Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Reema B. Davis"'
Autor:
Anne M. Talkington, Reema B. Davis, Nicholas C. Datto, Emma R. Goodwin, Laura A. Miller, Kathleen M. Caron
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Lymphatic vessels serve as a major conduit for the transport of interstitial fluid, immune cells, lipids and drugs. Therefore, increased knowledge about their development and function is relevant to clinical issues ranging from chronic inflammation a
Externí odkaz:
https://doaj.org/article/019aee0ac85d4cee9013a87de5c0cf87
Autor:
Carrie J. Shawber, Nicholas C. Datto, Julie Blatt, Kathleen M. Caron, Kristy S. Pahl, Scott V. Smith, Reema B. Davis
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-3 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Autor:
Matthew Harris, Duncan I. Mackie, Reema B. Davis, Kathleen M. Caron, Graham Ladds, Smriti Singh, Danica Dy, Natalie R Nielsen
Publikováno v:
Proc Natl Acad Sci U S A
Receptor-activity-modifying proteins (RAMPs) are single transmembrane-spanning proteins which serve as molecular chaperones and allosteric modulators of G-protein-coupled receptors (GPCRs) and their signaling pathways. Although RAMPs have been previo
Autor:
Wanshu Ma, Lillian Lim, Mark L. Kahn, Michael J. Soares, Zoltán Jakus, Kathleen M. Caron, John B. Pawlak, Guillermo Oliver, László Bálint, Reema B. Davis, Zoltán Benyó
Publikováno v:
Journal of Clinical Investigation. 129:4912-4921
Molecular heterogeneity of endothelial cells underlies their highly specialized functions during changing physiological conditions within diverse vascular beds. For example, placental spiral arteries (SAs) undergo remarkable remodeling to meet the ev
Autor:
Wenjing Xu, Nathan P. Nelson-Maney, László Bálint, Hyouk-Bum Kwon, Reema B. Davis, Danielle C. M. Dy, James M. Dunleavey, Brad St. Croix, Kathleen M. Caron
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 10; Pages: 5712
Numerous studies have focused on the molecular signaling pathways that govern the development and growth of lymphatics in the hopes of elucidating promising druggable targets. G protein-coupled receptors (GPCRs) are currently the largest family of me
Autor:
Fuad Al Mutairi, Daniel O. Kechele, John Simms, Natalie R Nielsen, Reema B. Davis, Joshua C. Snyder, Harvey J. Kliman, Marc G. Caron, Duncan I. Mackie, David R. Poyner, Jonathan S. Berg, Kathleen M. Caron
Publikováno v:
Journal of Experimental Medicine. 215:2339-2353
We report the first case of nonimmune hydrops fetalis (NIHF) associated with a recessive, in-frame deletion of V205 in the G protein–coupled receptor, Calcitonin Receptor-Like Receptor (hCALCRL). Homozygosity results in fetal demise from hydrops fe
Autor:
Kathleen M. Caron, Shengli Ding, Reema B. Davis, Natalie R Nielsen, Elizabeth S Blakeney, John B. Pawlak
Publikováno v:
ACS pharmacologytranslational science. 2(2)
[Image: see text] The absorption of dietary fat requires complex neuroendocrine-mediated regulation of chylomicron trafficking through enterocytes and intestinal lymphatic vessels. Calcitonin-receptor-like receptor (Calcrl) is a G protein-coupled rec
Autor:
Julie Blatt, Kristy S. Pahl, Nicholas C. Datto, Kathleen M. Caron, Carrie J. Shawber, Reema B. Davis, Scott V. Smith
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Notch expression has been shown to be aberrant in brain arteriovenous malformations (AVM), and targeting Notch has been suggested as an approach to their treatment. It is unclear whether extracranial vascular malformations follow the same patterning
Lymphatics play a critical role in maintaining gastrointestinal homeostasis and in the absorption of dietary lipids, yet their roles in intestinal inflammation remain elusive. Given the increasing prevalence of inflammatory bowel disease, we investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5c92b83e9c1bd8069bab0d52ed9929c
https://europepmc.org/articles/PMC5358488/
https://europepmc.org/articles/PMC5358488/
Publikováno v:
Development. 140:1272-1281
Arteries and veins acquire distinct molecular identities prior to the onset of embryonic blood circulation, and their specification is crucial for vascular development. The transcription factor COUP-TFII currently functions at the top of a signaling