Mutations in HNF1A Result in Marked Alterations of Plasma Glycan Profile:Diabetes

Autor: Thanabalasingham, G., Huffman, J. E., Kattla, J. J., Novokmet, M., Rudan, I., Gloyn, A. L., Hayward, C., Adamczyk, B., Reynolds, R. M., Muzinic, A., Hassanali, N., Pucic, M., Bennett, A. J., Essafi, A., Polasek, O., Mughal, S. A., Redzic, I., Primorac, D., Zgaga, L., Kokic, I., Hansen, T., Gasperikova, D., Tjora, E., Strachan, M. W. J., Nielsen, T., Stanik, J., Klimes, I., Pedersen, O. B., Njolstad, P. R., Wild, S. H., Gyllensten, U., Gornik, O., Wilson, J. F., Hastie, N. D., Campbell, H., McCarthy, M. I., Rudd, P. M., Owen, K. R., Lauc, G., Wright, A. F.

Publikováno v: Thanabalasingham, G, Huffman, J E, Kattla, J J, Novokmet, M, Rudan, I, Gloyn, A L, Hayward, C, Adamczyk, B, Reynolds, R M, Muzinic, A, Hassanali, N, Pucic, M, Bennett, A J, Essafi, A, Polasek, O, Mughal, S A, Redzic, I, Primorac, D, Zgaga, L, Kokic, I, Hansen, T, Gasperikova, D, Tjora, E, Strachan, M W J, Nielsen, T, Stanik, J, Klimes, I, Pedersen, O B, Njolstad, P R, Wild, S H, Gyllensten, U, Gornik, O, Wilson, J F, Hastie, N D, Campbell, H, McCarthy, M I, Rudd, P M, Owen, K R, Lauc, G & Wright, A F 2013, ' Mutations in HNF1A Result in Marked Alterations of Plasma Glycan Profile : Diabetes ', Diabetes, vol. 62, pp. 1329-1337 . https://doi.org/10.2337/db12-0880

A recent genome-wide association study identified hepatocyte nuclear factor 1-alpha (HNF1A) as a key regulator of fucosylation. We hypothesized that loss-of-function HNF1A mutations causal for maturity-onset diabetes of the young (MOD?) would display

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3062::f94e7026e3aba58168034eedc34ece2b
https://portal.findresearcher.sdu.dk/da/publications/893eea28-3feb-459a-bddc-0c22186bb4c8

Autoimmune hepatitis displays distinctively high multi-antennary sialylation on plasma N-glycans compared to other liver diseases.

Autor: Pongracz, Tamas¹ (AUTHOR), Biewenga, Maaike² (AUTHOR), Stoelinga, Anna Eva Charlotte² (AUTHOR), Bladergroen, Marco René¹ (AUTHOR), Nicolardi, Simone¹ (AUTHOR), Trouw, Leendert Adrianus³ (AUTHOR), Wuhrer, Manfred¹ (AUTHOR), de Haan, Noortje¹ (AUTHOR) n.de_haan@lumc.nl, van Hoek, Bart² (AUTHOR)

Publikováno v: Journal of Translational Medicine. 5/14/2024, Vol. 22 Issue 1, p1-12. 12p.

Altered microheterogeneity at several N‐glycosylation sites in OPSCC in constant protein expression conditions.

Autor: Dickinson, Amy^1,2 (AUTHOR) amy.dickinson@helsinki.fi, Joenväärä, Sakari^3,4 (AUTHOR), Tohmola, Tiialotta^3,4 (AUTHOR), Renkonen, Jutta³ (AUTHOR), Mattila, Petri¹ (AUTHOR), Carpén, Timo^1,2,5 (AUTHOR), Mäkitie, Antti^1,2,6 (AUTHOR), Silén, Suvi^1,2 (AUTHOR)

Publikováno v: FASEB Bioadvances. Jan2024, Vol. 6 Issue 1, p26-39. 14p.

Age-Related Changes in the Temperature of the Lumbar Spine Measured by Passive Microwave Radiometry (MWR).

Autor: Tarakanov, Alexander V.¹ (AUTHOR) dr-tarakanov@yandex.ru, Tarakanov, Alexander A.¹ (AUTHOR) scenar.neuro@gmail.com, Skorodumova, Elizaveta G.² (AUTHOR) lisavetta91@mail.ru, Roberts, Neil³ (AUTHOR) neil.roberts@ed.ac.uk, Kobayshi, Toshi⁴ (AUTHOR) binsei.nd@gmail.com, Vesnin, Sergey G.⁴ (AUTHOR) vesnin47@gmail.com, Zelman, Vladimir⁵ (AUTHOR) vzelman@usc.edu, Goryanin, Igor^6,7 (AUTHOR) goryanin@ed.ac.uk

Publikováno v: Diagnostics (2075-4418). Nov2023, Vol. 13 Issue 21, p3294. 12p.

Fc-Engineered Therapeutic Antibodies: Recent Advances and Future Directions.

Autor: Abdeldaim, Dalia T.^1,2 (AUTHOR) abdeldaim@hochschule-bc.de, Schindowski, Katharina¹ (AUTHOR) schindowski@hochschule-bc.de

Publikováno v: Pharmaceutics. Oct2023, Vol. 15 Issue 10, p2402. 24p.