RGS4 promotes allergen- and aspirin-associated airway hyperresponsiveness by inhibiting PGE2 biosynthesis

Autor: Wong, Gordon S., Redes, Jamie L., Balenga, Nariman, McCullough, Morgan, Fuentes, Nathalie, Gokhale, Ameya, Koziol-White, Cynthia, Jude, Joseph A., Madigan, Laura A., Chan, Eunice C., Jester, William H., Biardel, Sabrina, Flamand, Nicolas, Panettieri, Reynold A., Jr., Druey, Kirk M.

Publikováno v: In The Journal of Allergy and Clinical Immunology November 2020 146(5):1152-1164

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Aspergillus fumigatus -Secreted Alkaline Protease 1 Mediates Airways Hyperresponsiveness in Severe Asthma.

Autor: Redes JL; Lung and Vascular Inflammation Section, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases/National Institutes of Health, Bethesda, MD 20892., Basu T; Lung and Vascular Inflammation Section, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases/National Institutes of Health, Bethesda, MD 20892., Ram-Mohan S; Center for Vascular Biology Research, Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215., Ghosh CC; Center for Vascular Biology Research, Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215., Chan EC; Lung and Vascular Inflammation Section, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases/National Institutes of Health, Bethesda, MD 20892., Sek AC; Inflammation Immunobiology Section, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases/National Institutes of Health, Bethesda, MD 20892; and., Zhao M; Protein Chemistry Section, Research Technologies Branch, National Institute of Allergy and Infectious Diseases/National Institutes of Health, Rockville, MD 20852., Krishnan R; Center for Vascular Biology Research, Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215., Rosenberg HF; Inflammation Immunobiology Section, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases/National Institutes of Health, Bethesda, MD 20892; and., Druey KM; Lung and Vascular Inflammation Section, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases/National Institutes of Health, Bethesda, MD 20892; kdruey@niaid.nih.gov.

Publikováno v: ImmunoHorizons [Immunohorizons] 2019 Aug 06; Vol. 3 (8), pp. 368-377. Date of Electronic Publication: 2019 Aug 06.