Zobrazeno 1 - 10
of 357
pro vyhledávání: '"Reduction-responsive"'
Autor:
Yuhuan Li, Xin Wang, Yu Gao, Ziyi Zhang, Te Liu, Zhuo Zhang, Yinan Wang, Fei Chang, Modi Yang
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Rheumatoid arthritis (RA) involves chronic inflammation, oxidative stress, and complex immune cell interactions, leading to joint destruction. Traditional treatments are often limited by off-target effects and systemic toxicity. This study i
Externí odkaz:
https://doaj.org/article/b08394766d7c4e3a9a4364cb54f356cd
Publikováno v:
Bioactive Materials, Vol 17, Iss , Pp 320-333 (2022)
Ischemia-reperfusion (IR) injury represents a major cause of myocardial dysfunction after infarction and thrombolytic therapy, and it is closely related to the free radical explosion and overwhelming inflammatory responses. Herein, macrophage-targeti
Externí odkaz:
https://doaj.org/article/fdada927d6b149b1b443698380c6112e
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Powerful chemotherapeutics have been used to combat tumor cells, but serious adverse effects and poor therapeutic efficiency restrict their clinical performance. Herein, we developed reduction-responsive supramolecular hybridized paclitaxel nanoparti
Externí odkaz:
https://doaj.org/article/6038bfab9b814ccc8c99aabc3e420c83
Akademický článek
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Autor:
Yun Yang, Danrong Hu, Yi Lu, Bingyang Chu, Xinlong He, Yu Chen, Yao Xiao, Chengli Yang, Kai Zhou, Liping Yuan, Zhiyong Qian
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 6, Pp 2710-2730 (2022)
Breast cancer has become the most commonly diagnosed cancer type in the world. A combination of chemotherapy and photothermal therapy (PTT) has emerged as a promising strategy for breast cancer therapy. However, the intricacy of precise delivery and
Externí odkaz:
https://doaj.org/article/3ccdf2a4ea1142ad953da36fce7554a4
Publikováno v:
Bioactive Materials, Vol 6, Iss 9, Pp 2894-2904 (2021)
Polymer systems can be designed into different structures and morphologies according to their physical and chemical performance requirements, and are considered as one of the most promising controlled delivery systems that can effectively improve the
Externí odkaz:
https://doaj.org/article/71442788c4fe4e8abf3fe7ba7a789ac4
Autor:
Trung Thang Vu, Sonyabapu Yadav, Obireddy Sreekanth Reddy, Sung-Han Jo, Soo-Bin Joo, Byeong Kook Kim, Eun Ju Park, Sang-Hyug Park, Kwon Taek Lim
Publikováno v:
Pharmaceuticals, Vol 16, Iss 6, p 841 (2023)
Selective delivery of anticancer drug molecules to the tumor site enhances local drug dosages, which leads to the death of cancer cells while simultaneously minimizing the negative effects of chemotherapy on other tissues, thereby improving the patie
Externí odkaz:
https://doaj.org/article/1b043492e8cd40919b8c08a80a3cbd70
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Although great progress has been made in improving the efficacy of cancer treatment through combination treatment using drug agents, there are still challenges in improving the efficiency of drug delivery. In this study, olaparib and doxorubicin were
Externí odkaz:
https://doaj.org/article/6d265bcb41074a80b880ffe0f86c8f1b
Autor:
Yi Feng, Hanxi Zhang, Xiaoxue Xie, Yu Chen, Geng Yang, Xiaodan Wei, Ningxi Li, Mengyue Li, Tingting Li, Xiang Qin, Shun Li, Fengming You, Chunhui Wu, Hong Yang, Yiyao Liu
Publikováno v:
Materials Today Bio, Vol 14, Iss , Pp 100288- (2022)
Therapeutic approaches of combining conventional photodynamic therapy (PDT) with other adjuvant treatments to sensitize PDT represent an appealing strategy. Herein, a novel synergetic “nanobomb” strategy based on glutathione (GSH)-responsive biod
Externí odkaz:
https://doaj.org/article/22633344dc794c4f9261b4145664f525
Publikováno v:
Molecules, Vol 28, Iss 9, p 3824 (2023)
In this work, glucose transporter-1 (GLUT-1) and glutathione (GSH) over-expression in liver cancer was utilized to design a reduction-responsive and active targeting drug delivery system AG-PEG-SS-PCL (APSP) for the delivery of sorafenib (SF). The SF
Externí odkaz:
https://doaj.org/article/0c5fa80e242b4f37ae38fd0a88c73092