Zobrazeno 1 - 10
of 184
pro vyhledávání: '"Reed A. Johnson"'
Autor:
Jaclyn A. Kaiser, Christine E. Nelson, Xueqiao Liu, Hong-Su Park, Yumiko Matsuoka, Cindy Luongo, Celia Santos, Laura R. H. Ahlers, Richard Herbert, Ian N. Moore, Temeri Wilder-Kofie, Rashida Moore, April Walker, Lijuan Yang, Shirin Munir, I-Ting Teng, Peter D. Kwong, Kennichi Dowdell, Hanh Nguyen, JungHyun Kim, Jeffrey I. Cohen, Reed F. Johnson, Nicole L. Garza, Laura E. Via, Daniel L. Barber, Ursula J. Buchholz, Cyril Le Nouën
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Immunization via the respiratory route is predicted to increase the effectiveness of a SARS-CoV-2 vaccine. Here, we evaluate the immunogenicity and protective efficacy of one or two doses of a live-attenuated murine pneumonia virus vector ex
Externí odkaz:
https://doaj.org/article/09d66d03187f4f05a10b4b61eaa3febc
Autor:
Christine E Nelson, Taylor W Foreman, Eduardo R Fukutani, Keith D Kauffman, Shunsuke Sakai, Joel D Fleegle, Felipe Gomez, NIAID/DIR Tuberculosis Imaging Program, Sydnee T Gould, Cyril Le Nouën, Xueqiao Liu, Tracey L Burdette, Nicole L Garza, Bernard A P Lafont, Kelsie Brooks, Cecilia S Lindestam Arlehamn, Daniela Weiskopf, Alessandro Sette, Heather D Hickman, Ursula J Buchholz, Reed F Johnson, Jason M Brenchley, James P Oberman, Artur T L Quieroz, Bruno B Andrade, Laura E Via, Daniel L Barber
Publikováno v:
PLoS Pathogens, Vol 20, Iss 7, p e1012339 (2024)
The regulation of inflammatory responses and pulmonary disease during SARS-CoV-2 infection is incompletely understood. Here we examine the roles of the prototypic pro- and anti-inflammatory cytokines IFNγ and IL-10 using the rhesus macaque model of
Externí odkaz:
https://doaj.org/article/4f2fca22c4d14a298492237eba187e8e
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Omicron emerged following COVID-19 vaccination campaigns, displaced previous SARS-CoV-2 variants of concern worldwide, and gave rise to lineages that continue to spread. Here, we show that Omicron exhibits increased infectivity in primary ad
Externí odkaz:
https://doaj.org/article/9d9e3bf53c4e42d2940807288b7477e3
Autor:
Kerry L. Hilligan, Sivaranjani Namasivayam, Chad S. Clancy, Paul J. Baker, Samuel I. Old, Victoria Peluf, Eduardo P. Amaral, Sandra D. Oland, Danielle O’Mard, Julie Laux, Melanie Cohen, Nicole L. Garza, Bernard A. P. Lafont, Reed F. Johnson, Carl G. Feng, Dragana Jankovic, Olivier Lamiable, Katrin D. Mayer-Barber, Alan Sher
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Type-1 and type-3 interferons (IFNs) are important for control of viral replication; however, less is known about the role of Type-2 IFN (IFNγ) in anti-viral immunity. We previously observed that lung infection with Mycobacterium bovis BCG
Externí odkaz:
https://doaj.org/article/79c3134ea4b5420cb29a8b3a084dbf18
Autor:
Rachel Erickson, Chang Huang, Cameron Allen, Joanna Ireland, Gwynne Roth, Zhongcheng Zou, Jinghua Lu, Bernard A. P. Lafont, Nicole L. Garza, Beniah Brumbaugh, Ming Zhao, Motoshi Suzuki, Lisa Olano, Joseph Brzostowski, Elizabeth R. Fischer, Homer L. Twigg, Reed F. Johnson, Peter D. Sun
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Severe COVID-associated lung injury is a major confounding factor of hospitalizations and death with no effective treatments. Here, we describe a non-classical fibrin clotting mechanism mediated by SARS-CoV-2 infected primary lung but not ot
Externí odkaz:
https://doaj.org/article/dfb1e8c9aa3047e59958ec0f9d7a69ea
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Exposure to agrochemical sprays containing pesticides and tank-mix adjuvants has been implicated in post-bloom mortality, particularly of brood, in honey bee colonies brought into California almond orchards for pollination. Although adjuvant
Externí odkaz:
https://doaj.org/article/ddec357c3a2c4441bc64073951b721a5
Autor:
Jaclyn A. Kaiser, Xueqiao Liu, Cindy Luongo, Yumiko Matsuoka, Celia Santos, Lijuan Yang, Richard Herbert, Ashley Castens, David W. Dorward, Reed F. Johnson, Hong-Su Park, Sharmin Afroz, Shirin Munir, Cyril Le Nouën, Ursula J. Buchholz
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108490- (2023)
Summary: Next-generation SARS-CoV-2 vaccines are needed that induce systemic and mucosal immunity. Murine pneumonia virus (MPV), a murine homolog of respiratory syncytial virus, is attenuated by host-range restriction in nonhuman primates and has a t
Externí odkaz:
https://doaj.org/article/cbf4d88789d345baa457b5b0e0bb1922
Autor:
Paul J. Baker, Eduardo P. Amaral, Ehydel Castro, Andrea C. Bohrer, Flor Torres-Juárez, Cassandra M. Jordan, Christine E. Nelson, Daniel L. Barber, Reed F. Johnson, Kerry L. Hilligan, Katrin D. Mayer-Barber
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Viral co-infections have been implicated in worsening tuberculosis (TB) and during the COVID-19 pandemic, the global rate of TB-related deaths has increased for the first time in over a decade. We and others have previously shown that a resolved prio
Externí odkaz:
https://doaj.org/article/aa860182157d490ab75ea3b2fb208919
Autor:
Xueqiao Liu, Hong-Su Park, Yumiko Matsuoka, Celia Santos, Lijuan Yang, Cindy Luongo, Ian N Moore, Reed F Johnson, Nicole L Garza, Peng Zhang, Paolo Lusso, Sonja M Best, Ursula J Buchholz, Cyril Le Nouën
Publikováno v:
PLoS Pathogens, Vol 19, Iss 6, p e1011057 (2023)
The pediatric live-attenuated bovine/human parainfluenza virus type 3 (B/HPIV3)-vectored vaccine expressing the prefusion-stabilized SARS-CoV-2 spike (S) protein (B/HPIV3/S-2P) was previously evaluated in vitro and in hamsters. To improve its immunog
Externí odkaz:
https://doaj.org/article/eb32882f2f894b40aeab331f51b202e1
Autor:
Jennifer Sword, Ji Hyun Lee, Marcelo A. Castro, Jeffrey Solomon, Nina Aiosa, Syed M. S. Reza, Winston T. Chu, Joshua C. Johnson, Christopher Bartos, Kurt Cooper, Peter B. Jahrling, Reed F. Johnson, Claudia Calcagno, Ian Crozier, Jens H. Kuhn, Lisa E. Hensley, Irwin M. Feuerstein, Venkatesh Mani
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Marburg virus (MARV) is a highly virulent zoonotic filovirid that causes Marburg virus disease (MVD) in humans. The pathogenesis of MVD remains poorly understood, partially due to the low number of cases that can be studied, the absence of s
Externí odkaz:
https://doaj.org/article/56c1f92e128642cca1baf58ff48cf89f