Translating Senotherapeutic Interventions into the Clinic with Emerging Proteomic Technologies

Autor: Amit K. Dey, Reema Banarjee, Mozhgan Boroumand, Delaney V. Rutherford, Quinn Strassheim, Thedoe Nyunt, Bradley Olinger, Nathan Basisty

Publikováno v: Biology, Vol 12, Iss 10, p 1301 (2023)

Cellular senescence is a state of irreversible growth arrest with profound phenotypic changes, including the senescence-associated secretory phenotype (SASP). Senescent cell accumulation contributes to aging and many pathologies including chronic inf

Externí odkaz: https://doaj.org/article/36b5472a47b14165ba7c0dbb97d237f1

Plasma-Derived Extracellular Vesicles Reveal Galectin-3 Binding Protein as Potential Biomarker for Early Detection of Glioma

Autor: Rashmi Rana, Kirti Chauhan, Poonam Gautam, Mahesh Kulkarni, Reema Banarjee, Parul Chugh, Satnam Singh Chhabra, Rajesh Acharya, Samir Kumar Kalra, Anshul Gupta, Sunila Jain, Nirmal Kumar Ganguly

Publikováno v: Frontiers in Oncology, Vol 11 (2021)

Gliomas are the most common type of the malignant brain tumor, which arise from glial cells. They make up about 40% of all primary brain tumors and around 70% of all primary malignant brain tumors. They can occur anywhere in the central nervous syste

Externí odkaz: https://doaj.org/article/55e46808eb4343358b44bf1f5ff5dba5

Enzymatic and Non-enzymatic Detoxification of Reactive Carbonyl Compounds Improves the Oxidative Stress Tolerance in Cucumber, Tobacco and Rice Seedlings

Autor: Ambekar Nareshkumar, Reema Banarjee, Amarnatha Reddy Vennapusa, Mahesh J. Kulkarni, Makarla Udayakumar, Vargheese Ashwin, Sindhu Subbarao, Vemanna S. Ramu

Publikováno v: Journal of Plant Growth Regulation. 39:1359-1372

Detoxification of reactive carbonyl compounds (RCC) is crucial to sustain cellular activity to improve plant growth and development. Seedling growth is highly affected by accumulation of RCC under stress. We report non-enzymatic, enzymatic mechanisms

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aaf2e8da29e2d31c18f607c5305d2d8f
https://doi.org/10.1007/s00344-020-10072-w

A bright future for proteomics of health and disease. Introduction to the US HUPO 2021 themed issue – proteomics from single cell to systems biology in health and disease

Autor: Lindsay Pino, Reema Banarjee, Nathan Basisty

Publikováno v: Molecular Omics. 18:894-895

Lindsay Pino, Reema Banarjee and Nathan Basisty introduce the Molecular Omics themed issue on proteomics from single cell to systems biology in health and disease.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfa16d12f62d10895f74c41533b7ff67
https://doi.org/10.1039/d2mo90026b

Advanced Glycation End Products Modulate Amyloidogenic APP Processing and Tau Phosphorylation: A Mechanistic Link between Glycation and the Development of Alzheimer's Disease

Autor: Rashmi K. Godbole, Mahesh J. Kulkarni, Robert J. Williams, Omar Kassaar, Kedar B. Batkulwar, Reema Banarjee

Publikováno v: Batkulwar, K, Godbole, R, Banarjee, R, Kassaar, O, Williams, R J & Kulkarni, M 2018, ' Advanced glycation end products modulate amyloidogenic APP processing and Tau phosphorylation: a mechanistic link between glycation and the development of Alzheimer’s disease ', ACS Chemical Neuroscience, vol. 9, no. 5, pp. 988-1000 . https://doi.org/10.1021/acschemneuro.7b00410

Advanced glycation end products (AGEs) are implicated in the pathology of Alzheimer's disease (AD), as they induce neurodegeneration following interaction with the receptor for AGE (RAGE). This study aimed to establish a mechanistic link between AGE-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f90757f40d155c2c160454c8e89e3718
https://pubmed.ncbi.nlm.nih.gov/29384651