Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Reesha R Patel"'
Autor:
Kayla Frank, Shawn Abeynaike, Rana Nikzad, Reesha R Patel, Amanda J Roberts, Marisa Roberto, Silke Paust
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0239246 (2020)
Alcohol use disorder (AUD) is a chronic relapsing disorder characterized by an impaired ability to stop or control alcohol use despite adverse social, occupational, or health consequences. AUD is associated with a variety of physiological changes and
Externí odkaz:
https://doaj.org/article/027867307a9943d297ade7d8b899f42f
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133485 (2015)
Voltage-gated sodium channels are responsible for the initiation and propagation of action potentials (APs). Two brain isoforms, Nav1.1 and Nav1.6, have very distinct cellular and subcellular expression. Specifically, Nav1.1 is predominantly expresse
Externí odkaz:
https://doaj.org/article/fac42460566a4987b4b1c40bb8bc95a5
Autor:
Reesha R. Patel, Pauravi Gandhi, Kathryn Spencer, Nihal A. Salem, Chloe. M. Erikson, Vittoria Borgonetti, Roman Vlkolinsky, Larry Rodriguez, Tali Nadav, Michal Bajo, Amanda J. Roberts, R. Dayne Mayfield, Marisa Roberto
Publikováno v:
Neurobiology of Stress, Vol 31, Iss , Pp 100657- (2024)
Chronic ethanol dependence and withdrawal activate corticotropin releasing factor (CRF)-containing GABAergic neurons in the medial prefrontal cortex (mPFC), which tightly regulate glutamatergic pyramidal neurons. Using male CRF1:GFP reporter mice, we
Externí odkaz:
https://doaj.org/article/d2231a05ef614ae7b4944802b1177bc2
Autor:
Florence P. Varodayan, Reesha R. Patel, Alessandra Matzeu, Sarah A. Wolfe, Dallece E. Curley, Sophia Khom, Pauravi J. Gandhi, Larry Rodriguez, Michal Bajo, Shannon D’Ambrosio, Hui Sun, Tony M. Kerr, Rueben A. Gonzales, Lorenzo Leggio, Luis A. Natividad, Carolina L. Haass-Koffler, Rémi Martin-Fardon, Marisa Roberto
Publikováno v:
Biol Psychiatry
BACKGROUND: Alcohol use disorder (AUD) is a leading preventable cause of death. The central amygdala (CeA) is a hub for stress and AUD, while dysfunction of the noradrenaline (NA) stress system is implicated in AUD relapse. METHODS: Here we investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a4550499e0076c55ab4df29a54f31a8
https://doi.org/10.1016/j.biopsych.2022.02.006
https://doi.org/10.1016/j.biopsych.2022.02.006
Autor:
Kathleen A. Grant, Verginia C. Cuzon Carlson, Rebecca Agnore, Suzanne S. Fei, Reesha R. Patel, Marisa Roberto, Vanessa A. Jimenez, Michal Bajo, Lina Gao, Florence P. Varodayan, Nicole A.R. Walter, Melissa A. Herman
Publikováno v:
Neuropsychopharmacology
A major barrier to remission from an alcohol use disorder (AUD) is the continued risk of relapse during abstinence. Assessing the neuroadaptations after chronic alcohol and repeated abstinence is important to identify mechanisms that may contribute t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37516760c7bd687ab11eac21a56579b8
https://doi.org/10.1038/s41386-021-01231-y
https://doi.org/10.1038/s41386-021-01231-y
Autor:
Francisco J. Flores‐Ramirez, Florence P. Varodayan, Reesha R. Patel, Jessica M. Illenberger, Francesca Di Ottavio, Marisa Roberto, Rémi Martin‐Fardon
Publikováno v:
British journal of pharmacology.
A major problem managing alcohol use disorder is the high vulnerability to relapse, even after long periods of abstinence. Chronic alcohol use dysregulates stress responsivity, rendering this system hyporesponsive and making individuals vulnerable to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee719086c93514a145a032d9245f52e2
https://pubmed.ncbi.nlm.nih.gov/36537731
https://pubmed.ncbi.nlm.nih.gov/36537731
Autor:
Roman Vlkolinsky, Reesha R. Patel, Sarah A. Wolfe, Michal Bajo, Larry Rodriguez, Pauravi J Gandhi, Marisa Roberto, Dean Kirson, Florence P. Varodayan, Sophia Khom
Publikováno v:
Alcohol Alcohol
Aims Alcohol use disorder (AUD) is linked to hyperactivity of brain stress systems, leading to withdrawal states which drive relapse. AUD differs among the sexes, as men are more likely to have AUD than women, but women progress from casual use to bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb0329bba12788d3893d4df58bf3750c
https://doi.org/10.1093/alcalc/agab034
https://doi.org/10.1093/alcalc/agab034
Autor:
Larry Rodriguez, Dean Kirson, Sarah A. Wolfe, Reesha R. Patel, Florence P. Varodayan, Angela E. Snyder, Pauravi J. Gandhi, Sophia Khom, Roman Vlkolinsky, Michal Bajo, Marisa Roberto
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 14; Pages: 7842
Alcohol use disorder (AUD) is a chronically relapsing disease characterized by loss of control in seeking and consuming alcohol (ethanol) driven by the recruitment of brain stress systems. However, AUD differs among the sexes: men are more likely to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c503baa82e2eaa92c99a6b62f3a8e86
Autor:
Fergil Mills, Christopher R. Lee, James R. Howe, Hao Li, Shan Shao, Maria N. Keisler, Mackenzie E. Lemieux, Felix H. Taschbach, Laurel R. Keyes, Matilde Borio, Hannah S. Chen, Reesha R. Patel, Alexa L. Gross, Jeremy Delahanty, Christian Cazares, Liezl Maree, Romy Wichmann, Talmo D. Pereira, Marcus K. Benna, Cory M. Root, Kay M. Tye
Publikováno v:
SSRN Electronic Journal.
SUMMARYIn order to respond appropriately to threats in the environment, the brain must rapidly determine whether a stimulus is important and whether it is positive or negative, and then use that information to direct behavioral responses. Neurons in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c8b1b8a25cfacf82c025e87bdd6d171
https://doi.org/10.2139/ssrn.4268609
https://doi.org/10.2139/ssrn.4268609
Autor:
Reesha R. Patel, Sarah A. Wolfe, Vittoria Borgonetti, Pauravi J. Gandhi, Larry Rodriguez, Angela E. Snyder, Shannon D’Ambrosio, Michal Bajo, Alain Domissy, Steven Head, Candice Contet, R. Dayne Mayfield, Amanda J. Roberts, Marisa Roberto
Publikováno v:
Molecular psychiatry. 27(8)
Prefrontal circuits are thought to underlie aberrant emotion contributing to relapse in abstinence; however, the discrete cell-types and mechanisms remain largely unknown. Corticotropin-releasing factor and its cognate type-1 receptor, a prominent br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0495f50faef33b7de65e03b239cc283
https://pubmed.ncbi.nlm.nih.gov/35668157
https://pubmed.ncbi.nlm.nih.gov/35668157