Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Reena Chawla"'
Autor:
Rameez Ali, Sreenivasa Anugu, Reena Chawla, Violeta G. Demillo, Florian Goulinet-Mateo, Sagar Gyawali, Sunil Hamal, Dylan E. Jones, Katrin Lamprecht, Truc Le, Liezel A. Lumangtad, Nicholas C. Pflug, Alekhya Sama, Emily D. Scarbrough, Thomas W. Bell
Publikováno v:
ACS Omega, Vol 4, Iss 1, Pp 1254-1264 (2019)
Externí odkaz:
https://doaj.org/article/011f439bb7a647cc920377bf1d077276
Autor:
Marcel Patek, Zhiming Shan, Song Cai, May Khanna, Vijay Gokhale, Todd W. Vanderah, Reena Chawla, Shreya S. Bellampalli, Taylor Joel Woodward, David D. Scott, Angie Dorame, Yuan Zhou, Lindsey A. Chew, Aude Chefdeville, Kimberly Gomez, Cynthia L. Madura, Andrea G. Hohmann, Liberty François-Moutal, Jörg Isensee, Shizhen Luo, Jie Yu, Rajesh Khanna, Samantha Perez-Miller, Tim Hucho, Aubin Moutal
Publikováno v:
Science translational medicine. 13(619)
The voltage-gated sodium NaV1.7 channel, critical for sensing pain, has been actively targeted by drug developers; however, there are currently no effective and safe therapies targeting NaV1.7. Here, we tested whether a different approach, indirect N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0e648398c430d065425e2366a825e6
https://pubmed.ncbi.nlm.nih.gov/34824392
https://pubmed.ncbi.nlm.nih.gov/34824392
Autor:
Melinda Fitzgerald, Amy L. Kretzmann, Haibo Jiang, Jeffrey A. Keelan, Tristan D. Clemons, Alaa M. Munshi, Laurence H. Hurley, Jean-Pierre Veder, Jessica A. Kretzmann, Charles S. Bond, Diwei Ho, Nicole M. Smith, Michael Archer, Priyanka Toshniwal, Michelle Nguyen, Amanda J. Blythe, Cameron W. Evans, Paul Guagliardo, Marck Norret, Reena Chawla, K. Swaminathan Iyer, Martin Saunders, Matt R. Kilburn
Publikováno v:
Nature Nanotechnology. 13:1148-1153
Gold nanorods are one of the most widely explored inorganic materials in nanomedicine for diagnostics, therapeutics and sensing1. It has been shown that gold nanorods are not cytotoxic and localize within cytoplasmic vesicles following endocytosis, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3204b1dac4cd6d1f1cff01b5adf2a93
https://doi.org/10.1038/s41565-018-0272-2
https://doi.org/10.1038/s41565-018-0272-2
Autor:
Prashansa Agrawal, Laurence H. Hurley, Reena Chawla, Natalie A. Van Ert, Christine E. Kaiser, Danzhou Yang
Publikováno v:
Journal of the American Chemical Society. 139:8522-8536
Activating KRAS mutations frequently occur in pancreatic, colorectal, and lung adenocarcinomas. While many attempts have been made to target oncogenic KRAS, no clinically useful therapies currently exist. Most efforts to target KRAS have focused on i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::928d244ab2a33e33414d2f580c5c29e6
https://doi.org/10.1021/jacs.7b02046
https://doi.org/10.1021/jacs.7b02046
Autor:
Eddie T. Chiang, Venkateshwar Reddy Chappeta, Megan A. Turnidge, Reena Chawla, Danzhou Yang, Quinea R. Lassiter, Carmen Lee, Hector Quijada, Robert V. Brown, Shivani Phanse, Ping Zhao, Joe G.N. Garcia, Ting Wang, Laurence H. Hurley, Buket Onel, Sara M. Camp, Guanhui Wu, Vijay Gokhale
Publikováno v:
Journal of the American Chemical Society. 139:7456-7475
The platelet-derived growth factor receptor β (PDGFR-β) signaling pathway is a validated and important target for the treatment of certain malignant and nonmalignant pathologies. We previously identified a G-quadruplex-forming nuclease hypersensiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fefd75fd34ef0c0d1961b72733d2b955
https://doi.org/10.1021/jacs.6b10028
https://doi.org/10.1021/jacs.6b10028
Autor:
Thomas W. Bell, Nicholas C. Pflug, Sreenivasa Anugu, Florian Goulinet-Mateo, Katrin Lamprecht, Reena Chawla, Rameez Ali, Violeta G. Demillo, Emily D. Scarbrough, Sunil Hamal, Alekhya Sama, Sagar Gyawali, Truc D. T. Le, Liezel A. Lumangtad, Dylan E. Jones
Publikováno v:
ACS Omega, 4 (1)
ACS Omega, Vol 4, Iss 1, Pp 1254-1264 (2019)
ACS Omega
ACS Omega, Vol 4, Iss 1, Pp 1254-1264 (2019)
ACS Omega
Macrocyclic triamine disulfonamides can be synthesized by double Tsuji–Trost N-allylation reaction of open-chain disulfonamides with 2-alkylidene-1,3-propanediyl bis(carbonates). The previously used Atkins–Richman macrocyclization method generall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::168293d30a812016f387b7d87a176d1c
https://hdl.handle.net/20.500.11850/322310
https://hdl.handle.net/20.500.11850/322310
Autor:
Reena Chawla, Nicholas C. Pflug, Dominique Schols, Victor Van Puyenbroeck, Thomas W. Bell, Kurt Vermeire, Alekhya Sama, Rameez Ali
Publikováno v:
Journal of Medicinal Chemistry. 59:2633-2647
Cyclotriazadisulfonamide prevents HIV entry into cells by down-modulating surface CD4 receptor expression through binding to the CD4 signal peptide. According to a two-site binding model, 28 new unsymmetrical analogues bearing a benzyl tail group and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f186241ea6c92aceb7e98b2d1cfb36f
https://doi.org/10.1021/acs.jmedchem.5b01832
https://doi.org/10.1021/acs.jmedchem.5b01832
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