Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Reetta Nätkin"'
Autor:
Reetta Nätkin, Pasi Pennanen, Heimo Syvälä, Merja Bläuer, Juha Kesseli, Teuvo L J Tammela, Matti Nykter, Teemu J Murtola
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281645 (2023)
Androgen deprivation therapy is the cornerstone treatment of advanced prostate cancer. Eventually prostate cancer cells overcome androgen deprivation therapy, giving rise to castration resistant prostate cancer (CRPC) characterized by increased andro
Externí odkaz:
https://doaj.org/article/9203e67f881845b9a88f84cbfa676d4a
Autor:
Anna Aakula, Mukund Sharma, Francesco Tabaro, Reetta Nätkin, Jesse Kamila, Henrik Honkanen, Matthieu Schapira, Cheryl Arrowsmith, Matti Nykter, Jukka Westermarck
RAS-mediated human cell transformation requires inhibition of the tumor suppressor protein phosphatase 2A (PP2A). However, the phosphoprotein targets and cellular processes in which RAS and PP2A activities converge in human cancers have not been syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::971a49012655da7868b77c14ee29502c
https://trepo.tuni.fi/handle/10024/147274
https://trepo.tuni.fi/handle/10024/147274
Autor:
Anna Aakula, Mukund Sharma, Francesco Tabaro, Reetta Nätkin, Jesse Kamila, Henrik Honkanen, Matthieu Schapira, Cheryl Arrowsmith, Matti Nykter, Jukka Westermarck
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e9d1b656bd8b2b764c5d466cf4d53ec
https://doi.org/10.15252/rc.2022436760
https://doi.org/10.15252/rc.2022436760
Autor:
Sallamari Henttinen, Andrew Erickson, Roosa Kaarijärvi, Heidi Kaljunen, Tapio Visakorpi, Merja Bläuer, Alfonso Urbanucci, Mari Lahnalampi, Elisa M. Vuorinen, Paolo Cremaschi, Gerhardt Attard, Stefan Prekovic, Wout Devlies, Teuvo L.J. Tammela, Tomi Häkkinen, Karolina Nowakowska, Alastair D. Lamb, Sinja Taavitsainen, Shaolong Cao, Florian Handle, Antti Kiviaho, Teemu Tolonen, Kirsi Ketola, Heimo Syvälä, Daniel Wetterskog, Wenyi Wang, Kirsi J. Granberg, Ian G. Mills, Nikolai Engedal, Reetta Nätkin, Matti Nykter, Frank Claessens, Teemu J. Murtola
Prostate cancer is heterogeneous and patients would benefit from methods that stratify those who are likely to respond to systemic therapy. We employed single-cell assays for transposase-accessible chromatin (ATAC) and RNA sequencing in models of ear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b12c9acb9aa5d20e72188dbcfe28bfb6
https://doi.org/10.21203/rs.3.rs-384422/v1
https://doi.org/10.21203/rs.3.rs-384422/v1
Autor:
Sinja Taavitsainen, Nikolai Engedal, Shaolong Cao, Florian Handle, Andrew Erickson, Stefan Prekovic, Daniel Wetterskog, Teemu Tolonen, Elisa M. Vuorinen, Antti Kiviaho, Reetta Nätkin, Tomi Häkkinen, Wout Devlies, Sallamari Henttinen, Roosa Kaarijärvi, Mari Lahnalampi, Heidi Kaljunen, Karolina Nowakowska, Heimo Syvälä, Merja Bläuer, Paolo Cremaschi, Frank Claessens, Tapio Visakorpi, Teuvo L. Tammela, Teemu Murtola, Kirsi J. Granberg, Alastair D. Lamb, Kirsi Ketola, Ian G. Mills, Gerhardt Attard, Wenyi Wang, Matti Nykter, Alfonso Urbanucci
Publikováno v:
Cancer Research. 82:401-401
Resistance to androgen receptor-targeted therapy due to tumor heterogeneity and clonal evolution is a key challenge for improving prostate cancer outcomes. Despite this, the transcriptomic and chromatin accessibility changes contributing to the emerg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::072e61950fa9ada0def58bd2e66e6fb9
https://doi.org/10.1158/1538-7445.am2022-401
https://doi.org/10.1158/1538-7445.am2022-401
Autor:
Reetta Nätkin, Niina H. Ikonen, Teuvo L.J. Tammela, Paavo Raittinen, Pasi Pennanen, Teemu T. Murtola, Matti Nykter, Pauliina Ilmonen, Heimo Syvälä, Merja Bläuer
Publikováno v:
Cancer Research. 80:5913-5913
Metastatic prostate cancer is non-curable fatal disease requiring active treatment. Prostate cancer cell proliferation requires androgen hormones mediated by androgen receptor (AR). Typical metastatic prostate cancer treatment exploits this dependenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3b08cd6ee9779fcb6ec6bcfa696a974
https://doi.org/10.1158/1538-7445.am2020-5913
https://doi.org/10.1158/1538-7445.am2020-5913