m 6 A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation

Autor: Geula, Shay, Moshitch-Moshkovitz, Sharon, Dominissini, Dan, Mansour, Abed AlFatah, Kol, Nitzan, Salmon-Divon, Mali, Hershkovitz, Vera, Peer, Eyal, Mor, Nofar, Manor, Yair S., Ben-Haim, Moshe Shay, Eyal, Eran, Yunger, Sharon, Pinto, Yishay, Jaitin, Diego Adhemar, Viukov, Sergey, Rais, Yoach, Krupalnik, Vladislav, Chomsky, Elad, Zerbib, Mirie, Maza, Itay, Rechavi, Yoav, Massarwa, Rada, Hanna, Suhair, Amit, Ido, Levanon, Erez Y., Amariglio, Ninette, Stern-Ginossar, Noam, Novershtern, Noa, Rechavi, Gideon, Hanna, Jacob H.

Publikováno v: Science, 2015 Feb . 347(6225), 1002-1006.

Externí odkaz: http://www.jstor.org/stable/24746225

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Stem cells. m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation.

Autor: Geula S; The Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel., Moshitch-Moshkovitz S; Cancer Research Center, Chaim Sheba Medical Center, Tel Hashomer, Israel, and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel., Dominissini D; Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL 60637, USA., Mansour AA; The Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel., Kol N; Cancer Research Center, Chaim Sheba Medical Center, Tel Hashomer, Israel, and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel., Salmon-Divon M; Cancer Research Center, Chaim Sheba Medical Center, Tel Hashomer, Israel, and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel., Hershkovitz V; Cancer Research Center, Chaim Sheba Medical Center, Tel Hashomer, Israel, and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel., Peer E; Cancer Research Center, Chaim Sheba Medical Center, Tel Hashomer, Israel, and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel., Mor N; The Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel., Manor YS; The Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel., Ben-Haim MS; Cancer Research Center, Chaim Sheba Medical Center, Tel Hashomer, Israel, and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel., Eyal E; Cancer Research Center, Chaim Sheba Medical Center, Tel Hashomer, Israel, and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel., Yunger S; Cancer Research Center, Chaim Sheba Medical Center, Tel Hashomer, Israel, and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel., Pinto Y; Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat Gan, Israel., Jaitin DA; The Department of Immunology, Weizmann Institute of Science, Rehovot, Israel., Viukov S; The Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel., Rais Y; The Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel., Krupalnik V; The Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel., Chomsky E; The Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel., Zerbib M; The Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel., Maza I; The Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel., Rechavi Y; The Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel., Massarwa R; The Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel., Hanna S; The Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel. The Department of Pediatrics and the Pediatric Immunology Unit, Rambam Medical Center, and the B. Rappaport Faculty of Medicine, Technion, Haifa, Israel., Amit I; The Department of Immunology, Weizmann Institute of Science, Rehovot, Israel., Levanon EY; Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat Gan, Israel., Amariglio N; Cancer Research Center, Chaim Sheba Medical Center, Tel Hashomer, Israel, and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat Gan, Israel., Stern-Ginossar N; The Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel., Novershtern N; The Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel. jacob.hanna@weizmann.ac.il noa.novershtern@weizmann.ac.il gidi.rechavi@sheba.health.gov.il., Rechavi G; Cancer Research Center, Chaim Sheba Medical Center, Tel Hashomer, Israel, and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. jacob.hanna@weizmann.ac.il noa.novershtern@weizmann.ac.il gidi.rechavi@sheba.health.gov.il., Hanna JH; The Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel. jacob.hanna@weizmann.ac.il noa.novershtern@weizmann.ac.il gidi.rechavi@sheba.health.gov.il.

Publikováno v: Science (New York, N.Y.) [Science] 2015 Feb 27; Vol. 347 (6225), pp. 1002-6. Date of Electronic Publication: 2015 Jan 01.