Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Receptors de neurotransmissors"'
Autor:
Ana Santos-Gómez, Adrián García-Recio, Federico Miguez-Cabello, David Soto, Xavier Altafaj, Mireia Olivella
Publikováno v:
Frontiers in Cellular Neuroscience. 16
The clinical spectrum of GRIN-related neurodevelopmental disorders (GRD) results from gene- and variant-dependent primary alterations of the NMDA receptor, disturbing glutamatergic neurotransmission. Despite GRIN gene variants’ functional annotatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc4a807f2d5258b458a5cbc758bff0d5
https://doi.org/10.3389/fncel.2022.998719
https://doi.org/10.3389/fncel.2022.998719
Autor:
Marija Radosevic, Jesús Planagumà, Francesco Mannara, Araceli Mellado, Esther Aguilar, Lidia Sabater, Jon Landa, Anna García-Serra, Estibaliz Maudes, Xavier Gasull, Mike Lewis, Josep Dalmau
Publikováno v:
Neurology® Neuroimmunology & Neuroinflammation
article-version (Version of Record) 3
Dipòsit Digital de la UB
Universidad de Barcelona
article-version (Version of Record) 3
Dipòsit Digital de la UB
Universidad de Barcelona
Background and ObjectivesTo demonstrate that an analog (SGE-301) of a brain-derived cholesterol metabolite, 24(S)-hydroxycholesterol, which is a selective positive allosteric modulator (PAM) of NMDA receptors (NMDARs), is able to reverse the memory a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::789bc9b5e3ea2039c2648c29878136ed
http://europepmc.org/articles/PMC8669659
http://europepmc.org/articles/PMC8669659
Autor:
Panarello, Silvia
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
TDX (Tesis Doctorals en Xarxa)
TDR. Tesis Doctorales en Red
instname
Universidad de Barcelona
TDX (Tesis Doctorals en Xarxa)
TDR. Tesis Doctorales en Red
instname
[eng] Photopharmacology has the main purpose to allow the control of protein activity with light. The most exploited strategy used to achieve this objective is the freely diffusible photopharmacology and it is based in the use of photosensitive ligan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::431e522d2be08ae4a554b634673f1957
http://hdl.handle.net/2445/181968
http://hdl.handle.net/2445/181968
Autor:
Vasilopoulou, Foteini
Publikováno v:
TDX (Tesis Doctorals en Xarxa)
TDR. Tesis Doctorales en Red
instname
Dipòsit Digital de la UB
Universidad de Barcelona
TDR. Tesis Doctorales en Red
instname
Dipòsit Digital de la UB
Universidad de Barcelona
[eng] The identification of imidazoline receptors (IR) as a novel class of receptors has posed manifold research questions regarding their pharmacological and potential therapeutic properties. Among them, I2-IR receptors are widely distributed in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::133a7ffd0139efc73b310138a94a335f
http://hdl.handle.net/10803/674236
http://hdl.handle.net/10803/674236
Autor:
Gómez-Santacana, Xavier, Dalton, James, Rovira, Xavier, Pin, Jean-Philippe, Goudet, Cyril, Gorostiza, Pau, Giraldo, Jesús, Llebaria, Amadeu, Dalton, James A.R.
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2017, 127, pp.567-576. ⟨10.1016/j.ejmech.2017.01.013⟩
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2017, 127, pp.567-576. ⟨10.1016/j.ejmech.2017.01.013⟩
International audience; Modulation of metabotropic glutamate receptor 5 (mGlu5) with partial allosteric antagonists has received increased interest due to their favourable in vivo activity profiles compared to the unfavourable side-effects of full in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9068821ac50dee1bb803ee3a5a70f14c
https://doi.org/10.1016/j.ejmech.2017.01.013
https://doi.org/10.1016/j.ejmech.2017.01.013
Autor:
James J. Doherty, Xavier Gasull, Marija Radosevic, Estibaliz Maudes, Mike Lewis, Jesús Planagumà, Anna García-Serra, Marta Pedreño, Jing Dai, Francesco Mannara, David Soto, Esther Aguilar, Michael Quirk, Josep Dalmau, Steven M. Paul
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
Anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis is an immune-mediated disease characterized by a complex neuropsychiatric syndrome in association with an antibody-mediated decrease of NMDAR. About 85% of patients respond to immunotherapy (and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::843bc8c547c99a480b98c2d041fa625d
https://pubmed.ncbi.nlm.nih.gov/32830245
https://pubmed.ncbi.nlm.nih.gov/32830245
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Neural Regeneration Research
Neural Regeneration Research, Vol 14, Iss 11, Pp 1912-1914 (2019)
Universidad de Barcelona
Neural Regeneration Research
Neural Regeneration Research, Vol 14, Iss 11, Pp 1912-1914 (2019)
G protein-coupled receptor 37 (GPR37), also known as parkin associated endothelin-like (Pael) receptor, is an orphan G protein-coupled receptor, which suffers a defective parking ubiquitination in autosomal recessive Parkinson's disease promoting its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d76c30a062bc5840e0ec470514d01bea
http://hdl.handle.net/2445/155077
http://hdl.handle.net/2445/155077
Autor:
Girish Vajramani, Chrysia-Maria Pegasiou, Steven D. Houghton, Ksenia Kurbatskaya, Mariana Vargas-Caballero, Xavier Altafaj, Diederik Bulters, Aminul I. Ahmed, Paul Grundy, Hanna Kariis, Hannah Warming, Aleksandra P. Pitera, Katrin Deinhardt
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Molecular Brain
Molecular Brain, Vol 12, Iss 1, Pp 1-8 (2019)
Universidad de Barcelona
Molecular Brain
Molecular Brain, Vol 12, Iss 1, Pp 1-8 (2019)
Glutamate receptors of the N-methyl-D-aspartate (NMDA) family are coincident detectors of pre- and postsynaptic activity, allowing Ca2+ influx into neurons. These properties are central to neurological disease mechanisms and are proposed to be the ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f02353a8b3e6399636af977b8577cc3
https://eprints.soton.ac.uk/432715/
https://eprints.soton.ac.uk/432715/
Autor:
Ramos-Vicente, David, Ji, Jie, Gratacòs-Batlle, Esther, Gou Alsina, Gemma, Reig-Viader, R., Fernandez-Martín, josé Luis, Burguera, Demian, Navas-Pérez, Enrique, García-Fernández, Jordi, Fuentes-Prior, Pablo, Escrivà, Hector, Roher Armentia, Nerea, Soto, David, Bayés, Àlex, Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina \\'Vicent Villar Palasí\\'
Publikováno v:
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
eLife
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
eLife, Vol 7 (2018)
Dipòsit Digital de la UB
Universidad de Barcelona
Universitat Autònoma de Barcelona
eLife
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
eLife, Vol 7 (2018)
Dipòsit Digital de la UB
Universidad de Barcelona
Glutamate receptors are divided in two unrelated families: ionotropic (iGluR), driving synaptic transmission, and metabotropic (mGluR), which modulate synaptic strength. The present classification of GluRs is based on vertebrate proteins and has rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19d9063caf6bf50d44bd68cd159a7973
https://ddd.uab.cat/record/253730
https://ddd.uab.cat/record/253730
Autor:
Esther Gratacòs-Batlle, Mireia Olivella, Nuria Sánchez-Fernández, Natalia Yefimenko, Federico Miguez-Cabello, Rut Fadó, Núria Casals, Xavier Gasull, Santiago Ambrosio, David Soto
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Frontiers in Molecular Neuroscience
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Frontiers in Molecular Neuroscience
In neurons, AMPA receptor (AMPAR) function depends essentially on their constituent components: the ion channel forming subunits and ion channel associated proteins. On the other hand, AMPAR trafficking is tightly regulated by a vast number of intrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15f69c3193da91feadbf94493be1f780
http://hdl.handle.net/2445/146517
http://hdl.handle.net/2445/146517