Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Reetu R. Singh"'
Autor:
Reetu R. Singh, Zoe McArdle, Harshil Singh, Lindsea C. Booth, Clive N. May, Geoffrey A. Head, Karen M. Moritz, Markus P. Schlaich, Kate M. Denton
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Renal sympathetic nerves contribute to renal excretory function during volume expansion. We hypothesized that intact renal innervation is required for excretion of a fluid/electrolyte load in hypertensive chronic kidney disease (CKD) and nor
Externí odkaz:
https://doaj.org/article/b13e539237454fc69489a5ca369b4622
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Children born with a solitary functioning kidney (SFK) have an increased risk of hypertension and kidney disease from early in adulthood. In response to a reduction in kidney mass, the remaining kidney undergoes compensatory kidney growth. This is as
Externí odkaz:
https://doaj.org/article/8f51d01e3c074f7cad7ce3501059a715
Autor:
Emily S. Dorey, Sarah L. Walton, Jacinta I. Kalisch‐Smith, Tamara M. Paravicini, Emelie M. Gardebjer, Kristy A. Weir, Reetu R. Singh, Helle Bielefeldt‐Ohmann, Stephen T. Anderson, Mary E. Wlodek, Karen M. Moritz
Publikováno v:
Physiological Reports, Vol 7, Iss 21, Pp n/a-n/a (2019)
Abstract Maternal alcohol consumption can impair renal development and program kidney dysfunction in offspring. Given that most women who drink alcohol cease consumption upon pregnancy recognition, we aimed to investigate the effect of alcohol around
Externí odkaz:
https://doaj.org/article/298effb342bb44d39fefa50abeadfcca
Autor:
Zoe McArdle, Reetu R. Singh, Helle Bielefeldt-Ohmann, Karen M. Moritz, Kate M. Denton, Michiel F. Schreuder
Publikováno v:
Clinical Science, 137, 603-615
Clinical Science, 137, 8, pp. 603-615
Clinical Science, 137, 8, pp. 603-615
A child with a congenital solitary functioning kidney (SFK) may develop kidney disease from early in life due to hyperfiltration injury. Previously, we showed in a sheep model of SFK that brief angiotensin-converting enzyme inhibition (ACEi) early in
Autor:
Zoe McArdle, Reetu R. Singh, Helle Bielefeldt-Ohmann, Karen M. Moritz, Michiel F. Schreuder, Kate M. Denton
Publikováno v:
Journal of the American Society of Nephrology, 33, 1341-1356
Journal of the American Society of Nephrology, 33, 7, pp. 1341-1356
J Am Soc Nephrol
Journal of the American Society of Nephrology, 33, 7, pp. 1341-1356
J Am Soc Nephrol
Item does not contain fulltext BACKGROUND: Children born with a solitary functioning kidney (SFK) are predisposed to develop hypertension and kidney injury. Glomerular hyperfiltration and hypertrophy contribute to the pathophysiology of kidney injury
Autor:
Markus P. Schlaich, Karen M. Moritz, Lindsea C. Booth, Geoff Head, Kate M. Denton, Clive N. May, Zoe McArdle, Reetu R. Singh
Publikováno v:
Hypertension. 79:261-270
Majority of patients with hypertension and chronic kidney disease (CKD) undergoing renal denervation (RDN) are maintained on antihypertensive medication. However, RDN may impair compensatory responses to hypotension induced by blood loss. Therefore,
Autor:
Roberto B. Pontes, Lindsea C. Booth, Zoe McArdle, Yugeesh R Lankadeva, Markus P. Schlaich, Reetu R. Singh, Song T. Yao, Sally G Hood, Clive N. May
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 317:R319-R327
Catheter-based renal denervation (RDN) was introduced as a treatment for resistant hypertension. There remain critical questions regarding the physiological mechanisms underlying the hypotensive effects of catheter-based RDN. Previous studies indicat
Autor:
Geoff Head, Markus P. Schlaich, Paul Lombardo, Karen M. Moritz, Clive N. May, Lindsea C. Booth, Zoe McArdle, Michael Iudica, Gavin W. Lambert, Helena C. Parkington, Reetu R. Singh, Lawrence K. Easton, Kate M. Denton
Publikováno v:
Hypertension. 73:718-727
We examined whether renal denervation (RDN) reduced blood pressure (BP), improved glomerular filtration rate, albuminuria, and left ventricular mass in sheep with hypertensive chronic kidney disease (CKD). To examine whether renal nerve function retu
Autor:
Lindsea C. Booth, Clive N. May, Kate M. Denton, Zoe McArdle, Geoff Head, Karen M. Moritz, Markus P. Schlaich, Reetu R. Singh
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 77(4)
Overactivity of renal sympathetic nerves and nitric oxide (NO) deficiency occur in hypertensive chronic kidney disease (CKD). In sheep with hypertensive CKD and NO deficiency, renal denervation (RDN) reduces blood pressure and improves kidney functio
Publikováno v:
Kidney International Reports, Vol 6, Iss 4, Pp S169-S170 (2021)