Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Reda Stankunaite"'
Autor:
Mareike Berlak, Elizabeth Tucker, Mathurin Dorel, Annika Winkler, Aleixandria McGearey, Elias Rodriguez-Fos, Barbara Martins da Costa, Karen Barker, Elicia Fyle, Elizabeth Calton, Selma Eising, Kim Ober, Deborah Hughes, Eleni Koutroumanidou, Paul Carter, Reda Stankunaite, Paula Proszek, Neha Jain, Carolina Rosswog, Heathcliff Dorado-Garcia, Jan Jasper Molenaar, Mike Hubank, Giuseppe Barone, John Anderson, Peter Lang, Hedwig Elisabeth Deubzer, Annette Künkele, Matthias Fischer, Angelika Eggert, Charlotte Kloft, Anton George Henssen, Michael Boettcher, Falk Hertwig, Nils Blüthgen, Louis Chesler, Johannes Hubertus Schulte
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-19 (2022)
Abstract Background Development of resistance to targeted therapies has tempered initial optimism that precision oncology would improve poor outcomes for cancer patients. Resistance mechanisms, however, can also confer new resistance-specific vulnera
Externí odkaz:
https://doaj.org/article/141d19867f1b4f5b98e903127aa48cab
Autor:
Reda Stankunaite, Lynley V. Marshall, Fernando Carceller, Louis Chesler, Michael Hubank, Sally L. George
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
Circulating cell-free DNA (cfDNA) analysis has the potential to revolutionise the care of patients with cancer and is already moving towards standard of care in some adult malignancies. Evidence for the utility of cfDNA analysis in paediatric cancer
Externí odkaz:
https://doaj.org/article/08dbef97b1da4600a388a638049530a0
Autor:
Chris Jones, Fernando Carceller, Angel M. Carcaboso, Sabine Mueller, Andres Morales La Madrid, Ofelia Cruz, Michael Hubank, Jacques Grill, Jeremy Pryce, Ashirwad Merve, Safa Al-Sarraj, Bassel Zebian, Andrew Mackinnon, David Sheppard, Anne Phelan, John P. Overington, Alan Mackay, Sara Temelso, Florence I. Raynaud, Akos Pal, Adam Donovan, Ruth Ruddle, Daniel P. Smith, Elizabeth A. Corley, Valeria Molinari, Cinzia Lavarino, Reda Stankunaite, Nagore Olaciregui, Peter J. Richardson, Diana M. Carvalho
Somatic mutations in ACVR1 are found in a quarter of children with diffuse intrinsic pontine glioma (DIPG), but there are no ACVR1 inhibitors licensed for the disease. Using an artificial intelligence–based platform to search for approved compounds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccde98c1d976dc080bc75d98bfc49331
https://doi.org/10.1158/2159-8290.c.6549445
https://doi.org/10.1158/2159-8290.c.6549445
Autor:
Chris Jones, Fernando Carceller, Angel M. Carcaboso, Sabine Mueller, Andres Morales La Madrid, Ofelia Cruz, Michael Hubank, Jacques Grill, Jeremy Pryce, Ashirwad Merve, Safa Al-Sarraj, Bassel Zebian, Andrew Mackinnon, David Sheppard, Anne Phelan, John P. Overington, Alan Mackay, Sara Temelso, Florence I. Raynaud, Akos Pal, Adam Donovan, Ruth Ruddle, Daniel P. Smith, Elizabeth A. Corley, Valeria Molinari, Cinzia Lavarino, Reda Stankunaite, Nagore Olaciregui, Peter J. Richardson, Diana M. Carvalho
Supplementary Figures S1-S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0da7c8cb2db6fbcf863e79ec10b5d492
https://doi.org/10.1158/2159-8290.22540657.v1
https://doi.org/10.1158/2159-8290.22540657.v1
Autor:
Reda Stankunaite, Sally L. George, Lewis Gallagher, Sabri Jamal, Ridwan Shaikh, Lina Yuan, Debbie Hughes, Paula Z. Proszek, Paul Carter, Grzegorz Pietka, Timon Heide, Chela James, Haider Tari, Claire Lynn, Neha Jain, Laura Rey Portela, Tony Rogers, Sucheta J. Vaidya, Julia C. Chisholm, Fernando Carceller, Elwira Szychot, Henry Mandeville, Paola Angelini, Angela B. Jesudason, Michael Jackson, Lynley V. Marshall, Susanne A. Gatz, John Anderson, Andrea Sottoriva, Louis Chesler, Michael Hubank
Publikováno v:
European Journal of Cancer. 162:209-220
Clinical diagnostic sequencing of circulating tumour DNA (ctDNA) is well advanced for adult patients, but application to paediatric cancer patients lags behind.To address this, we have developed a clinically relevant (67 gene) NGS capture panel and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edcedb32be66e248bdc667dcd2ff184f
https://doi.org/10.1016/j.ejca.2021.09.042
https://doi.org/10.1016/j.ejca.2021.09.042
Autor:
Andrew D MacKinnon, Sabine Mueller, Sara Temelso, Ashirwad Merve, Alan Mackay, Reda Stankunaite, Chris Jones, Daniel P. Smith, Safa Al-Sarraj, Andres Morales La Madrid, Jacques Grill, Adam Donovan, Ofelia Cruz, Mike Hubank, David Sheppard, Cinzia Lavarino, Anne Phelan, Bassel Zebian, Valeria Molinari, Angel M. Carcaboso, Diana Carvalho, Jeremy Pryce, Elizabeth A Corley, Fernando Carceller, Ruth Ruddle, Nagore G. Olaciregui, Akos Pal, Florence I. Raynaud, Peter John Richardson, John P. Overington
Publikováno v:
Cancer Discovery. 12:416-431
Somatic mutations in ACVR1 are found in a quarter of children with diffuse intrinsic pontine glioma (DIPG), but there are no ACVR1 inhibitors licensed for the disease. Using an artificial intelligence–based platform to search for approved compounds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b574b0286a4c7dd08580121bfee58ccb
https://doi.org/10.1158/2159-8290.cd-20-1201
https://doi.org/10.1158/2159-8290.cd-20-1201
Autor:
Olivia Ruhen, Nathalie S.M. Lak, Janine Stutterheim, Sara G. Danielli, Mathieu Chicard, Yasmine Iddir, Alexandra Saint-Charles, Virginia Di Paolo, Lucia Tombolan, Susanne A. Gatz, Ewa Aladowicz, Paula Proszek, Sabri Jamal, Reda Stankunaite, Deborah Hughes, Paul Carter, Elisa Izquierdo, Ajla Wasti, Julia C. Chisholm, Sally L. George, Erika Pace, Louis Chesler, Isabelle Aerts, Gaelle Pierron, Sakina Zaidi, Olivier Delattre, Didier Surdez, Anna Kelsey, Michael Hubank, Paolo Bonvini, Gianni Bisogno, Angela Di Giannatale, Gudrun Schleiermacher, Beat W. Schäfer, Godelieve A.M. Tytgat, Janet Shipley
Publikováno v:
JCO precision oncology. 6
PURPOSE Rhabdomyosarcomas (RMS) are rare neoplasms affecting children and young adults. Efforts to improve patient survival have been undermined by a lack of suitable disease markers. Plasma circulating tumor DNA (ctDNA) has shown promise as a potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd26439d745faab9a7b2f16a3932ebe6
https://pubmed.ncbi.nlm.nih.gov/36265118
https://pubmed.ncbi.nlm.nih.gov/36265118
Autor:
Andrew D MacKinnon, Chris Jones, Andres Morales La Madrid, Ofelia Cruz, Peter D. Richardson, Nagore G. Olaciregui, Akos Pal, Cinzia Lavarino, Sabine Mueller, Valeria Molinari, Diana Carvalho, Adam Donovan, Reda Stankunaite, Angel M. Carcaboso, Elizabeth A Corley, Dave Sheppard, Fernando Carceller, Ruth Ruddle, Mike Hubank, Florence I. Raynaud, Anne Phelan, John P. Overington
Publikováno v:
Neuro Oncol
Somatic mutations in ACVR1, encoding the serine/threonine kinase ALK2 receptor, are found in a quarter of children with the currently incurable brain tumour diffuse intrinsic pontine glioma (DIPG). Treatment of ACVR1-mutant DIPG patient-derived model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dea45ea8644cb06fc78c43952a093d8c
https://europepmc.org/articles/PMC7651129/
https://europepmc.org/articles/PMC7651129/
Autor:
Diana M, Carvalho, Peter J, Richardson, Nagore, Olaciregui, Reda, Stankunaite, Cinzia, Lavarino, Valeria, Molinari, Elizabeth A, Corley, Daniel P, Smith, Ruth, Ruddle, Adam, Donovan, Akos, Pal, Florence I, Raynaud, Sara, Temelso, Alan, Mackay, John P, Overington, Anne, Phelan, David, Sheppard, Andrew, Mackinnon, Bassel, Zebian, Safa, Al-Sarraj, Ashirwad, Merve, Jeremy, Pryce, Jacques, Grill, Michael, Hubank, Ofelia, Cruz, Andres, Morales La Madrid, Sabine, Mueller, Angel M, Carcaboso, Fernando, Carceller, Chris, Jones
Publikováno v:
Cancer Discov
Somatic mutations in ACVR1 are found in a quarter of children with diffuse intrinsic pontine glioma (DIPG), however there are no ACVR1 inhibitors licensed for the disease. Using an Artificial Intelligence-based platform to search for approved compoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::780cd6e4583edd20db881decc75f7ed7
https://pubmed.ncbi.nlm.nih.gov/34551970
https://pubmed.ncbi.nlm.nih.gov/34551970