Activity-based sensing fluorescent probes for iron in biological systems

Autor: Aron, Allegra T, Reeves, Audrey G, Chang, Christopher J

Publikováno v: In Current Opinion in Chemical Biology April 2018 43:113-118

Oxidative cyclization reagents reveal tryptophan cation–π interactions.

Autor: Xie, Xiao, Moon, Patrick J., Crossley, Steven W. M., Bischoff, Amanda J., He, Dan, Li, Gen, Dao, Nam, Gonzalez-Valero, Angel, Reeves, Audrey G., McKenna, Jeffrey M., Elledge, Susanna K., Wells, James A., Toste, F. Dean, Chang, Christopher J.

Publikováno v: Nature; Mar2024, Vol. 627 Issue 8004, p680-687, 8p

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

A chemiluminescent probe for cellular peroxynitrite using a self-immolative oxidative decarbonylation reaction† †Electronic supplementary information (ESI) available: Additional experimental details, supplementary figures, and scanned spectra. See DOI: 10.1039/c7sc05087a

Autor: Cao, Jian, An, Weiwei, Reeves, Audrey G., Lippert, Alexander R.

Publikováno v: Chemical Science

Peroxynitrite is a damaging agent of oxidative stress that has been difficult to monitor in living cells. Here, an isatin-based chemiluminescent probe for peroxynitrite is reported.
Peroxynitrite (ONOO–) is a highly reactive oxygen species whi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9be8f37beea1af1879cbd70eadf834be
http://europepmc.org/articles/PMC5914148

An Activity-Based Oxaziridine Platform for Identifying and Developing Covalent Ligands for Functional Allosteric Methionine Sites: Redox-Dependent Inhibition of Cyclin-Dependent Kinase 4.

Autor: Gonzalez-Valero A; Department of Chemistry, University of California, Berkeley, California 94720, United States., Reeves AG; Department of Chemistry, University of California, Berkeley, California 94720, United States., Page ACS; Department of Chemistry, University of California, Berkeley, California 94720, United States., Moon PJ; Department of Chemistry, University of California, Berkeley, California 94720, United States., Miller E; Department of Chemistry, University of California, Berkeley, California 94720, United States., Coulonval K; Faculté de Médecine, Institute of Interdisciplinary Research, Université Libre de Bruxelles, Campus Erasme, Brussels 1070, Belgium., Crossley SWM; Department of Chemistry, University of California, Berkeley, California 94720, United States., Xie X; Department of Chemistry, University of California, Berkeley, California 94720, United States., He D; Department of Chemistry, University of California, Berkeley, California 94720, United States., Musacchio PZ; Department of Chemistry, University of California, Berkeley, California 94720, United States., Christian AH; Department of Chemistry, University of California, Berkeley, California 94720, United States., McKenna JM; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Lewis RA; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Fang E; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Dovala D; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Lu Y; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., McGregor LM; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Schirle M; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Tallarico JA; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States., Roger PP; Faculté de Médecine, Institute of Interdisciplinary Research, Université Libre de Bruxelles, Campus Erasme, Brussels 1070, Belgium., Toste FD; Department of Chemistry, University of California, Berkeley, California 94720, United States., Chang CJ; Department of Chemistry, University of California, Berkeley, California 94720, United States.; Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, United States.

Publikováno v: Journal of the American Chemical Society [J Am Chem Soc] 2022 Dec 21; Vol. 144 (50), pp. 22890-22901. Date of Electronic Publication: 2022 Dec 09.