Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Redding Gober"'
Autor:
Alessio Terenzi, Mery La Franca, Sushilla van Schoonhoven, Rostyslav Panchuk, Álvaro Martínez, Petra Heffeter, Redding Gober, Christine Pirker, Petra Vician, Christian R. Kowol, Rostyslav Stoika, Luca Salassa, Jürgen Rohr, Walter Berger
Publikováno v:
Communications Chemistry, Vol 4, Iss 1, Pp 1-13 (2021)
Landomycins are promising anti-cancer agents with the potential to bypass common resistance pathways, but their mechanism of action remains incompletely understood. Here a mechanism is proposed involving intracellular sequential thiol-Michael and oxi
Externí odkaz:
https://doaj.org/article/bdb5050705c84bce940244077ea65781
Autor:
Christine Pirker, Jürgen Rohr, Alessio Terenzi, Sushilla van Schoonhoven, Petra Vician, Christian R. Kowol, Luca Salassa, Rostyslav Stoika, Petra Heffeter, Álvaro Martínez, R. R. Panchuk, Walter Berger, Redding Gober, Mery La Franca
Publikováno v:
Communications Chemistry, Vol 4, Iss 1, Pp 1-13 (2021)
Landomycins are angucyclines with promising antineoplastic activity produced by Streptomyces bacteria. The aglycone landomycinone is the distinctive core, while the oligosaccharide chain differs within derivatives. Herein, we report that landomycins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5b11d8f08a4c0aedc42e766d0802d59
https://doi.org/10.1038/s42004-021-00600-4
https://doi.org/10.1038/s42004-021-00600-4
Publikováno v:
MedChemComm. 10:1855-1866
Natural products are produced by bacteria, plants, and fungi and have yielded some of the most clinically active and widely used drugs available. Several of the natural products that are produced by type II PKSs have novel scaffolds or unique rearran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76449380dc9a4964cd25f2f64caea044
https://doi.org/10.1039/c9md00066f
https://doi.org/10.1039/c9md00066f