Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Reda Z. Mahfouz"'
Autor:
Yogen Saunthararajah, Tomas Radivoyevitch, Jaroslaw Maciejewski, Ramon Tiu, Mikkael A. Sekeres, Kory J. Engelke, Yonghua Ling, Kenneth Chan, Joseph Covey, Pramod Terse, Ali Tabarroki, Valeria Visconte, Xiaorong Gu, Quteba Ebrahem, Ania Jankowska, Reda Z. Mahfouz
Purpose: The cytidine analogs 5-azacytidine and decitabine, used to treat myelodysplastic syndromes (MDS), produce a molecular epigenetic effect, depletion of DNA-methyltransferase 1 (DNMT1). This action is S-phase dependent. Hence, genetic factors t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::373c9f8453963162b9091ebec5310cce
https://doi.org/10.1158/1078-0432.c.6521568
https://doi.org/10.1158/1078-0432.c.6521568
Autor:
Yogen Saunthararajah, Tomas Radivoyevitch, Jaroslaw Maciejewski, Ramon Tiu, Mikkael A. Sekeres, Kory J. Engelke, Yonghua Ling, Kenneth Chan, Joseph Covey, Pramod Terse, Ali Tabarroki, Valeria Visconte, Xiaorong Gu, Quteba Ebrahem, Ania Jankowska, Reda Z. Mahfouz
PDF file - 297K, Figure S1: CDA mRNA expression in various human tissues. Figure S2: CDA mRNA expression in primary cancer cells. Figure S3: Incidence of MDS in the United States.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69ec346f909f91c8916a876860d6b3b3
https://doi.org/10.1158/1078-0432.22449147
https://doi.org/10.1158/1078-0432.22449147
Autor:
Alan E. Lichtin, Hetty E. Carraway, Ashwin Kishtagari, Yogen Saunthararajah, Jibran Durrani, Tomas Radivoyevitch, Cassandra M Kerr, Bhumika J. Patel, Valeria Visconte, Hassan Awada, Reda Z. Mahfouz, Teodora Kuzmanovic, Jaroslaw P. Maciejewski
Publikováno v:
British Journal of Haematology
Summary The nucleoside analogue decitabine can deplete the epigenetic regulator DNA methyltransferase 1 (DNMT1), an effect that occurs, and is saturated at, low concentrations/doses. A reason to pursue this molecular‐targeted effect instead of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::831868f1b18d727ce07ba7d9a4b51e42
https://doi.org/10.1111/bjh.16281
https://doi.org/10.1111/bjh.16281
Autor:
Robert M. Dean, Ehsan Malek, Hien Liu, Janice Reed, Wei Wei, Erica L. Campagnaro, Beth Faiman, Sherry Fada, Jason Valent, Kimberly Hamilton, Ronald Sobecks, Babal K. Jha, Matt Kalaycio, Jack Khouri, Mohammed S. Orloff, Reda Z. Mahfouz, Mary Ann Karam, Yap Chew, Christy J. Samaras, Frederic J. Reu, Yogen Saunthararajah, Dale Grabowski, Hillard M. Lazarus, Shahper N. Khan
Publikováno v:
Seminars in hematology. 58(1)
The DNA methyltransferase inhibitor azacytidine (aza) may reactivate pathways associated with plasma cell differentiation, cell cycle control, apoptosis, and immune recognition and thereby restore sensitivity to lenalidomide (len) and dexamethasone (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0097460cfa780566ba330078be35a0f
https://pubmed.ncbi.nlm.nih.gov/33509443
https://pubmed.ncbi.nlm.nih.gov/33509443
Autor:
Samar Salman, Azza G. A. Farag, Nada Farag Elnaidany, Reda Z. Mahfouz, Mona Salah El‑din Habib, Ashraf Anas Zytoon, Reda A Ibrahem
Publikováno v:
Journal of the Egyptian Womenʼs Dermatologic Society. 15:80-87
BackgroundMean platelet volume (MPV), may help to determine atherosclerosis threat. Cardiovascular disease is one of the common causes of morbidity and mortality in patients having psoriasis.ObjectiveTo examine MPV as a biomarker for subclinical athe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee0ff4da6ba3e4495a033d4ddd3e67ae
https://doi.org/10.1097/01.ewx.0000532719.31339.7c
https://doi.org/10.1097/01.ewx.0000532719.31339.7c
Autor:
Mostafa A Hammam, Reda Z. Mahfouz, Azza G. A. Farag, Nada Farag Elnaidany, Masroor Qutubuddin, Reda A Ibrahem, Rehab R. E. Tolba
Publikováno v:
Mycoses. 61:321-325
Most superficial mycotic infections of human skin are due to dermatophytes. Children are frequently affected due to different predisposing factors, particularly overcrowding in classrooms. This study aimed to estimate the prevalence of dermatophytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b198bbf2260b240ec6edbafc0995db80
https://doi.org/10.1111/myc.12743
https://doi.org/10.1111/myc.12743
Autor:
Nashwa M. Muharram, Nada Farag Elnaidany, Magda M Haggag, Reda Z. Mahfouz, Azza G. A. Farag, Hoda M. Abd El Ghany
Publikováno v:
Journal of the Egyptian Womenʼs Dermatologic Society. 15:30-34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7902426adf834748a1b5d76b7beb939f
https://doi.org/10.1097/01.ewx.0000525983.54753.6
https://doi.org/10.1097/01.ewx.0000525983.54753.6
Autor:
Yasunobu Nagata, Teodora Kuzmanovic, Seishi Ogawa, Bartlomiej P Przychodzen, Tetsuichi Yoshizato, Reda Z. Mahfouz, Eiju Negoro, Aziz Nazha, Michael J. Clemente, Wenyi Shen, Jaroslaw P. Maciejewski, Cassandra M. Hirsch, Hideki Makishima, Naoko Hosono, Mikkael A. Sekeres
Publikováno v:
Blood. 130:1953-1957
To the editor: The course of aplastic anemia (AA) is often complicated by the development of clonal disorders such as paroxysmal nocturnal hemoglobinuria (PNH) and secondary myelodysplastic syndromes (sMDS).[1][1][⇓][2][⇓][3][⇓][4]-[5][5] Ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecf67eae8dbec3dd7e5d7b7018cf0abe
https://doi.org/10.1182/blood-2017-02-767731
https://doi.org/10.1182/blood-2017-02-767731
Publikováno v:
The Korean Journal of Pain
Background Postoperative pain is a common, distressing symptom following arthroscopic knee surgery. The aim of this study was to compare the potential analgesic effect of dexmedetomidine after intrathecal versus intra-articular administration followi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1289105d04f6a50ef2b675651fdf69a
http://europepmc.org/articles/PMC5392657
http://europepmc.org/articles/PMC5392657
Autor:
Betty K. Hamilton, Valeria Visconte, Hetty E. Carraway, Navneet S. Majhail, Alan E. Lichtin, Jaroslaw P. Maciejewski, Matt Kalaycio, Aziz Nazha, Jibran Durrani, Ashwin Kishtagari, Hassan Awada, Mikkael A. Sekeres, Brian T. Hill, Deepa Jagadeesh, Reda Z. Mahfouz, Ronald Sobecks
Publikováno v:
Br J Haematol
T-cell large granular lymphocyte leukaemia (T-LGLL) is a chronic clonal lymphoproliferative disorder of cytotoxic T lymphocytes (CTL), which commonly occurs in older patients and is often associated with autoimmune diseases. Among 246 patients with T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02fa7b2f4ae9ae39f829332564c72c4d
https://pubmed.ncbi.nlm.nih.gov/31958160
https://pubmed.ncbi.nlm.nih.gov/31958160