Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Rediet Zewdu"'
Autor:
Rediet Zewdu, Elnaz Mirzaei Mehrabad, Kelley Ingram, Pengshu Fang, Katherine L Gillis, Soledad A Camolotto, Grace Orstad, Alex Jones, Michelle C Mendoza, Benjamin T Spike, Eric L Snyder
Publikováno v:
eLife, Vol 10 (2021)
Cancer cells undergo lineage switching during natural progression and in response to therapy. NKX2-1 loss in human and murine lung adenocarcinoma leads to invasive mucinous adenocarcinoma (IMA), a lung cancer subtype that exhibits gastric differentia
Externí odkaz:
https://doaj.org/article/6480f1d0e1a849568a7cc19f30a0c0d1
Autor:
Karen Handschuh, Jennifer Feenstra, Matthew Koss, Elisabetta Ferretti, Maurizio Risolino, Rediet Zewdu, Michelle A. Sahai, Jean-Denis Bénazet, Xiao P. Peng, Michael J. Depew, Laura Quintana, James Sharpe, Baolin Wang, Heather Alcorn, Roberta Rivi, Stephen Butcher, J. Robert Manak, Thomas Vaccari, Harel Weinstein, Kathryn V. Anderson, Elizabeth Lacy, Licia Selleri
Publikováno v:
Cell Reports, Vol 9, Iss 2, Pp 674-687 (2014)
Sorting and degradation of receptors and associated signaling molecules maintain homeostasis of conserved signaling pathways during cell specification and tissue development. Yet, whether machineries that sort signaling proteins act preferentially on
Externí odkaz:
https://doaj.org/article/fac2dc6a120c4b5a81b814c1c6b66887
Autor:
Shiela C. Samson, Michelle C. Mendoza, Rediet Zewdu, Eric L. Snyder, Kelley Ingram, Rebecca G. Zitnay
Publikováno v:
Oncogene. 41:293-300
The RAS→RAF→MEK→ERK pathway is hyperactivated in the majority of human lung adenocarcinoma (LUAD). However, the initial activating mutations induce homeostatic feedback mechanisms that limit ERK activity. How ERK activation reaches the tumor-pr
Autor:
Kelley, Ingram, Shiela C, Samson, Rediet, Zewdu, Rebecca G, Zitnay, Eric L, Snyder, Michelle C, Mendoza
Publikováno v:
Oncogene. 41(2)
The RAS→RAF→MEK→ERK pathway is hyperactivated in the majority of human lung adenocarcinoma (LUAD). However, the initial activating mutations induce homeostatic feedback mechanisms that limit ERK activity. How ERK activation reaches the tumor-pr
Autor:
Alex Jones, Eric L. Snyder, Elnaz Mirzaei Mehrabad, Rediet Zewdu, Kelley Ingram, Pengshu Fang, Soledad A. Camolotto, Benjamin T Spike, Grace Orstad, Katherine L Gillis, Michelle C. Mendoza
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Cancer cells undergo lineage switching during natural progression and in response to therapy. NKX2-1 loss in human and murine lung adenocarcinoma leads to invasive mucinous adenocarcinoma (IMA), a lung cancer subtype that exhibits gastric differentia
Autor:
Rediet Zewdu, Pengshu Fang, Alex Jones, Soledad A. Camolotto, Elnaz Mirzaei Mehrabad, Eric L. Snyder, Michelle C. Mendoza, Katherine L Gillis, Benjamin T Spike, Kelley Ingram, Grace Orstad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f25c9a81294e5dc6de61feae747b645a
https://doi.org/10.7554/elife.66788.sa2
https://doi.org/10.7554/elife.66788.sa2
Autor:
Kelley Ingram, Eric L. Snyder, Benjamin T Spike, Alex Jones, Elnaz Mirzaei Mehrabad, Soledad A. Camolotto, Rediet Zewdu, Michelle C. Mendoza
Cancer cells often undergo lineage switching during their natural progression and in response to therapy. Lung adenocarcinomas (LUADs) exhibit a variety of differentiation states accompanied by dysregulation of lineage-specific transcription factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ec475f80e8eb67cc3274d9112ed76e2
Autor:
Maurizio Risolino, Licia Selleri, Alexandru Barbulescu, Jason M. Butler, Rediet Zewdu, Pradeep Ramalingam
Publikováno v:
Journal of anatomy, vol 229, iss 1
Zewdu, R; Risolino, M; Barbulescu, A; Ramalingam, P; Butler, JM; & Selleri, L. (2016). Spleen hypoplasia leads to abnormal stress hematopoiesis in mice with loss of Pbx homeoproteins in splenic mesenchyme. JOURNAL OF ANATOMY, 229(1), 153-169. doi: 10.1111/joa.12479. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/5735d04c
Zewdu, R; Risolino, M; Barbulescu, A; Ramalingam, P; Butler, JM; & Selleri, L. (2016). Spleen hypoplasia leads to abnormal stress hematopoiesis in mice with loss of Pbx homeoproteins in splenic mesenchyme. JOURNAL OF ANATOMY, 229(1), 153-169. doi: 10.1111/joa.12479. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/5735d04c
The spleen plays critical roles in immunity and also provides a permissive microenvironment for hematopoiesis. Previous studies have reported that the TALE-class homeodomain transcription factor Pbx1 is essential in hematopoietic stem and progenitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac642b78dc63287292561ef722f9f88d
https://escholarship.org/uc/item/5735d04c
https://escholarship.org/uc/item/5735d04c
Autor:
Julie Lacombe, Licia Selleri, David H. Lee, Heekyung Jung, Polyxeni Philippidou, Jeremy S. Dasen, Lisa Cohen, Olivia Hanley, Rediet Zewdu
Publikováno v:
Hanley, O; Zewdu, R; Cohen, LJ; Jung, H; Lacombe, J; Philippidou, P; et al.(2016). Parallel Pbx-Dependent Pathways Govern the Coalescence and Fate of Motor Columns. NEURON, 91(5), 1005-1020. doi: 10.1016/j.neuron.2016.07.043. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/7641z9d9
Neuron, vol 91, iss 5
Neuron, vol 91, iss 5
The clustering of neurons sharing similar functional properties and connectivity is a common organizational feature of vertebrate nervous systems. Within motor networks, spinal motor neurons (MNs) segregate into longitudinally arrayed subtypes, estab
Autor:
Michael J. Dixon, Trevor Williams, Licia Selleri, Matthew J. Anderson, Jill Dixon, Victoria Wells, Jean M. Hébert, Rediet Zewdu, Michael J. Depew, Bingsi Li, Courtney M. Karner, Elisabetta Ferretti
Publikováno v:
Developmental Cell. 21:627-641
Morphogenesis of mammalian facial processes requires coordination of cellular proliferation, migration, and apoptosis to develop intricate features. Cleft lip and/or palate (CL/P), the most frequent human craniofacial birth defect, can be caused by p