Výsledky vyhledávání

A Novel Inhibitor of Cyclin-Cdk Activity Detected in Transforming Growth Factor β-Arrested Epithelial Cells

Autor: Slingerland, J M, Hengst, L, Pan, C H, Alexander, D, Stampfer, M R, Reed, S I

Publikováno v: Molecular and Cellular Biology. 14:3683-3694

Transforming growth factor beta (TGF-beta) is a potent inhibitor of epithelial cell growth. Cyclins E and A in association with Cdk2 have been shown to play a role in the G1-to-S phase transition in mammalian cells. We have studied the effects of TGF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c2a0165437c8d57e421b3dfb4aaeb4
https://doi.org/10.1128/mcb.14.6.3683-3694.1994

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Mutations in Cell Division Cycle Genes CDC36 and CDC39 Activate the Saccharomyces cerevisiae Mating Pheromone Response Pathway

Autor: de Barros Lopes, M, Ho, J Y, Reed, S I

Publikováno v: Molecular and Cellular Biology. 10:2966-2972

Conditional mutations in the genes CDC36 and CDC39 cause arrest in the G1 phase of the Saccharomyces cerevisiae cell cycle at the restrictive temperature. We present evidence that this arrest is a consequence of a mutational activation of the mating

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce156ec6aa900933af6bcc5df48482a4
https://doi.org/10.1128/mcb.10.6.2966-2972.1990

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Akademický článek

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A pathway in the yeast cell division cycle linking protein kinase C (Pkc1) to activation of Cdc28 at START

Autor: Marini, N J, Meldrum, E, Buehrer, B, Hubberstey, A V, Stone, D E, Traynor-Kaplan, A, Reed, S I

In an effort to study further the mechanism of Cdc28 function and cell cycle commitment, we describe here a genetic approach to identify components of pathways downstream of the Cdc28 kinase at START by screening for mutations that decrease the effec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b432abfb29fe9f6a33ce76f139f3efdf
https://europepmc.org/articles/PMC450245/

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Akademický článek

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Akademický článek

The Role of p34 Kinases in the G1 to S-Phase Transition.

Autor: Reed, S I

Publikováno v: Annual Review of Cell & Developmental Biology; Nov1992, Vol. 8 Issue 1, p529-561, 33p

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Akademický článek

Immune response to cyclin B1 in hepatocellular carcinoma.

Autor: Covini, G., Chan, E. K., Nishioka, M., Morshed, S. A., Reed, S. I., Tan, E. M.

Publikováno v: Hepatology (02709139); Jan1997, Vol. 25 Issue 1, p75-80, 6p

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The Saccharomyces cerevisiae CKS1 Gene, a Homolog of the Schizosaccharomyces pombe suc1+ Gene, Encodes a Subunit of the Cdc28 Protein Kinase Complex

Autor: Hadwiger, J A, Wittenberg, C, Mendenhall, M D, Reed, S I

Publikováno v: Molecular and Cellular Biology. 9:2034-2041

The Saccharomyces cerevisiae gene CDC28 encodes a protein kinase required for cell cycle initiation. In an attempt to identify genes encoding proteins that interact with the Cdc28 protein kinase, high-copy plasmid suppressors of a temperature-sensiti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20af2fb51d75e2284b1445d16398cc57
https://doi.org/10.1128/mcb.9.5.2034-2041.1989

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Conservation of Function and Regulation within the Cdc28/cdc2 Protein Kinase Family: Characterization of the Human Cdc2Hs Protein Kinase in Saccharomyces cerevisiae

Autor: Wittenberg, C, Reed, S I

Publikováno v: Molecular and Cellular Biology. 9:4064-4068

Whereas the Cdc28 protein kinase of the budding yeast Saccharomyces cerevisiae plays an essential role in cell cycle progression during the G1 interval, a function in the progression from the G2 interval into M phase has been inferred for its homolog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17955f52677db5364b1d2b2cd806c512
https://doi.org/10.1128/mcb.9.9.4064-4068.1989

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