Zobrazeno 1 - 10
of 485
pro vyhledávání: '"Redox stress"'
Autor:
Basiru Olaitan Ajiboye, Courage Dele Famusiwa, Monsurah Oluwaseyifunmi Amuda, Stephen Oluwaseun Afolabi, Benjamin Temidayo Ayotunde, Adedeji A. Adejumo, Ajoke Fehintola Idayat Akindele, Babatunji Emmanuel Oyinloye, Olutunmise Victoria Owolabi, Claudia Genovese, Oluwafemi Adeleke Ojo
Publikováno v:
Biochemistry and Biophysics Reports, Vol 38, Iss , Pp 101735- (2024)
Diabetes is a group of medical conditions characterized by the body's inability to effectively control blood glucose levels, due to either insufficient insulin synthesis in type 1 diabetes or inadequate insulin sensitivity in type 2 diabetes. Accordi
Externí odkaz:
https://doaj.org/article/3145b69197c44568a0302a5ad5a6a434
Publikováno v:
Antioxidants, Vol 13, Iss 8, p 932 (2024)
The transition metal cadmium (Cd) is toxic to humans and can induce cellular redox stress and inflammation. Cd is a recognized carcinogen, but the molecular mechanisms associated with its genotoxicity and carcinogenicity are not defined. Therefore, a
Externí odkaz:
https://doaj.org/article/e5dd1177ffca426babe2fd8a340b9937
Publikováno v:
Antioxidants, Vol 13, Iss 8, p 1006 (2024)
Activation of Nrf2—the master regulator of antioxidative response—at different stages of embryonic development has been shown to result in changes in gene expression, but the tissue-specific and downstream effects of Nrf2 activation during develo
Externí odkaz:
https://doaj.org/article/045e857eb5784868af16a4e3ed10d3b0
Autor:
Matthew Myles, Heba Barnawi, Mahmoud Mahmoudpour, Sargon Shlimon, Adrienne Chang, Daniel Zimmermann, Chiwon Choi, Najwa Zebian, Carole Creuzenet
Publikováno v:
MicrobiologyOpen, Vol 13, Iss 1, Pp n/a-n/a (2024)
Abstract Campylobacter jejuni is a commensal in many animals but causes diarrhea in humans. Its polysaccharide capsule contributes to host colonization and virulence in a strain‐ and model‐specific manner. We investigated if the capsule and its h
Externí odkaz:
https://doaj.org/article/a3fca20b013f42f591b80ca2e47009de
Autor:
Marco Bauzá-Thorbrügge, Eduard Peris, Shabnam Zamani, Peter Micallef, Alexandra Paul, Stefano Bartesaghi, Anna Benrick, Ingrid Wernstedt Asterholm
Publikováno v:
Redox Biology, Vol 68, Iss , Pp 102951- (2023)
White adipose tissue browning, defined by accelerated mitochondrial metabolism and biogenesis, is considered a promising mean to treat or prevent obesity-associated metabolic disturbances. We hypothesize that redox stress acutely leads to increased p
Externí odkaz:
https://doaj.org/article/61b774a4c0b54b2993fdc76ddce133b4
Publikováno v:
Biomedicines, Vol 12, Iss 3, p 505 (2024)
Mefloquine (MQ) is a quinoline-based anti-malarial drug used for chemoprophylaxis or as a treatment in combination with artesunate. Although MQ has clear anti-Plasmodium falciparum properties, it can induce neurotoxicity and undesired neuropsychiatri
Externí odkaz:
https://doaj.org/article/d9f07d5516424c9d994058486121e2ab
Autor:
Gracious Yoofi Donkor, Greg M. Anderson, Michael Stadler, Patrick Ofori Tawiah, Carl D. Orellano, Kevin A. Edwards, Jan-Ulrik Dahl
Publikováno v:
mSphere, Vol 8, Iss 5 (2023)
ABSTRACT The rapid dissemination of antibiotic resistance combined with the decline in the discovery of novel antibiotics represents a major challenge for infectious disease control that can only be mitigated by investments in novel treatment strateg
Externí odkaz:
https://doaj.org/article/8badd1d2f3f64858a8c8fdb70ae499c2
Autor:
Daniel N. El Kodsi, Jacqueline M. Tokarew, Rajib Sengupta, Nathalie A. Lengacher, Ajanta Chatterji, Angela P. Nguyen, Heather Boston, Qiubo Jiang, Carina Palmberg, Chantal Pileggi, Chet E. Holterman, Bojan Shutinoski, Juan Li, Travis K. Fehr, Matthew J. LaVoie, Rajiv R. Ratan, Gary S. Shaw, Masashi Takanashi, Nobutaka Hattori, Christopher R. Kennedy, Mary-Ellen Harper, Arne Holmgren, Julianna J. Tomlinson, Michael G. Schlossmacher
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-21 (2023)
Abstract We recently discovered that the expression of PRKN, a young-onset Parkinson disease-linked gene, confers redox homeostasis. To further examine the protective effects of parkin in an oxidative stress model, we first combined the loss of prkn
Externí odkaz:
https://doaj.org/article/a0cf0ed0ee2143f0a980d7d5a5c6d50a
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