Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Reeba K Vikramadithyan"'
Autor:
Masayoshi Yokoyama, Toru Seo, Taesik Park, Hiroaki Yagyu, Yunying Hu, Ni Huiping Son, Ayanna S. Augustus, Reeba K. Vikramadithyan, Rajasekhar Ramakrishnan, Leslie K. Pulawa, Robert H. Eckel, Ira J. Goldberg
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 3, Pp 646-655 (2007)
Regulation of cholesterol metabolism in cultured cells and in the liver is dependent on actions of the LDL receptor. However, nonhepatic tissues have multiple pathways of cholesterol uptake. One possible pathway is mediated by LPL, an enzyme that pri
Externí odkaz:
https://doaj.org/article/73b75d3edfd34bc78433795ee5c6f423
Autor:
Reeba K. Vikramadithyan, Yuko Kako, Guangping Chen, Yunying Hu, Eri Arikawa-Hirasawa, Yoshihiko Yamada, Ira J. Goldberg
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 10, Pp 1806-1812 (2004)
The hypothesis that lipoprotein association with perlecan is atherogenic was tested by studying atherosclerosis in mice that had a heterozygous deletion of perlecan, the primary extracellular heparan sulfate proteoglycan in arteries. We first studied
Externí odkaz:
https://doaj.org/article/368ef67b118d49deb9fb48db241ae4e8
Autor:
Mahesh Paschapur, Jeffrey M. Brown, Tanmaya Bastia, Lawrence R. Marcin, Jayakumar Sankara Warrier, Srinivasan Thangathirupathy, Joanne J. Bronson, Raja Reddy Kallem, Huiping Zhang, Jyoti Gulia, Alda Fernandes, Digavalli V. Sivarao, Deborah Keavy, Amy Newton, Jianqing Li, Pattipati S. Naidu, Kuchibhotla Vijaya Kumar, James Kempson, Michael R. Weed, Rick L. Pieschl, Mark Bookbinder, Charlie F. Albright, Kimberly Newberry, Yu-Wen Li, Dalton King, Manjunath Ramarao, Jean Simmermacher, Linda J. Bristow, Meenakshee Sinha, Eric Shields, Lorin A. Thompson, John E. Macor, Charulatha Sanmathi, Imadul Islam, B.N. Srikumar, Richard E. Olson, John D. Graef, Arvind Mathur, Narasimharaju Kalidindi, Joseph Polino, Michael Sinz, Thaddeus F. Molski, Jayant Aher, Reeba K. Vikramadithyan
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 363:377-393
(R)-3-((3S,4S)-3-fluoro-4-(4-hydroxyphenyl)piperidin-1-yl)-1-(4-methylbenzyl)pyrrolidin-2-one (BMS-986169) and the phosphate prodrug 4-((3S,4S)-3-fluoro-1-((R)-1-(4-methylbenzyl)-2-oxopyrrolidin-3-yl)piperidin-4-yl)phenyl dihydrogen phosphate (BMS-98
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fc12be7607ec5d5401f625fdca24cd2
https://doi.org/10.1124/jpet.117.242784
https://doi.org/10.1124/jpet.117.242784
Autor:
Justin Vijay Louis, Kumaran Dandapani, Susheel J. Nara, Yang Hong, Yung Tian, Sarat Kumar Sarvasiddhi, Yifeng Lu, Carolyn Diane Dzierba, Walter Kostich, Yu-Wen Li, Rick L. Pieschl, Sreenivasulu Naidu, Charlie F. Albright, Joanne J. Bronson, John E. Macor, Reeba K. Vikramadithyan
Publikováno v:
Neuropharmacology. 118:167-174
Adaptor-associated kinase 1 (AAK1), a member of the Ark1/Prk1 family of serine/threonine kinases, plays a role in modulating clatherin coated endocytosis of specific surface receptors. We have demonstrated that AAK1 inhibitors are efficacious in rode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f168813c715e6b8c8865371b20f68a5c
https://doi.org/10.1016/j.neuropharm.2017.03.015
https://doi.org/10.1016/j.neuropharm.2017.03.015
Autor:
James E. Grace, Brian Zambrowicz, Pradeep Vattikundala, Kenneth G. Carson, Jonathan Lippy, Clotilde Bourin, Alan Main, Alan Wilson, Sreenivasulu Naidu, Sandhya Mandlekar, Carolyn Diane Dzierba, Saravanan Elavazhagan, Walter Kostich, Gauri Shankar, Jeffrey M. Brown, Charles M. Conway, Charles F. Albright, Justin Vijay Louis, Yu-Wen Li, Vivek Sharma, Yanling Huang, Laszlo Kiss, Amr Nouraldeen, Susheel J. Nara, Martin A. Lewis, Ryan Westphal, Vinay K. Holenarsipur, Anand Balakrishnan, Amy Easton, Robert Zaczek, Jonathan C. Swaffield, Ted Molski, Rick L. Pieschl, Kevin Baker, Katerina Savelieva, Yingzhi Bi, Kenneth S. Santone, Linda J. Bristow, John E. Macor, Jianlin Feng, Guilan Ye, Joanne J. Bronson, Manish Lal Das, Reeba K. Vikramadithyan, Kevin O’Malley, Jason W. Allen, Brian D. Hamman, Michael Gulianello, Yifeng Lu, Thomas H. Lanthorn, Kimberley A. Lentz, Anoop Kumar, Manoj Dokania, Kumaran Dandapani, Rex Denton
Publikováno v:
The Journal of Pharmacology and Experimental Therapeutics
To identify novel targets for neuropathic pain, 3097 mouse knockout lines were tested in acute and persistent pain behavior assays. One of the lines from this screen, which contained a null allele of the adapter protein-2 associated kinase 1 (AAK1) g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04b1480bd30607a9fe64d0e01fbd6b27
http://europepmc.org/articles/PMC4998676
http://europepmc.org/articles/PMC4998676
Autor:
Durga Shiva Prasad, Rick L. Pieschl, Yu-Wen Li, Siva Subramani, Muppana V. Sreedhara, Shailesh Dudhgaonkar, B.N. Srikumar, Reeba K. Vikramadithyan, Ratika Srivastava, Manish Lal Das, Justin Vijay Louis, Narasimharaju Kalidindi, Mahesh Paschapur, Bharath Adepu, Manjunath Ramarao, Pattipati S. Naidu, Linda J. Bristow, Vijaya K. Kuchibhotla, Jignesh Nagar
Publikováno v:
Journal of psychopharmacology (Oxford, England). 33(1)
Background: A significant proportion of patients suffering from major depression fail to remit following treatment and develop treatment-resistant depression. Developing novel treatments requires animal models with good predictive validity. MRL/lpr m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a9d4dcf1d509283d7a23a4993aa30fe
https://pubmed.ncbi.nlm.nih.gov/30484737
https://pubmed.ncbi.nlm.nih.gov/30484737
Autor:
Arvind Mathur, Rajareddy Kallem, Thaddeus F. Molski, Manjunatha Narayana Rao Kamble, Michelle Nophsker, Huiping Zhang, Murali Subramanian, Dalton King, Linda J. Bristow, Lawrence R. Marcin, B.N. Srikumar, Grandhi Venkat Ram Krishna Mohan Gupta, Kumar Kuchibhotla Vijaya, Jayakumar Sankara Warrier, Michael Sinz, Charulatha Sanmathi, G. Nagaraju, Xiaoliang Zhuo, Raju Mannoori, Imadul Islam, Alicia Ng, Pattipati S. Naidu, Eric Shields, Joanne J. Bronson, Narasimharaju Kalidindi, Reeba K. Vikramadithyan, Gopikishan Tonukunuru, Lorin A. Thompson, James Kempson, Srinivasan Thangathirupathy, Jogi Srinivas, Bradley C. Pearce, Jyoti Gulia, Jean Simmermacher, Srinivas Cheruku, Mahesh Paschapur, Jianliang Shi, John E. Macor, Jayant Aher, Manjunath Ramarao, Charlie F. Albright, Richard E. Olson, Rex Denton, Aliphedi B. Reddy, Hyunsoo Park, Karageorge George N, Tanmaya Bastia, Jianqing Li
Publikováno v:
ACS medicinal chemistry letters. 9(5)
[Image: see text] There is a significant unmet medical need for more efficacious and rapidly acting antidepressants. Toward this end, negative allosteric modulators of the N-methyl-d-aspartate receptor subtype GluN2B have demonstrated encouraging the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70b5b1329a3adeaa60f04b63eb061394
https://pubmed.ncbi.nlm.nih.gov/29795762
https://pubmed.ncbi.nlm.nih.gov/29795762
Autor:
Bettadapura N Srikumar, Pattipati S Naidu, Narasimharaju Kalidindi, Paschapur, Mahesh, Bharath Adepu, Subramani, Siva, Jignesh Nagar, Ratika Srivastava, Muppana V Sreedhara, Durga Shiva Prasad, Das, Manish Lal, Louis, Justin V, Kuchibhotla, Vijaya K, Shailesh Dudhgaonkar, Pieschl, Rick L, Li, Yu-Wen, Bristow, Linda J, Manjunath Ramarao, Reeba K Vikramadithyan
Supplemental material, JOP812102_supplemental_material for Diminished responses to monoaminergic antidepressants but not ketamine in a mouse model for neuropsychiatric lupus by Bettadapura N Srikumar, Pattipati S Naidu, Narasimharaju Kalidindi, Mahes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ef8c48b5d9717876d76215da49b1877
Autor:
Linda J, Bristow, Jyoti, Gulia, Michael R, Weed, Bettadapura N, Srikumar, Yu-Wen, Li, John D, Graef, Pattipati S, Naidu, Charulatha, Sanmathi, Jayant, Aher, Tanmaya, Bastia, Mahesh, Paschapur, Narasimharaju, Kalidindi, Kuchibhotla Vijaya, Kumar, Thaddeus, Molski, Rick, Pieschl, Alda, Fernandes, Jeffrey M, Brown, Digavalli V, Sivarao, Kimberly, Newberry, Mark, Bookbinder, Joseph, Polino, Deborah, Keavy, Amy, Newton, Eric, Shields, Jean, Simmermacher, James, Kempson, Jianqing, Li, Huiping, Zhang, Arvind, Mathur, Raja Reddy, Kallem, Meenakshee, Sinha, Manjunath, Ramarao, Reeba K, Vikramadithyan, Srinivasan, Thangathirupathy, Jayakumar, Warrier, Imadul, Islam, Joanne J, Bronson, Richard E, Olson, John E, Macor, Charlie F, Albright, Dalton, King, Lorin A, Thompson, Lawrence R, Marcin, Michael, Sinz
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 363(3)
(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fd1b2a02de8ae2373f7595e246bd87cd
https://pubmed.ncbi.nlm.nih.gov/28954811
https://pubmed.ncbi.nlm.nih.gov/28954811
Autor:
Robert H. Eckel, Hiroaki Yagyu, Tae-Sik Park, Ayanna S. Augustus, Reeba K. Vikramadithyan, Rajasekhar Ramakrishnan, Ira J. Goldberg, Masayoshi Yokoyama, Leslie K. Pulawa, Ni Huiping Son, Yunying Hu, Toru Seo
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 3, Pp 646-655 (2007)
Regulation of cholesterol metabolism in cultured cells and in the liver is dependent on actions of the LDL receptor. However, nonhepatic tissues have multiple pathways of cholesterol uptake. One possible pathway is mediated by LPL, an enzyme that pri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::810b70697a0625eb2c3c61ad324fb66b
https://doi.org/10.1194/jlr.m600301-jlr200
https://doi.org/10.1194/jlr.m600301-jlr200