Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Reed T. Larson"'
2
Utilizing biocatalysis and a sulfolane-mediated reductive acetal opening to access nemtabrutinib from cyrene
Autor: Nadine Kuhl, Ben W. H. Turnbull, Yining Ji, Reed T. Larson, Michael Shevlin, Christopher K. Prier, Cheol K. Chung, Richard Desmond, Erik Guetschow, Cyndi Qixin He, Tetsuji Itoh, Jeffrey T. Kuethe, Justin A. Newman, Mikhail Reibarkh, Nelo R. Rivera, Gao Shang, Zhixun Wang, Daniel Zewge, David A. Thaisrivongs
Publikováno v: Green Chemistry. 25:606-613
The development of a protecting group-free, 2-step synthesis of 5-amino-2-hydroxymethyltetrahydropyran 1a from biorenewable Cyrene™ is described which renders access to BTK-inhibitor nemtabrutinib (2) more efficient and sustainable.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::76254159f72e72785c230763f61657ab
https://doi.org/10.1039/d2gc04117k
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3
Carboxyboronate as a Versatile In Situ CO Surrogate in Palladium‐Catalyzed Carbonylative Transformations
Autor: Aleksandra Holownia, Andrei K. Yudin, Branden S. Kwak, Reed T. Larson, Chieh-Hung Tien, Alina Trofimova
Publikováno v: Angewandte Chemie. 133:4388-4395
The application of carboxy-MIDA-boronate (MIDA=N-methyliminodiacetic acid) as an in situ CO surrogate for various palladium-catalyzed transformations is described. Carboxy-MIDA-boronate was previously shown to be a bench-stable boron-containing build
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc3550189ae4adeb0112ac8e134fdf36
https://doi.org/10.1002/ange.202010211
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4
Carboxyboronate: A Versatile C1 Building Block
Autor: Diego B. Diaz, Andrei K. Yudin, Reed T. Larson, Chieh-Hung Tien, Aleksandra Holownia
Publikováno v: Angewandte Chemie. 131:15292-15297
The synthesis and applications of carboxy-MIDA-boronate, a novel C1 building block, are described. This molecule is accessible via a ruthenium tetraoxide-mediated cleavage of commercially available ethynyl-MIDA-boronate. In the course of this study,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d54492399415028d197fe979f807a062
https://doi.org/10.1002/ange.201907486
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5
Hydrogen Gas-Mediated Deoxydehydration/Hydrogenation of Sugar Acids: Catalytic Conversion of Glucarates to Adipates
Autor: F. Dean Toste, Stephan J. Zuend, Jianbin Chen, Dominik M. Ohlmann, Martin Alexander Bohn, Woojin Lee, Andrew V. Samant, Reed T. Larson
Publikováno v: Journal of the American Chemical Society, vol 139, iss 40
Larson, RT; Samant, A; Chen, J; Lee, W; Bohn, MA; Ohlmann, DM; et al.(2017). Hydrogen Gas-Mediated Deoxydehydration/Hydrogenation of Sugar Acids: Catalytic Conversion of Glucarates to Adipates. Journal of the American Chemical Society, 139(40), 14001-14004. doi: 10.1021/jacs.7b07801. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/5xx5z43n
© 2017 American Chemical Society. The development of a system for the operationally simple, scalable conversion of polyhydroxylated biomass into industrially relevant feedstock chemicals is described. This system includes a bimetallic Pd/Re catalyst
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb08433715bf43549772914f6ce0c1a7
https://escholarship.org/uc/item/5xx5z43n
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6
ChemInform Abstract: Total Synthesis of the Galbulimima Alkaloids Himandravine and GB17 Using Biomimetic Diels-Alder Reactions of Double Diene Precursors
Autor: Ryan P. Pemberton, Jenna M. Franke, Regan J. Thomson, Reed T. Larson, Dean J. Tantillo
Publikováno v: ChemInform. 47
The enantioselective total syntheses of himandravine and GB17 were completed through a common biomimetic strategy involving Diels–Alder reactions of unusual double diene containing linear precursors. The double diene precursors, containing or lacki
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a15795165b852c36e0f54ec3c25f49f7
https://doi.org/10.1002/chin.201608214
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7
Total Synthesis of the Galbulimima Alkaloid (−)-GB17
Autor: Reed T. Larson, Michael D. Clift, Regan J. Thomson
Publikováno v: Angewandte Chemie International Edition. 51:2481-2484
The first enantioselective total synthesis of (−)-GB17 is reported. Construction of this unique naphthoquinolizinone skeleton was achieved by two stereoselective intramolecular Michael additions. The first of these Michael additions is controlled b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01d654d8a392459780ed97d3bfdb7137
https://doi.org/10.1002/anie.201108227
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8
Total Synthesis of the Galbulimima Alkaloids Himandravine and GB17 Using Biomimetic Diels-Alder Reactions of Double Diene Precursors
Autor: Jenna M. Franke, Reed T. Larson, Dean J. Tantillo, Regan J. Thomson, Ryan P. Pemberton
Publikováno v: Journal of the American Chemical Society. 137(34)
The enantioselective total syntheses of himandravine and GB17 were completed through a common biomimetic strategy involving Diels–Alder reactions of unusual double diene containing linear precursors. The double diene precursors, containing or lacki
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3eda48e5e6d8a1926373db4e7288b8d
https://pubmed.ncbi.nlm.nih.gov/26305231
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