Boosting compromised SARS-CoV-2-specific immunity with mRNA vaccination in liver transplant recipients

Autor: Luxenburger, Hendrik, Reeg, David B., Lang-Meli, Julia, Reinscheid, Matthias, Eisner, Miriam, Bettinger, Dominik, Oberhardt, Valerie, Salimi Alizei, Elahe, Wild, Katharina, Graeser, Anne, Karl, Vivien, Sagar, Emmerich, Florian, Klein, Florian, Panning, Marcus, Huzly, Daniela, Bengsch, Bertram, Boettler, Tobias, Elling, Roland, Thimme, Robert, Hofmann, Maike, Neumann-Haefelin, Christoph

Publikováno v: In Journal of Hepatology May 2023 78(5):1017-1027

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COVID-19 mRNA booster vaccine induces transient CD8+ T effector cell responses while conserving the memory pool for subsequent reactivation.

Autor: Reinscheid, Matthias, Luxenburger, Hendrik, Karl, Vivien, Graeser, Anne, Giese, Sebastian, Ciminski, Kevin, Reeg, David B., Oberhardt, Valerie, Roehlen, Natascha, Lang-Meli, Julia, Heim, Kathrin, Gross, Nina, Baum, Christina, Rieg, Siegbert, Speer, Claudius, Emmerich, Florian, Breisinger, Susanne, Steinmann, Daniel, Bengsch, Bertram, Boettler, Tobias

Publikováno v: Nature Communications; 8/8/2022, Vol. 13 Issue 1, p1-11, 11p

Immunological imprinting shapes the specificity of human antibody responses against SARS-CoV-2 variants.

Autor: Johnston TS; Department of Microbiology, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA.; Institute for Immunology and Immune Health, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA.; Vaccine Research Center, NIAID, NIH; Bethesda, MD.; These authors contributed equally., Li SH; Department of Microbiology, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA.; These authors contributed equally., Painter MM; Institute for Immunology and Immune Health, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA.; These authors contributed equally., Atkinson RK; Department of Microbiology, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA., Douek NR; Institute for Immunology and Immune Health, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA., Reeg DB; Institute for Immunology and Immune Health, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA.; Department of Medicine II (Gastroenterology, Hepatology, Endocrinology and Infectious Diseases), Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany., Douek DC; Vaccine Research Center, NIAID, NIH; Bethesda, MD., Wherry EJ; Institute for Immunology and Immune Health, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA., Hensley SE; Department of Microbiology, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA.; Institute for Immunology and Immune Health, University of Pennsylvania Perelman School of Medicine; Philadelphia, PA.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2024 Jan 09. Date of Electronic Publication: 2024 Jan 09.