Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Reda R. Mabrouk"'
Autor:
Abdallah E. Abdallah, Reda R. Mabrouk, Maged Mohammed Saleh Al Ward, Sally I. Eissa, Eslam B. Elkaeed, Ahmed B. M. Mehany, Mariam A. Abo-Saif, Ola A. El-Feky, Mohamed S. Alesawy, Mohamed Ayman El-Zahabi
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 573-591 (2022)
Based on quinazoline, quinoxaline, and nitrobenzene scaffolds and on pharmacophoric features of VEGFR-2 inhibitors, 17 novel compounds were designed and synthesised. VEGFR-2 IC50 values ranged from 60.00 to 123.85 nM for the new derivatives compared
Externí odkaz:
https://doaj.org/article/3af1c5c676984e4bb4c5c70fd837b96c
Autor:
Abdallah E Abdallah, Reda R Mabrouk, Mohamed R Elnagar, Amel Mostafa Farrag, Mohamed H Kalaba, Mohamed H Sharaf, Esmail M El-Fakharany, Dina Abed Bakhotmah, Eslam B Elkaeed, Maged Mohammed Saleh Al Ward
Publikováno v:
Drug Design, Development and Therapy.
Abdallah E Abdallah,1 Reda R Mabrouk,1 Mohamed R Elnagar,2 Amel Mostafa Farrag,3 Mohamed H Kalaba,4 Mohamed H Sharaf,4 Esmail M El-Fakharany,5 Dina Abed Bakhotmah,6 Eslam B Elkaeed,7 Maged Mohammed Saleh Al Ward1 1Pharmaceutical Medicinal Chemistry &
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d67b6d8c630ffc7a33cb08f710453e17
https://www.dovepress.com/new-series-of-vegfr-2-inhibitors-and-apoptosis-enhancers-design-synthe-peer-reviewed-fulltext-article-DDDT
https://www.dovepress.com/new-series-of-vegfr-2-inhibitors-and-apoptosis-enhancers-design-synthe-peer-reviewed-fulltext-article-DDDT
Autor:
Maged Mohammed Saleh Al Ward, Ahmed B.M. Mehany, Mohamed El-Zahabi, Reda R. Mabrouk, Abdallah E. Abdallah, Sally I. Eissa
Publikováno v:
Bioorganic Chemistry. 109:104695
Globally cancer is the second leading cause of death. So that this work is an attempt to develop new effective anti-cancer agents. In line with pharmacophoric features of VEGFR-2 kinase inhibitors, new nineteen quinazolin-4-one derivatives were desig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15955ffd888a215ded4f3666ee62a37b
https://doi.org/10.1016/j.bioorg.2021.104695
https://doi.org/10.1016/j.bioorg.2021.104695