Allogeneic immunity clears latent virus following allogeneic stem cell transplantation in SIV-infected ART-suppressed macaques

Autor: Wu, Helen L., Busman-Sahay, Kathleen, Weber, Whitney C., Waytashek, Courtney M., Boyle, Carla D., Bateman, Katherine B., Reed, Jason S., Hwang, Joseph M., Shriver-Munsch, Christine, Swanson, Tonya, Northrup, Mina, Armantrout, Kimberly, Price, Heidi, Robertson-LeVay, Mitch, Uttke, Samantha, Kumar, Mithra R., Fray, Emily J., Taylor-Brill, Sol, Bondoc, Stephen, Agnor, Rebecca, Junell, Stephanie L., Legasse, Alfred W., Moats, Cassandra, Bochart, Rachele M., Sciurba, Joseph, Bimber, Benjamin N., Sullivan, Michelle N., Dozier, Brandy, MacAllister, Rhonda P., Hobbs, Theodore R., Martin, Lauren D., Panoskaltsis-Mortari, Angela, Colgin, Lois M.A., Siliciano, Robert F., Siliciano, Janet D., Estes, Jacob D., Smedley, Jeremy V., Axthelm, Michael K., Meyers, Gabrielle, Maziarz, Richard T., Burwitz, Benjamin J., Stanton, Jeffrey J., Sacha, Jonah B.

Publikováno v: In Immunity 11 July 2023 56(7):1649-1663

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Suppression of human and simian immunodeficiency virus replication with the CCR5-specific antibody Leronlimab in two species.

Autor: Chang, Xiao L.^1,2 (AUTHOR), Reed, Jason S.¹ (AUTHOR), Webb, Gabriela M.¹ (AUTHOR), Wu, Helen L.¹ (AUTHOR), Le, Jimmy³ (AUTHOR), Bateman, Katherine B.¹ (AUTHOR), Greene, Justin M.¹ (AUTHOR), Pessoa, Cleiton¹ (AUTHOR), Waytashek, Courtney¹ (AUTHOR), Weber, Whitney C.¹ (AUTHOR), Hwang, Joseph¹ (AUTHOR), Fischer, Miranda² (AUTHOR), Moats, Cassandra² (AUTHOR), Shiel, Oriene² (AUTHOR), Bochart, Rachele M.² (AUTHOR), Crank, Hugh² (AUTHOR), Siess, Don² (AUTHOR), Giobbi, Travis² (AUTHOR), Torgerson, Jeffrey² (AUTHOR), Agnor, Rebecca² (AUTHOR)

Publikováno v: PLoS Pathogens. 3/31/2022, Vol. 18 Issue 3, p1-23. 23p.

The human IL-15 superagonist ALT-803 directs SIV-specific CD8+ T cells into B-cell follicles.

Autor: Webb, Gabriela M, Li, Shengbin, Mwakalundwa, Gwantwa, Folkvord, Joy M, Greene, Justin M, Reed, Jason S, Stanton, Jeffery J, Legasse, Alfred W, Hobbs, Theodore, Martin, Lauren D, Park, Byung S, Whitney, James B, Jeng, Emily K, Wong, Hing C, Nixon, Douglas F, Jones, R Brad, Connick, Elizabeth, Skinner, Pamela J, Sacha, Jonah B

Sequestering of latent HIV in follicular helper T cells within B-cell follicles that largely exclude cytotoxic T cells is a major barrier to cellular immune-based approaches to eradicate HIV. Here, we show that the clinical-grade human interleukin-15

Externí odkaz: http://hdl.handle.net/10150/626600
http://arizona.openrepository.com/arizona/handle/10150/626600

Cytomegalovirus Vectors Violate CD8⁺ T Cell Epitope Recognition Paradigms

Autor: Hansen, Scott G., Sacha, Jonah B., Hughes, Colette M., Ford, Julia C., Burwitz, Benjamin J., Scholz, Isabel, Gilbride, Roxanne M., Lewis, Matthew S., Gilliam, Awbrey N., Ventura, Abigail B., Malouli, Daniel, Xu, Guangwu, Richards, Rebecca, Whizin, Nathan, Reed, Jason S., Hammond, Katherine B., Fischer, Miranda, Turner, John M., Legasse, Alfred W., Axthelm, Michael K., Edlefsen, Paul T., Nelson, Jay A., Lifson, Jeffrey D., Früh, Klaus, Picker, Louis J.

Publikováno v: Science, 2013 May . 340(6135), 940-940.

Externí odkaz: http://dx.doi.org/10.1126/science.1237874