Ayalew Tefferi, Mrinal S. Patnaik, Aref Al-Kali, Beth R. Larrabee, Kebede H. Begna, Naseema Gangat, William J. Hogan, Ronald S. Go, James M. Foran, Michelle A. Elliott
Publikováno v:
Mayo Clinic Proceedings. 94:1467-1474
To study the changes in overall outcome of patients with myelodysplastic syndromes (MDSs) after approval of several treatments.We identified 54,953 MDS cases in the National Cancer Data Base diagnosed from January 1, 2004, through December 31, 2013,
Autor:
Xiaoyi Wang, Jan Philipp Bewersdorf, Nikolai A. Podoltsev, Chi Zhang, Xiaomei Ma, Amer M. Zeidan, Rong Wang, Scott F. Huntington, Steven D. Gore
Publikováno v:
Leukemialymphoma. 62(10)
Existing studies regarding the role of DNA methyltransferase inhibitors (DNMTi) and lenalidomide in refractory anemia with ring sideroblasts (RARS) are limited. Using the surveillance, epidemiology, and end results-medicare database, we assembled a p
Autor:
Markus Rechsteiner, Rudolf Benz, Markus G. Manz, Corinne C Widmer, Kathrin Zimmermann, Stefan Balabanov
Publikováno v:
Leukemialymphoma. 61(10)
The provisional diagnosis refractory anemia with ring sideroblasts and thrombocytosis was recognized in the WHO 2016 revision of the hematologic neoplasm as a distinct entity and was renamed myelod...
Publikováno v:
Clin Lymphoma Myeloma Leuk
Myelodysplastic/myeloproliferative neoplasms (MDS/MPN) are hybrid group of chronic myeloid neoplasms combining features of both MDS and MPN. The World Health Organization classification coined this group designation in 2008 to include chronic myelomo
Publikováno v:
Leukemia research. 94
Background Anabolic steroids, such as danazol, have been used for years in the treatment of myelodysplastic syndromes (MDS). Their successful use has been documented in aplastic anemia, hypoplastic MDS, and immune thrombocytopenia, among other hemato
Autor:
Yosuke Ogata, Hiroko Iizuka, Yuka Harada, Norio Komatsu, Noriko Doki, Masao Hagihara, Kazuteru Ohashi, Naoki Shingai, Hironori Harada
Publikováno v:
International Journal of Hematology. 108:598-606
Splicing factor gene mutations are found in 60-70% of patients with myelodysplastic syndromes (MDS). We investigated the effects of splicing factor gene mutations on the diagnosis, patient characteristics, and prognosis of MDS. A total of 106 patient
Autor:
Marcin W. Wlodarski, Christian P. Kratz, Charlotte M. Niemeyer, Kathrin Thomay, Brigitte Schlegelberger, Mwe Mwe Chao, Victor B Pastor, Detlev Schindler, Gudrun Goehring
Publikováno v:
Klinische Pädiatrie. 229:329-334
Individuals with Fanconi anemia (FA) have a high risk of developing myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML), yet the secondary somatic mutations lending to these malignancies remain to be further elucidated. We employed a next
Publikováno v:
Tropical Journal of Pathology and Microbiology. 3:67-70
Refractory anemia with ring sideroblasts and thrombocytosis (RARS - T) is a rare disease with a controversial status which presents a diagnostic dilemma as it shows overlapping clinical, laboratory and morphological features of two distinct entities-
Autor:
Irene Luna, Mariam Ibáñez, Mar Tormo, José Cervera, Blanca Navarro, Ivan Martin, Laia Pedrola, Esperanza Such, Eva Villamón, Silvestre Oltra, Ana Vicente, Guillermo Sanz, Inés Gómez-Seguí, Miguel A. Sanz, María López-Pavía
Publikováno v:
Leukemia & Lymphoma. 58:1686-1693
The incidence of SF3B1 mutations in patients with RARS is high. Recently, it has been shown that SF3B1 and DNMT3A mutations overlap more often than expected, although it is not clear how this could affect the disease. We studied SF3B1 and DNMT3A in 1
Autor:
Chetasi Talati, Eric Padron
Publikováno v:
Current Hematologic Malignancy Reports. 11:425-433
According to the recently published 2016 World Health Organization (WHO) classification of myeloid malignancies, myelodysplastic/myeloproliferative neoplasms (MDS/MPN) include atypical chronic myeloid leukemia (aCML), MDS/MPN-unclassifiable (MDS/MPN-