Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Reed Kelso"'
Autor:
Jared Carlson-Stevermer, Reed Kelso, Anastasia Kadina, Sahil Joshi, Nicholas Rossi, John Walker, Rich Stoner, Travis Maures
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
Uncontrolled gene editing can lead to off-target effects and chromosomal translocations. Here the authors develop CRISPRoff, light degradable sgRNAs for titratable and spatially defined gene editing.
Externí odkaz:
https://doaj.org/article/281b8bfd5bf6470ba784a46dec47a11d
Autor:
David, Conant, Tim, Hsiau, Nicholas, Rossi, Jennifer, Oki, Travis, Maures, Kelsey, Waite, Joyce, Yang, Sahil, Joshi, Reed, Kelso, Kevin, Holden, Brittany L, Enzmann, Rich, Stoner
Publikováno v:
The CRISPR Journal. 5:123-130
Efficient and precise genome editing requires a fast, quantitative, and inexpensive assay to assess genotype following editing. Here, we present ICE (Inference of CRISPR Edits), which enables robust analysis of CRISPR edits using Sanger data. ICE pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c33983379b795399534b18584dfdd21
https://doi.org/10.1089/crispr.2021.0113
https://doi.org/10.1089/crispr.2021.0113
Autor:
David T. McSwiggen, Helen Liu, Ruensern Tan, Sebastia Agramunt Puig, Lakshmi B. Akella, Russell Berman, Mason Bretan, Hanzhe Chen, Xavier Darzacq, Kelsey Ford, Ruth Godbey, Eric Gonzalez, Adi Hanuka, Alec Heckert, Jaclyn J. Ho, Stephanie L. Johnson, Reed Kelso, Aaron Klammer, Jifu Li, Kevin Lin, Brian Margolin, Patrick McNamara, Lawrence Meyer, Sarah E. Pierce, Akshay Sule, Yangzhong Tang, Daniel J. Anderson, Hilary P. Beck
The regulation of cell physiology largely depends upon intracellular interactions of functionally distinct proteins that act in combination. These interactions, which are often transient in nature, help to define the motion profiles of proteins. Meas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac3d8c0262997dae5851a5a2a6172235
https://doi.org/10.1101/2023.01.05.522916
https://doi.org/10.1101/2023.01.05.522916
Autor:
Reed Kelso, Jared Carlson-Stevermer, Rich Stoner, Nicholas A. A. Rossi, John R. Walker, Sahil Joshi, Anastasia P. Kadina, Travis J. Maures
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
Nature Communications
Nature Communications
Following introduction of CRISPR-Cas9 components into a cell, genome editing occurs unabated until degradation of its component nucleic acids and proteins by cellular processes. This uncontrolled reaction can lead to unintended consequences including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdb81f96b6f0f8e08088c4ed1ffb2932
http://link.springer.com/article/10.1038/s41467-020-18853-3
http://link.springer.com/article/10.1038/s41467-020-18853-3
Autor:
John M. Leonard, Chris Gee, Hongmei Mo, Mickey S. Urdea, Martin Markowitz, John E. Mittler, Daniel W. Norbeck, P. Scott Eastman, Janice A. Kolberg, Eric Boyer, Reed Kelso
Publikováno v:
Journal of Virology. 72:5154-5164
Ten subjects received 600 to 1,200 mg of the human immunodeficiency virus type 1 (HIV-1) protease inhibitor ritonavir per day. Following 2 weeks of therapy, plasma HIV RNA levels decreased by a mean of 1.57 (range, 0.89 to 1.96) log units. With conti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2dde59c1d3517485cb9c93440030eeb
https://doi.org/10.1128/jvi.72.6.5154-5164.1998
https://doi.org/10.1128/jvi.72.6.5154-5164.1998