Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Reddy Kummetha"'
Autor:
Zhouting Zhu, Rachel Tang, Sarah Huff, Indrasena Reddy Kummetha, Lingling Wang, Na Li, Tariq M. Rana
Publikováno v:
Cancer Research Communications. 3:119-129
Although immune checkpoint inhibitors targeting T-cell immunoregulatory proteins have revolutionized cancer treatment, they are effective only in a limited number of patients, and new strategies are needed to enhance tumor responses to immunotherapie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::128ef508f418263e7f754d3a222d6b43
https://doi.org/10.1158/2767-9764.crc-21-0186
https://doi.org/10.1158/2767-9764.crc-21-0186
Autor:
Sarah Huff, Indrasena Reddy Kummetha, Lingzhi Zhang, Lingling Wang, William Bray, Jiekai Yin, Vanessa Kelley, Yinsheng Wang, Tariq M. Rana
Publikováno v:
Journal of Medicinal Chemistry. 65:10920-10937
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b65ae28ead01f4dfa90f4a467f8f52c
https://doi.org/10.1021/acs.jmedchem.1c02075
https://doi.org/10.1021/acs.jmedchem.1c02075
Autor:
Mark Sharkey, Natalia Sharova, Idrees Mohammed, Sarah E. Huff, Indrasena Reddy Kummetha, Gatikrushna Singh, Tariq M. Rana, Mario Stevenson
Publikováno v:
mBio, Vol 10, Iss 1 (2019)
ABSTRACT The HIV-1 accessory protein Vif, which counteracts the antiviral action of the DNA-editing cytidine deaminase APOBEC3G (A3G), is an attractive and yet unexploited therapeutic target. Vif reduces the virion incorporation of A3G by targeting t
Externí odkaz:
https://doaj.org/article/4d8741ca218e4772905c111bd892ffb2
Publikováno v:
In Polymer 28 September 2015 75:141-150
Autor:
Tariq M. Rana, Na Li, Lingling Wang, Indrasena Reddy Kummetha, Sarah Huff, Rachel Tang, Zhouting Zhu
Supplementary Figure S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7844afe936528d05e52ff4c0bed1713d
https://doi.org/10.1158/2767-9764.22546425
https://doi.org/10.1158/2767-9764.22546425
Autor:
Tariq M. Rana, Na Li, Lingling Wang, Indrasena Reddy Kummetha, Sarah Huff, Rachel Tang, Zhouting Zhu
Although immune checkpoint inhibitors targeting T-cell immunoregulatory proteins have revolutionized cancer treatment, they are effective only in a limited number of patients, and new strategies are needed to enhance tumor responses to immunotherapie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd182e0332b515481febdc3177d6137
https://doi.org/10.1158/2767-9764.c.6551172.v1
https://doi.org/10.1158/2767-9764.c.6551172.v1
Autor:
Tariq M. Rana, Na Li, Lingling Wang, Indrasena Reddy Kummetha, Sarah Huff, Rachel Tang, Zhouting Zhu
Compounds design, synthesis, and characterization Table S1. Calculated physicochemical properties of Ptpn2 inhibitors.Table S2. CRISPR target guide sequence to generate stable cell lines.Table S3. The primers used for quantitative RT-PCR.Figures S1 -
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::894fdd030afb4719a65600e3af69d98f
https://doi.org/10.1158/2767-9764.22546416
https://doi.org/10.1158/2767-9764.22546416
Autor:
Tariq M. Rana, Yunlin Zhang, Rachel Tang, Gianluigi Lichinchi, Indrasena Reddy Kummetha, Edwin H. Yau
Table with gene level analysis of transduction replicates in the secondary sgRNA library screen using STARS score
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38467a9000b6eabd94a251c08ef01548
https://doi.org/10.1158/0008-5472.22414110.v1
https://doi.org/10.1158/0008-5472.22414110.v1
Autor:
Tariq M. Rana, Yunlin Zhang, Rachel Tang, Gianluigi Lichinchi, Indrasena Reddy Kummetha, Edwin H. Yau
This file contains supplemental figures S1-S4. Figure S1 - library abundance and replicate correlation of genome-wide CRISPR screen. Figure S2 - Validation experiments for candidate metabolic synthetic lethal candidates. Figure S3 - Venn diagram for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5c48626082ce2f290f30f92fcd6d733
https://doi.org/10.1158/0008-5472.22414125.v1
https://doi.org/10.1158/0008-5472.22414125.v1
Autor:
Tariq M. Rana, Yunlin Zhang, Rachel Tang, Gianluigi Lichinchi, Indrasena Reddy Kummetha, Edwin H. Yau
Targeting mutant KRAS signaling pathways continues to attract attention as a therapeutic strategy for KRAS-driven tumors. In this study, we exploited the power of the CRISPR-Cas9 system to identify genes affecting the tumor xenograft growth of human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::091d2b2645bbc353179e708581955623
https://doi.org/10.1158/0008-5472.c.6508893
https://doi.org/10.1158/0008-5472.c.6508893