Structural insertion/deletion variation in IRF5 is associated with a risk haplotype and defines the precise IRF5 isoforms expressed in systemic lupus erythematosus

Autor: Kozyrev, Sergey V, Lewén, Susanna, Reddy, Prasad M V Linga, Pons-Estel, Bernardo, Collaborative Group, Argentine, Witte, Torsten, Collaborative Group, German, Junker, Peter, Laustrup, Helle, Gutiérrez, Carmen, Suárez, Ana, Francisca González-Escribano, Maria, Martín, Javier, Collaborative Group, Spanish, Alarcón-Riquelme, Marta E

Publikováno v: Kozyrev, S V, Lewén, S, Reddy, P M V L, Pons-Estel, B, Collaborative Group, A, Witte, T, Collaborative Group, G, Junker, P, Laustrup, H, Gutiérrez, C, Suárez, A, Francisca González-Escribano, M, Martín, J, Collaborative Group, S & Alarcón-Riquelme, M E 2007, ' Structural insertion/deletion variation in IRF5 is associated with a risk haplotype and defines the precise IRF5 isoforms expressed in systemic lupus erythematosus ', Arthritis & Rheumatism, vol. 56, no. 4, pp. 1234-41 . https://doi.org/10.1002/art.22497

Objective To determine whether specific isoforms of IRF5 are transcribed in patients with systemic lupus erythematosus (SLE) who have risk genotypes in the exon 1B donor splice site at single-nucleotide polymorphism (SNP) no. rs2004640. Methods Perip

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https://doi.org/10.1002/art.22497

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