Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Reda Mhidia"'
Autor:
Rémi Desmet, Céline Boidin‐Wichlacz, Reda Mhidia, Aurélie Tasiemski, Vangelis Agouridas, Oleg Melnyk
Publikováno v:
Angewandte Chemie International Edition
Angewandte Chemie International Edition, 2023, ⟨10.1002/anie.202302648⟩
Angewandte Chemie International Edition, 2023, ⟨10.1002/anie.202302648⟩
Autor:
Emmanuelle Boll, Oleg Melnyk, Nathalie Ollivier, Hervé Drobecq, Julien Dheur, Laurent Raibaut, Rémi Desmet, Reda Mhidia, Annick Blanpain, Silvain L. Pira
Publikováno v:
Journal of Peptide Science. 20:92-97
Protein total chemical synthesis enables the atom-by-atom control of the protein structure and therefore has a great potential for studying protein function. Native chemical ligation of C-terminal peptide thioesters with N-terminal cysteinyl peptides
Exploration of an imide capture/N,N-acyl shift sequence for asparagine native peptide bond formation
Autor:
Reda Mhidia, Nathalie Ollivier, David Crich, Bernard Delpech, Mikhail S. Ermolenko, Oleg Melnyk, Kaname Sasaki, Emmanuelle Boll, Fabien Fécourt
Publikováno v:
Bioorganic and Medicinal Chemistry
Bioorganic and Medicinal Chemistry, Elsevier, 2013, 21 (12), pp.3479-85. ⟨10.1016/j.bmc.2013.02.053⟩
Bioorganic and Medicinal Chemistry, Elsevier, 2013, 21 (12), pp.3479-85. ⟨10.1016/j.bmc.2013.02.053⟩
International audience; Imide capture of a C-terminal peptidylazide with a side-chain thioacid derivative of an N-terminally protected aspartyl peptide leads to the formation of an imide bond bringing the two peptide ends into close proximity. Unmask
Autor:
Reda Mhidia, Oleg Melnyk, Ludger Johannes, Romain Christiano, Annick Blanpain, Getao Shi, Nathalie Ollivier, Aurélie Vallin
Publikováno v:
Bioconjugate Chemistry. 21:219-228
Peptide-protein conjugates are useful tools in different fields of research as, for instance, the development of vaccines and drugs or for studying biological mechanisms, to cite only few applications. N-Succinimidyl carbamate (NSC) chemistry has bee
Autor:
Reda Mhidia, Julien Dheur, Annick Blanpain, Silvain L. Pira, Hervé Drobecq, Emmanuelle Boll, Oleg Melnyk, Laurent Raibaut, Nathalie Ollivier, Rémi Desmet
Publikováno v:
ChemInform. 45
Protein total chemical synthesis enables the atom-by-atom control of the protein structure and therefore has a great potential for studying protein function. Native chemical ligation of C-terminal peptide thioesters with N-terminal cysteinyl peptides
Autor:
Nathalie, Ollivier, Laurent, Raibaut, Annick, Blanpain, Rémi, Desmet, Julien, Dheur, Reda, Mhidia, Emmanuelle, Boll, Hervé, Drobecq, Silvain L, Pira, Oleg, Melnyk
Publikováno v:
Journal of peptide science : an official publication of the European Peptide Society. 20(2)
Protein total chemical synthesis enables the atom-by-atom control of the protein structure and therefore has a great potential for studying protein function. Native chemical ligation of C-terminal peptide thioesters with N-terminal cysteinyl peptides
Publikováno v:
Organic letters. 12(22)
The reaction of a peptide featuring a bis(2-sulfanylethyl)amino (SEA) group on its C-terminus with a cysteinyl peptide in water at pH 7 and 37 °C leads to the chemoselective and regioselective formation of a native peptide bond. This method called S
Autor:
Reda Mhidia, Oleg Melnyk
Publikováno v:
Journal of Peptide Science.
Several reports have highlighted the interest of replacing Gly, a frequent amino acid within bioactive peptides, by azaGly (Agly) to improve their stability, activity or for the design of prodrugs. Because metal catalysis is increasingly used for tai
Publikováno v:
Organic Letters; Nov2010, Vol. 12 Issue 22, p5238-5241, 4p