Zobrazeno 1 - 10
of 180
pro vyhledávání: '"Recombinant human soluble thrombomodulin"'
Autor:
Nobuyasu Awano, Taisuke Jo, Takehiro Izumo, Minoru Inomata, Kojiro Morita, Hiroki Matsui, Kiyohide Fushimi, Hirokazu Urushiyama, Takahide Nagase, Hideo Yasunaga
Publikováno v:
Journal of Intensive Care, Vol 10, Iss 1, Pp 1-9 (2022)
Abstract Background Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) is the leading cause of death among patients with IPF. However, there is no established treatment for this condition. Hence, we aimed to investigate the effectiveness an
Externí odkaz:
https://doaj.org/article/d6392ae8673e438b9503b037edac8c6a
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 6, Iss 1, Pp 1-5 (2020)
Abstract Background Although recombinant human soluble thrombomodulin (rTM) has been widely used to treat disseminated intravascular coagulation (DIC) in Japan, there is no consensus regarding rTM efficacy. Therefore, if the factors influencing rTM e
Externí odkaz:
https://doaj.org/article/7f73d5da3e6444148af9ccaa26f26ba8
Publikováno v:
Journal of Intensive Care, Vol 8, Iss 1, Pp 1-7 (2020)
Abstract Background Clinical evidence showing the effectiveness of recombinant human soluble thrombomodulin (rhTM) for treating sepsis-induced disseminated intravascular coagulation (DIC) and organ dysfunction (particularly renal injury) is limited b
Externí odkaz:
https://doaj.org/article/acfb3ed921f847d6adf6ae07fdbde523
Autor:
Hiroyuki Kamiya, Ogee Mer Panlaqui
Publikováno v:
BMC Pulmonary Medicine, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background Acute exacerbation (AE) of idiopathic pulmonary fibrosis (IPF) is devastating with no established treatment. This phenomenon involves disordered coagulation and excessive inflammatory reactions. As recombinant human soluble thromb
Externí odkaz:
https://doaj.org/article/7ef1122ec8224f34be038b0d5f96cb42
Akademický článek
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Autor:
Noriko Nakajima, Tran Minh Dien, Naoyuki Hirata, Shoji Kawachi, Akira Ainai, Jin Takasaki, Phuc Huu Phan, Thuy Thi Bich Phung, Dong Tien Ngo, Hiroyuki Nunoi, Tuan Anh Ta
Publikováno v:
Journal of Anesthesia
Purpose Recombinant human soluble thrombomodulin (rTM) has been used to treat disseminated intravascular coagulation (DIC). Recent studies have shown the efficacy of rTM through its anti-inflammatory effects for treatment of adults with acute respira
Akademický článek
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Autor:
Marcel Levi, David Fineberg, Toshihiko Kayanoki, Debra Hoppensteadt, Amanda H Radford, Jean Louis Vincent, Kosuke Tanaka, Jawed Fareed
Publikováno v:
Critical Care Medicine
Objectives To assess the effects of recombinant human soluble thrombomodulin treatment on 28-day all-cause mortality in subgroups categorized by baseline coagulation biomarker levels (prothrombin fragment 1.2, thrombin-antithrombin complex, D-dimer)
Akademický článek
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Publikováno v:
Clinical and Applied Thrombosis/Hemostasis, Vol 27 (2021)
Clinical and Applied Thrombosis/Hemostasis
Clinical and Applied Thrombosis/Hemostasis
To evaluate associations among coagulation-related variables, resolution of disseminated intravascular coagulation (DIC) and mortality, we retrospectively investigated 123 patients with sepsis-induced DIC treated with recombinant human soluble thromb