Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Reckzeh ES"'
Autor:
Ceballos, J, Schwalfenberg, M, Karageorgis, G, Reckzeh, ES, Sievers, S, Ostermann, C, Pahl, A, Sellstedt, M, Nowacki, J, Carnero Corrales, MA, Wilke, J, Laraia, L, Tschapalda, K, Metz, M, Sehr, DA, Brand, S, Winklhofer, K, Janning, P, Ziegler, S, Waldmann, H
Bioactive compound design based on natural product (NP) structure may be limited due to partial coverage of NP‐like chemical space and biological target space. These limitations can be overcome by combining NP‐centered strategies with fragment‐
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::be1f36eb2f87b0a1ff40e0a0e64c39ed
https://eprints.whiterose.ac.uk/151777/1/anie.201909518.pdf
https://eprints.whiterose.ac.uk/151777/1/anie.201909518.pdf
Autor:
Längle D; Department of Pharmaceutical & Medicinal Chemistry, Christian-Albrechts-University of Kiel, Gutenbergstrasse 76, 24118 Kiel, Germany., Wojtowicz-Piotrowski S; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London N6A 5C1, ON, Canada., Priegann T; Department of Pharmaceutical & Medicinal Chemistry, Christian-Albrechts-University of Kiel, Gutenbergstrasse 76, 24118 Kiel, Germany., Keller N; Department of Pharmaceutical & Medicinal Chemistry, Christian-Albrechts-University of Kiel, Gutenbergstrasse 76, 24118 Kiel, Germany., Wesseler F; Department of Pharmaceutical & Medicinal Chemistry, Christian-Albrechts-University of Kiel, Gutenbergstrasse 76, 24118 Kiel, Germany.; Faculty of Chemistry and Chemical Biology, Technical University Dortmund, Otto-Hahn-Strasse 6, 44227 Dortmund, Germany., Reckzeh ES; Faculty of Chemistry and Chemical Biology, Technical University Dortmund, Otto-Hahn-Strasse 6, 44227 Dortmund, Germany., Steffens K; Department of Pharmaceutical & Medicinal Chemistry, Christian-Albrechts-University of Kiel, Gutenbergstrasse 76, 24118 Kiel, Germany., Grathwol C; Institute of Pharmacy, University of Greifswald, Friedrich-Ludwig-Jahn-Strasse 17, 17489 Greifswald, Germany., Lemke J; Institute of Pharmacy, University of Greifswald, Friedrich-Ludwig-Jahn-Strasse 17, 17489 Greifswald, Germany., Flasshoff M; Faculty of Chemistry and Chemical Biology, Technical University Dortmund, Otto-Hahn-Strasse 6, 44227 Dortmund, Germany., Näther C; Institute of Inorganic Chemistry, Christian-Albrechts-University of Kiel, Max-Eyth-Straße 2, 24118 Kiel, Germany., Jonson AC; Early Chemical Development, Pharmaceutical Sciences, IMED Biotech Unit, AstraZeneca Gothenburg, Mölndal SE-43183, Sweden., Link A; Institute of Pharmacy, University of Greifswald, Friedrich-Ludwig-Jahn-Strasse 17, 17489 Greifswald, Germany., Koch O; Faculty of Chemistry and Chemical Biology, Technical University Dortmund, Otto-Hahn-Strasse 6, 44227 Dortmund, Germany.; Institute of Pharmaceutical and Medicinal Chemistry and German Center of Infection Research, Münster 48149, Germany., Di Guglielmo GM; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London N6A 5C1, ON, Canada., Schade D; Department of Pharmaceutical & Medicinal Chemistry, Christian-Albrechts-University of Kiel, Gutenbergstrasse 76, 24118 Kiel, Germany.; Partner Site Kiel, DZHK, German Center for Cardiovascular Research, 24105 Kiel, Germany.
Publikováno v:
ACS pharmacology & translational science [ACS Pharmacol Transl Sci] 2024 Mar 21; Vol. 7 (4), pp. 1069-1085. Date of Electronic Publication: 2024 Mar 21 (Print Publication: 2024).
Autor:
Wang Z; Woo Center for Big Data and Precision Health, Pratt School of Engineering, Duke University, Durham, NC, USA., Boretto M; Oncode, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center (UMC) Utrecht, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands., Millen R; Oncode, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center (UMC) Utrecht, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands., Natesh N; Department of Biomedical Engineering, Pratt School of Engineering, Duke University, Durham, NC, USA., Reckzeh ES; Oncode, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center (UMC) Utrecht, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands., Hsu C; College of Arts and Sciences, University of Chapel Hill, Chapel Hill, NC, USA., Negrete M; Department of Biomedical Engineering, Pratt School of Engineering, Duke University, Durham, NC, USA., Yao H; Biology Department, Trinity School of Arts and Sciences, Duke University, Durham, NC, USA., Quayle W; Xilis, Inc., Durham, NC, USA., Heaton BE; Department of Molecular Genetics and Microbiology, School of Medicine, Duke University, Durham, NC, USA., Harding AT; Department of Molecular Genetics and Microbiology, School of Medicine, Duke University, Durham, NC, USA., Bose S; Department of Biomedical Engineering, Pratt School of Engineering, Duke University, Durham, NC, USA., Driehuis E; Oncode, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center (UMC) Utrecht, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands., Beumer J; Oncode, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center (UMC) Utrecht, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands., Rivera GO; Department of Biomedical Engineering, Pratt School of Engineering, Duke University, Durham, NC, USA., van Ineveld RL; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 Utrecht, the Netherlands; Cancer Genomics Netherlands, Oncode Institute, 3584 Utrecht, the Netherlands., Gex D; Xilis, Inc., Durham, NC, USA., DeVilla J; Xilis, Inc., Durham, NC, USA., Wang D; Oncode, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center (UMC) Utrecht, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands., Puschhof J; Oncode, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center (UMC) Utrecht, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands; Microbiome and Cancer Division, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany., Geurts MH; Oncode, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center (UMC) Utrecht, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands., Yeung A; Department of Biomedical Engineering, Pratt School of Engineering, Duke University, Durham, NC, USA., Hamele C; Department of Molecular Genetics and Microbiology, School of Medicine, Duke University, Durham, NC, USA., Smith A; Xilis, Inc., Durham, NC, USA., Bankaitis E; Xilis, Inc., Durham, NC, USA., Xiang K; Department of Biomedical Engineering, Pratt School of Engineering, Duke University, Durham, NC, USA., Ding S; Department of Biomedical Engineering, Pratt School of Engineering, Duke University, Durham, NC, USA; Xilis, Inc., Durham, NC, USA., Nelson D; Xilis, Inc., Durham, NC, USA., Delubac D; Xilis, Inc., Durham, NC, USA., Rios A; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 Utrecht, the Netherlands., Abi-Hachem R; Department of Head and Neck Surgery and Communication Sciences, School of Medicine, Duke University, Durham, NC, USA., Jang D; Department of Head and Neck Surgery and Communication Sciences, School of Medicine, Duke University, Durham, NC, USA., Goldstein BJ; Department of Head and Neck Surgery and Communication Sciences, School of Medicine, Duke University, Durham, NC, USA., Glass C; Department of Pathology, School of Medicine, Duke University, Durham, NC, USA., Heaton NS; Department of Molecular Genetics and Microbiology, School of Medicine, Duke University, Durham, NC, USA., Hsu D; Division of Medical Oncology, Duke Cancer Institute, Duke University, Durham, NC, USA. Electronic address: shiaowen.hsu@duke.edu., Clevers H; Oncode, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center (UMC) Utrecht, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 Utrecht, the Netherlands. Electronic address: h.clevers@hubrecht.eu., Shen X; Woo Center for Big Data and Precision Health, Pratt School of Engineering, Duke University, Durham, NC, USA; Department of Biomedical Engineering, Pratt School of Engineering, Duke University, Durham, NC, USA; Terasaki Institute, Los Angeles, CA, USA. Electronic address: xiling.shen@terasaki.org.
Publikováno v:
Stem cell reports [Stem Cell Reports] 2022 Sep 13; Vol. 17 (9), pp. 1959-1975. Date of Electronic Publication: 2022 Aug 18.
Autor:
Reckzeh ES; Department of Chemical Biology Max Planck Institute of Molecular Physiology Otto-Hahn-Str. 11 44227 Dortmund Germany.; Department Chemistry and Chemical Biology TU Dortmund University Otto-Hahn-Str. 4a 44227 Dortmund Germany., Waldmann H; Department of Chemical Biology Max Planck Institute of Molecular Physiology Otto-Hahn-Str. 11 44227 Dortmund Germany.; Department Chemistry and Chemical Biology TU Dortmund University Otto-Hahn-Str. 4a 44227 Dortmund Germany.
Publikováno v:
European journal of organic chemistry [European J Org Chem] 2020 May 03; Vol. 2020 (16), pp. 2321-2329. Date of Electronic Publication: 2019 Nov 28.
Autor:
Reckzeh ES; Department Chemical Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany.; Department Chemistry and Chemical Biology, TU Dortmund University, Otto-Hahn-Strasse 4a, 44227, Dortmund, Germany., Waldmann H; Department Chemical Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany.; Department Chemistry and Chemical Biology, TU Dortmund University, Otto-Hahn-Strasse 4a, 44227, Dortmund, Germany.
Publikováno v:
Chembiochem : a European journal of chemical biology [Chembiochem] 2020 Jan 15; Vol. 21 (1-2), pp. 45-52. Date of Electronic Publication: 2019 Nov 08.
Autor:
Ceballos J; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany.; Current address: Laboratory of Catalysis and Organic Synthesis, EPFL SB ISIC LCSO, BCH 4221, 1015, Lausanne, Switzerland., Schwalfenberg M; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany., Karageorgis G; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany.; Current address: School of Chemistry, University of Leeds, Leeds, LS2 9JT, UK., Reckzeh ES; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany.; Faculty of Chemistry and Chemical Biology, Technical University Dortmund, Otto-Hahn-Strasse 6, 44227, Dortmund, Germany., Sievers S; Compound Management and Screening Center, Dortmund, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany., Ostermann C; Compound Management and Screening Center, Dortmund, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany., Pahl A; Compound Management and Screening Center, Dortmund, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany., Sellstedt M; Department of Chemistry, Umeå University, 901 87, Umeå, Sweden.; Current address: Clinical Chemistry, Laboratory Medicine, University Hospital of Umeå, 901 85, Umeå, Sweden., Nowacki J; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany., Carnero Corrales MA; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany., Wilke J; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany.; Faculty of Chemistry and Chemical Biology, Technical University Dortmund, Otto-Hahn-Strasse 6, 44227, Dortmund, Germany., Laraia L; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany.; Current address: Department of Chemistry, Technical University of Denmark, Kemitorvet, Bygning 207, 2800, Kgs Lyngby, Denmark., Tschapalda K; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany., Metz M; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany., Sehr DA; Department of Molecular Cell Biology, Institute of Biochemistry and Pathobiochemistry, Ruhr University Bochum, 44801, Bochum, Germany., Brand S; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany., Winklhofer K; Department of Molecular Cell Biology, Institute of Biochemistry and Pathobiochemistry, Ruhr University Bochum, 44801, Bochum, Germany., Janning P; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany., Ziegler S; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany., Waldmann H; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany.; Faculty of Chemistry and Chemical Biology, Technical University Dortmund, Otto-Hahn-Strasse 6, 44227, Dortmund, Germany.
Publikováno v:
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2019 Nov 18; Vol. 58 (47), pp. 17016-17025. Date of Electronic Publication: 2019 Oct 07.
Autor:
Reckzeh ES; Max Planck Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany; Technical University Dortmund, Faculty of Chemistry and Chemical Biology, Otto-Hahn-Strasse 6, 44227 Dortmund, Germany., Karageorgis G; Max Planck Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany., Schwalfenberg M; Max Planck Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany., Ceballos J; Max Planck Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany., Nowacki J; Max Planck Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany., Stroet MCM; Max Planck Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany., Binici A; Max Planck Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany., Knauer L; Technical University Dortmund, Faculty of Chemistry and Chemical Biology, Otto-Hahn-Strasse 6, 44227 Dortmund, Germany., Brand S; Max Planck Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany., Choidas A; Lead Discovery Center GmbH, Otto-Hahn-Strasse 15, 44227 Dortmund, Germany., Strohmann C; Technical University Dortmund, Faculty of Chemistry and Chemical Biology, Otto-Hahn-Strasse 6, 44227 Dortmund, Germany., Ziegler S; Max Planck Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany., Waldmann H; Max Planck Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany; Technical University Dortmund, Faculty of Chemistry and Chemical Biology, Otto-Hahn-Strasse 6, 44227 Dortmund, Germany. Electronic address: herbert.waldmann@mpi-dortmund.mpg.de.
Publikováno v:
Cell chemical biology [Cell Chem Biol] 2019 Sep 19; Vol. 26 (9), pp. 1214-1228.e25. Date of Electronic Publication: 2019 Jul 11.
Autor:
Reckzeh ES; Department of Chemical Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany., Brockmeyer A; Department of Chemical Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany., Metz M; Department of Chemical Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany., Waldmann H; Department of Chemical Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany., Janning P; Department of Chemical Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany. petra.janning@mpi-dortmund.mpg.de.
Publikováno v:
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2019; Vol. 1888, pp. 73-98.
Autor:
Karageorgis G; Max-Planck-Institut für Molekulare Physiologie, Abt. Chemische Biologie, Dortmund, Germany., Reckzeh ES; Max-Planck-Institut für Molekulare Physiologie, Abt. Chemische Biologie, Dortmund, Germany.; Technische Universität Dortmund, Fakultät Chemie, Lehrbereich Chemische Biologie, Dortmund, Germany., Ceballos J; Max-Planck-Institut für Molekulare Physiologie, Abt. Chemische Biologie, Dortmund, Germany.; Technische Universität Dortmund, Fakultät Chemie, Lehrbereich Chemische Biologie, Dortmund, Germany., Schwalfenberg M; Max-Planck-Institut für Molekulare Physiologie, Abt. Chemische Biologie, Dortmund, Germany.; Technische Universität Dortmund, Fakultät Chemie, Lehrbereich Chemische Biologie, Dortmund, Germany., Sievers S; Max-Planck-Institut für Molekulare Physiologie, Abt. Chemische Biologie, Dortmund, Germany.; Compound Management and Screening Center, Dortmund, Germany., Ostermann C; Max-Planck-Institut für Molekulare Physiologie, Abt. Chemische Biologie, Dortmund, Germany.; Compound Management and Screening Center, Dortmund, Germany., Pahl A; Max-Planck-Institut für Molekulare Physiologie, Abt. Chemische Biologie, Dortmund, Germany.; Compound Management and Screening Center, Dortmund, Germany., Ziegler S; Max-Planck-Institut für Molekulare Physiologie, Abt. Chemische Biologie, Dortmund, Germany., Waldmann H; Max-Planck-Institut für Molekulare Physiologie, Abt. Chemische Biologie, Dortmund, Germany. herbert.waldmann@mpi-dortmund.mpg.de.; Technische Universität Dortmund, Fakultät Chemie, Lehrbereich Chemische Biologie, Dortmund, Germany. herbert.waldmann@mpi-dortmund.mpg.de.
Publikováno v:
Nature chemistry [Nat Chem] 2018 Nov; Vol. 10 (11), pp. 1103-1111. Date of Electronic Publication: 2018 Sep 10.