Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Reed C Carroll"'
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91288 (2014)
Glaucoma is a progressive neurodegenerative disease of retinal ganglion cells (RGCs) associated with characteristic axon degeneration in the optic nerve. Excitotoxic damage due to increased Ca(2+) influx, possibly through NMDA-type glutamate receptor
Externí odkaz:
https://doaj.org/article/866fe62638bf44b8a5d4d811848daf5b
Publikováno v:
Molecular and Cellular Neuroscience. 56:384-392
On retinal ganglion cells (RGCs) transmit light encoded information to the brain and receive excitatory input from On cone bipolar cells (CBPs). The synaptic CBP input onto On RGCs is mediated by AMPA-type glutamate receptors (AMPARs) that include bo
Publikováno v:
Current Opinion in Neurobiology. 21:328-338
Experience-dependent modifications of neural circuits and function are believed to heavily depend on changes in synaptic efficacy such as LTP/LTD. Hence, much effort has been devoted to elucidating the mechanisms underlying these forms of synaptic pl
Publikováno v:
The Journal of Neuroscience. 27:14326-14337
The trafficking of postsynaptic AMPA receptors (AMPARs) is a powerful mechanism for regulating the strength of excitatory synapses. It has become clear that the surface levels of inhibitory GABAAreceptors (GABAARs) are also subject to regulation and
Autor:
Genoveva Davidkova, Reed C. Carroll
Publikováno v:
The Journal of Neuroscience. 27:13273-13278
The mGluR-dependent endocytosis of AMPA receptors (AMPARs) in the CA1 region is protein synthesis dependent. However, why this form of trafficking, and not that mediated by NMDA receptor activation, is dependent on protein translation is unclear. Her
Publikováno v:
Neuropharmacology. 53:92-100
The activation of NMDA receptors (NMDARs) triggers long-term changes in AMPA receptor-mediated synaptic transmission in the CNS. These long-lasting changes occur via the addition or removal of AMPA receptors (AMPARs) at the synaptic membrane and are
Publikováno v:
Molecular and Cellular Neuroscience. 31:574-585
AMPA receptor (AMPAR) trafficking at CNS synapses is regulated by several receptor-binding proteins. One model of AMPAR endocytosis entails the cotargeting of the GluR2-interacting protein PICK1 and activated PKC to synapses. We demonstrate that NMDA
Retinal ganglion cells (RGCs) receive glutamatergic input from bipolar cells through NMDA- and AMPA-type glutamate receptors. Both GluA2-containing, Ca2+-impermeable AMPA receptors (CI-AMPARs) and GluA2-lacking, Ca2+-permeable AMPA receptors (CP-AMPA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b9f2d1fadc677599b211601a539e2a
https://europepmc.org/articles/PMC3870942/
https://europepmc.org/articles/PMC3870942/
Publikováno v:
Nature Reviews Neuroscience. 2:315-324
Activity-mediated changes in the strength of synaptic communication are important for the establishment of proper neuronal connections during development and for the experience-dependent modification of neural circuitry that is believed to underlie a
Autor:
Wade Morishita, Reed C. Carroll, Hiroki Yasuda, Robert C. Malenka, Eric C. Beattie, Mark von Zastrow, Xiang Yu
Publikováno v:
Nature Neuroscience. 3:1291-1300
The endocytosis of AMPA receptors is thought to be important in the expression of long-term depression (LTD) triggered by NMDA receptor activation. Although signaling pathways necessary for LTD induction have been identified, those responsible for th