Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Reena Chib"'
Publikováno v:
Research on Chemical Intermediates. 43:7319-7329
In this manuscript we have demonstrated a new approach for the synthesis of 2-amino-4H-chromen-4-ylphosphonates and β-phosphonomalonates linked 2-chloroquinoline-3-carbaldehyde by modified one-pot three-component tandem Knoevenagel–Phospha-Michael
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01c832716378f0cf68e14bfa73880355
https://doi.org/10.1007/s11164-017-3077-2
https://doi.org/10.1007/s11164-017-3077-2
Autor:
Bhahwal Ali Shah, Inshad Ali Khan, Reena Chib, Sundeep Jaglan, Shekaraiah Devari, Ajai Prakash Gupta, Ramesh Deshidi, Rashmi Sharma, Manoj Kushwaha
Publikováno v:
ChemistrySelect. 2:364-368
An endophytic fungus, Alternaria alternata was isolated from Grewia asiatica. Upscaling of the fermentation broth led to the isolation of a new structural isomer of alternariol (3), along with alternariol (1) and alternariol 9-methyl ether (2). Addit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bcf7f15ffbc8875aa09e64438dd6d79
https://doi.org/10.1002/slct.201601649
https://doi.org/10.1002/slct.201601649
Autor:
Inshad Ali Khan, Chitra Rani, Debaraj Mukherjee, Reena Chib, Urmila Jamwal, Asha Chaubey, Mallikharjuna Rao Lambu, Priya Wazir, Rashmi Sharma
Publikováno v:
SLAS Discovery. 21:342-353
Secondary metabolite of Aspergillus terreus, terreic acid, is a reported potent antibacterial that was identified more than 60 years ago, but its cellular target(s) are still unknown. Here we screen its activity against the acetyltransferase domain o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0acc8b48b468b17d6aa090d661244db
https://doi.org/10.1177/1087057115625308
https://doi.org/10.1177/1087057115625308
Autor:
Amit Nargotra, Rukmankesh Mehra, Priya Wazir, Inshad Ali Khan, Chitra Rani, Rashmi Sharma, Reena Chib
Publikováno v:
Tuberculosis. 95:664-677
N-acetylglucosamine-1-phosphate uridyltransferase (GlmU) is a pivotal bifunctional enzyme, its N and C terminal domains catalyzes uridyltransferase and acetyltransferase activities, respectively. Final product of GlmU catalyzed reaction, uridine-diph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a845cd98d72beecb974d9a1ad1d42a3a
https://doi.org/10.1016/j.tube.2015.06.003
https://doi.org/10.1016/j.tube.2015.06.003
Autor:
Inshad Ali Khan, Parduman R. Sharma, Chitra Rani, Rukmankesh Mehra, Vikrant Singh Rajput, Sunil Kumar, Samsher Singh, Amit Nargotra, Rashmi Sharma, Reena Chib
Publikováno v:
Applied Microbiology and Biotechnology. 100:3071-3085
This study aims at identifying novel chemical scaffolds as inhibitors specific to the acetyltransferase domain of a bifunctional enzyme, Escherichia coli GlmU, involved in the cell wall biosynthesis of Gram-negative organisms. A two-pronged approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da8d1a70e237ce96df109ffc731f917d
https://doi.org/10.1007/s00253-015-7123-y
https://doi.org/10.1007/s00253-015-7123-y
Autor:
Samsher Singh, Gurleen Kour, Sunil Kumar, Ram A. Vishwakarma, Parvinder Pal Singh, Reena Chib, Kushalava Reddy Yempalla, Sushil Raina, Shweta Sharma, Gitam Singh, Sonali S. Bharate, Priya Wazir, Inshad Ali Khan, Gurunadham Munagala
Publikováno v:
ACS Medicinal Chemistry Letters. 6:1059-1064
Novel polar functionalities containing 6-nitro-2,3-dihydroimidazooxazole (NHIO) analogues were synthesized to produce a compound with enhanced solubility. Polar functionalities including sulfonyl, uridyl, and thiouridyl-bearing NHIO analogues were sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30fc5efece7b6e9d3a238b75425274b2
https://doi.org/10.1021/acsmedchemlett.5b00202
https://doi.org/10.1021/acsmedchemlett.5b00202
Autor:
Inshad Ali Khan, Kushalava Reddy Yempalla, Gurunadham Munagala, Reena Chib, Rukmankesh Mehra, Amit Nargotra, Farrah Gul Khan, Parvinder Pal Singh
Publikováno v:
Molecular Diversity. 19:1003-1019
Mycobacterium tuberculosis bacteria are cause deadly infections in patients. The rise of multidrug resistance associated with tuberculosis further makes the situation worse in treating the disease. M. tuberculosis proteasome is necessary for the path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35d1ebca5ac588fede3e32463a17a2eb
https://doi.org/10.1007/s11030-015-9624-0
https://doi.org/10.1007/s11030-015-9624-0
Autor:
Ruchi Khajuria, Subrayashastry Aravinda, Rajinder Parshad, Ram A. Vishwakarma, Reena Chib, Santosh Kumar Guru, Inshad Ali Khan, Anup Singh Pathania, Sandip B. Bharate, Vivek K. Gupta, Baljinder Singh, Rashmi Sharma, Shashi Bhushan
Publikováno v:
Tetrahedron Letters. 54:6695-6699
From an antimicrobial gram-positive actinomycete strain of Saccharomonospora azurea (MTCC11714) isolated from high altitude soil of Kargil (J&K, India), a new isocoumarin saccharonol B (2) along with two known compounds viz. saccharonol A (1) and pie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa57eba98a2490a6ac49f3ad03810bc3
https://doi.org/10.1016/j.tetlet.2013.09.060
https://doi.org/10.1016/j.tetlet.2013.09.060
Autor:
Inshad Ali Khan, Reena Chib, Reyaz ur Rasool, Baldev Singh, Deepak Sharma, Anindya Goswami, Altaf Hussain, Rashmi Sharma, Anil K. Tripathi, Debaraj Mukherjee
Publikováno v:
Medicinal Chemistry Research. 23:1643-1653
A series of bisindolylmethanes (BIMs) (1a–7j) including hybrid BIMs 6a–6c were prepared for bioevaluation. The results of initial antimicrobial screening of compounds 1a–6c showed compounds 2b, 2m, 4a and 5b to be the most potent inhibitors, ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4617bcf2abf19f0ee9aa3e7c221ff4f6
https://doi.org/10.1007/s00044-013-0764-4
https://doi.org/10.1007/s00044-013-0764-4
Autor:
Rukmankesh Mehra, Inshad Ali Khan, Amit Kumar, Monika Gupta, Reena Chib, Priya Wazir, Amit Nargotra, Vikrant Singh Rajput
Publikováno v:
Journal of chemical information and modeling. 56(5)
Mycobacterium tuberculosis shikimate kinase (Mtb-SK) is a key enzyme involved in the biosynthesis of aromatic amino acids through the shikimate pathway. Since it is proven to be essential for the survival of the microbe and is absent from mammals, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f8dcb5ab89f7d4de9c662271d637fb4
https://pubmed.ncbi.nlm.nih.gov/27149193
https://pubmed.ncbi.nlm.nih.gov/27149193