Hypofractionated accelerated radiation dose-painting (HARD) improves outcomes in unresected soft-tissue sarcoma.

Autor: Bryant JM; Department of Radiation Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa 33612, FL, USA. Electronic address: John.Bryant@moffitt.org., Mills MN; Department of Radiation Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa 33612, FL, USA., Liveringhouse C; Department of Radiation Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa 33612, FL, USA., Palm R; Department of Radiation Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa 33612, FL, USA., Druta M; Department of Sarcoma, H. Lee Moffitt Cancer Center and Research Institute, Tampa 33612, FL, USA., Brohl A; Department of Sarcoma, H. Lee Moffitt Cancer Center and Research Institute, Tampa 33612, FL, USA., Reed DR; Department of Sarcoma, H. Lee Moffitt Cancer Center and Research Institute, Tampa 33612, FL, USA., Johnstone PA; Department of Radiation Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa 33612, FL, USA., Miller JT; Department of Radiation Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa 33612, FL, USA., Latifi K; Department of Radiation Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa 33612, FL, USA., Feygelman V; Department of Radiation Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa 33612, FL, USA., Yang GQ; Department of Radiation Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa 33612, FL, USA., Naghavi AO; Department of Radiation Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa 33612, FL, USA. Electronic address: Arash.Naghavi@moffitt.org.

Publikováno v: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology [Radiother Oncol] 2024 Nov 19, pp. 110644. Date of Electronic Publication: 2024 Nov 19.

MrgprA3 neurons drive cutaneous immunity against helminths through selective control of myeloid-derived IL-33.

Autor: Inclan-Rico JM; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA., Napuri CM; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA., Lin C; Monell Chemical Senses Center, Philadelphia, PA, USA., Hung LY; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA., Ferguson AA; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA., Liu X; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA., Wu Q; Department of Neuroscience, School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Pastore CF; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA., Stephenson A; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA., Femoe UM; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA., Musaigwa F; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA., Rossi HL; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA., Freedman BD; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA., Reed DR; Monell Chemical Senses Center, Philadelphia, PA, USA., Macháček T; Department of Parasitology, Faculty of Science, Charles University, Prague, Czech Republic., Horák P; Department of Parasitology, Faculty of Science, Charles University, Prague, Czech Republic., Abdus-Saboor I; Department of Biological Sciences, Zuckerman Mind, Brain, Behavior Institute, Columbia University, New York, NY, USA., Luo W; Department of Neuroscience, School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Institute for Regenerative Medicine, School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Herbert DR; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA. debroski@vet.upenn.edu.

Publikováno v: Nature immunology [Nat Immunol] 2024 Nov; Vol. 25 (11), pp. 2068-2084. Date of Electronic Publication: 2024 Oct 01.

Poverty, race, ethnicity, and survival in pediatric nonmetastatic osteosarcoma: a Children's Oncology Group report.

Autor: Ilcisin L; Department of Pediatric Oncology, Division of Population Sciences, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA, USA.; Department of Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Han R; Children's Oncology Group, Monrovia, CA, USA., Krailo M; Children's Oncology Group, Arcadia, CA, USA.; Department of Population and Public Health Sciences Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Shulman DS; Department of Pediatric Oncology, Division of Population Sciences, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA, USA., Weil BR; Department of Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Weldon CB; Department of Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Umaretiya P; Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA., Aziz-Bose R; Department of Pediatric Oncology, Division of Population Sciences, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA, USA., Greenzang KA; Department of Pediatric Oncology, Division of Population Sciences, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA, USA., Gorlick R; Division of Pediatrics, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Reed DR; Division of Pediatric Solid Tumors, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Randall RL; Department of Orthopaedic Surgery, University of California Davis Health, Sacramento, CA, USA., Nadel H; Division of Radiology, Lucille Packard Children's Hospital at Stanford University, Stanford, CA, USA., Binitie O; Department of Surgery, Moffitt Cancer Center, Tampa, FL, USA., Dubois SG; Department of Pediatric Oncology, Division of Population Sciences, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA, USA., Janeway KA; Department of Pediatric Oncology, Division of Population Sciences, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA, USA., Bona K; Department of Pediatric Oncology, Division of Population Sciences, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA, USA.

Publikováno v: Journal of the National Cancer Institute [J Natl Cancer Inst] 2024 Oct 01; Vol. 116 (10), pp. 1664-1674.

Pediatric Leukemia Roadmaps Are a Guide for Positive Metastatic Bone Sarcoma Trials.

Autor: Reed DR; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Tulpule A; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY., Metts J; Johns Hopkins All Children's Hospital, St Petersburg, FL., Trucco M; Cleveland Clinic Children's Hospital, Cleveland, OH., Robertson-Tessi M; Integrated Mathematical Oncology Department, Moffitt Cancer Center, Tampa, FL., O'Donohue TJ; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY., Iglesias-Cardenas F; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY., Isakoff MS; Connecticut Children's Medical Center, Hartford, CT., Mauguen A; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY., Shukla N; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY., Dela Cruz FS; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY., Tap W; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Kentsis A; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY., Morris CD; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY., Hameed M; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY., Honeyman JN; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY., Behr GG; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY., Sulis ML; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY., Ortiz MV; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY., Slotkin E; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY.

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2024 Sep 01; Vol. 42 (25), pp. 2955-2960. Date of Electronic Publication: 2024 Jun 06.

Looking ahead to CD3, T-cell engager bispecific antibodies for hematological malignancies.

Autor: Reed DR; Department of Medicine, Division of Hematology and Oncology, University of Virginia Comprehensive Cancer Center, Charlottesville, VA, USA., Lum LG; Department of Medicine, Division of Hematology and Oncology, University of Virginia Comprehensive Cancer Center, Charlottesville, VA, USA.

Publikováno v: Expert opinion on biological therapy [Expert Opin Biol Ther] 2024 Aug; Vol. 24 (8), pp. 761-772. Date of Electronic Publication: 2024 Jul 29.