Zobrazeno 1 - 10
of 4 695
pro vyhledávání: '"Redox Homeostasis"'
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Triple-negative breast cancer (TNBC) is an aggressive cancer type that lacks targeted treatment options. Ferroptosis, a novel therapeutic strategy, induces cell death by disrupting the oxidative-reductive balance. Hesperetin, a potential TNB
Externí odkaz:
https://doaj.org/article/c53ebeb7def7433b8a6d320e9d34c382
Autor:
Leonardo Schirone, Maria Carla Di Paolo, Daniele Vecchio, Cristina Nocella, Alessandra D’Amico, Riccardo Urgesi, Lorella Pallotta, Gianfranco Fanello, Giuseppe Villotti, Maria Giovanna Graziani, Mariangela Peruzzi, Elena De Falco, Roberto Carnevale, Sebastiano Sciarretta, Giacomo Frati, Cristiano Pagnini
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract In this pilot study, we assessed the role of autophagy in Crohn’s Disease (CD), particularly in patients with a stenosing phenotype. Through the analysis of biopsied specimens from 36 patients, including 11 controls and 25 CD patients, cat
Externí odkaz:
https://doaj.org/article/3aeed55b3fd74bc9b75a7bbd123b9beb
Autor:
Yao Liu, Aimin Wu, Bing Yu, Jun He, Jie Yu, Xiangbing Mao, Ping Zheng, Yuheng Luo, Junqiu Luo, Junning Pu, Hui Yan, Daiwen Chen
Publikováno v:
Journal of Animal Science and Biotechnology, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Background Appropriate iron supplementation is essential for neonatal growth and development. However, there are few reports on the effects of iron overload on neonatal growth and immune homeostasis. Thus, the aim of this study was to invest
Externí odkaz:
https://doaj.org/article/f6be4774545f441ea8957fb364525394
Autor:
Zilong Li, Jichen Li, Meng Wu, Zexin Li, Jiawen Zhou, Yunjie Lu, Yong Xu, Lei Qin, Zhiwen Fan
Publikováno v:
Redox Biology, Vol 78, Iss , Pp 103414- (2024)
Liver ischemia-reperfusion (I/R) injury is a clinically relevant pathophysiological process that determines the effectiveness of life-saving liver transplantation, to which aberrant ROS accumulation plays a key role. In the present study we investiga
Externí odkaz:
https://doaj.org/article/465b51ac763c4da5a0a3c1323d4acd03
Autor:
Raheel Shahzad, Putri Widyanti Harlina, Shahid Ullah Khan, Muhammad Ihtisham, Aamir Hamid Khan, Fohad Mabood Husain, Agung Karuniawan
Publikováno v:
Journal of Plant Interactions, Vol 19, Iss 1 (2024)
Rice (Oryza sativa L.) stands out as the world's most vital staple food crop, yet is susceptible to UV-B radiation stress. This study investigates the physiological and transcriptome responses in rice exposed to titanium dioxide nanoparticles (TiO2 N
Externí odkaz:
https://doaj.org/article/112abd49bf224eedbc1fb0bb3aca7cad
Publikováno v:
Plant Signaling & Behavior, Vol 19, Iss 1 (2024)
Plants, as sessile organisms, are subjected to diverse abiotic stresses, including salinity, desiccation, metal toxicity, thermal fluctuations, and hypoxia at different phases of plant growth. Plants can activate messenger molecules to initiate a sig
Externí odkaz:
https://doaj.org/article/58f4d4d0078d48acb197148fd01e6f95
Autor:
Diego De Leon-Oliva, Diego Liviu Boaru, Ana M. Minaya-Bravo, Patricia De Castro-Martinez, Oscar Fraile-Martinez, Cielo Garcia-Montero, David Cobo-Prieto, Silvestra Barrena-Blázquez, Laura Lopez-Gonzalez, Agustín Albillos, Melchor Alvarez-Mon, Miguel A. Saez, Raul Diaz-Pedrero, Miguel A. Ortega
Publikováno v:
Heliyon, Vol 10, Iss 21, Pp e39684- (2024)
In the face of cell damage, cells can initiate a response ranging from survival to death, the balance being crucial for tissue homeostasis and overall health. Cell death, in both accidental and regulated forms, plays a fundamental role in maintaining
Externí odkaz:
https://doaj.org/article/423196c22ecc49cfba6d7000415de14e
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Trisomy 21, characterized by the presence of an additional chromosome 21, leads to a set of clinical features commonly referred to as Down syndrome (DS). The pathological phenotypes observed in DS are caused by a combination of factors, such as mitoc
Externí odkaz:
https://doaj.org/article/cd3aa21f0d284af2a4aceb30be1205d0
Autor:
Zixuan Zhao, Yuan Cao, Rui Xu, Junyue Fang, Yuxuan Zhang, Xiaoding Xu, Linzhuo Huang, Rong Li
Publikováno v:
Smart Materials in Medicine, Vol 5, Iss 2, Pp 291-320 (2024)
Although characterized by high reactive oxygen species (ROS) generation, cancer cells maintain redox homeostasis to avoid severe damage (e.g., DNA, protein, and plasma membrane dysfunction) and facilitate cancer progression. Emerging evidence has ind
Externí odkaz:
https://doaj.org/article/c9a48520b8c540d58bd859b644fdd344