Zobrazeno 1 - 10
of 327
pro vyhledávání: '"Recombinant inbred mice"'
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionFetal alcohol spectrum disorders (FASD) are the leading preventable cause of intellectual disability, providing the impetus for evaluating various potential treatments to ameliorate ethanol’s teratogenic effects, particularly in the ner
Externí odkaz:
https://doaj.org/article/f5e441aec0c241cf8b10845aa4d4695e
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 11, Pp 2452-2458 (2022)
[INLINE:1] Alzheimer’s disease (AD) is affected by genetic factors. Polymorphisms in the glutathione S-transferase omega-1 (Gsto1) gene have been shown by genetic correlation analyses performed in different ethnic populations to be genetic risk fac
Externí odkaz:
https://doaj.org/article/6357f5f289944e5da48c4eedf90d83a9
Autor:
Dassine Berdous, Xavier Berney, Ana Rodriguez Sanchez-Archidona, Maxime Jan, Clara Roujeau, Isabel C. Lopez-Mejia, Randall Mynatt, Bernard Thorens
Publikováno v:
Molecular Metabolism, Vol 37, Iss , Pp 100993- (2020)
Objectives: Glucose-stimulated insulin secretion is a critical function in the regulation of glucose homeostasis, and its deregulation is associated with the development of type 2 diabetes. Here, we performed a genetic screen using islets isolated fr
Externí odkaz:
https://doaj.org/article/9103d987d7864a2aba8fec731d2d5688
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
David George Ashbrook, Anna eDelprato, Claudia eGrellmann, Mareike eKlein, Richard eWetzel, Rupert W Overall, Alexandra eBadea
Publikováno v:
Frontiers in Neuroscience, Vol 8 (2014)
Adult neurogenesis, the lifelong production of new neurons in the adult brain, is under complex genetic control but many of the genes involved remain to be identified. In this study, we have integrated publicly available gene expression data from the
Externí odkaz:
https://doaj.org/article/c33f2c885bfc4fb0b6e20cbd2f04e9a9
Autor:
Maxime Jan, Dassine Berdous, Randall L. Mynatt, Ana Rodriguez Sanchez-Archidona, Isabel C. Lopez-Mejia, Xavier Berney, Clara Roujeau, Bernard Thorens
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 37, Iss, Pp 100993-(2020)
Molecular Metabolism, Vol 37, Iss, Pp 100993-(2020)
Objectives Glucose-stimulated insulin secretion is a critical function in the regulation of glucose homeostasis, and its deregulation is associated with the development of type 2 diabetes. Here, we performed a genetic screen using islets isolated fro
Autor:
Rupert W Overall, Gerd Kempermann, Jeremy Peirce, Lu Lu, Dan Goldowitz, Fred H Gage, Shirlean Goodwin, August B Smit, David C Airey, Glenn D Rosen, Leonard C Schalkwyk, Thomas R Sutter, Richard S. Nowakowski, Stephen Whatley, Robert W Williams
Publikováno v:
Frontiers in Neuroscience, Vol 3 (2009)
Differences in gene expression in the CNS influence behavior and disease susceptibility. To systematically explore the role of normal variation in expression on hippocampal structure and function, we generated an online microarray database for a dive
Externí odkaz:
https://doaj.org/article/63fcd0ddcbaa412dbdaba773d2c7d34f
Autor:
Monika M. Kaczmarek, Agnieszka Korytko, Agnieszka Chabowska-Kita, Anna Trabczynska, Leslie P. Kozak
Publikováno v:
The FASEB Journal
The brown adipocyte phenotype (BAP) in white adipose tissue (WAT) is transiently induced in adult mammals in response to reduced ambient temperature. Since it is unknown whether a cold challenge can permanently induce brown adipocytes (BAs), we reare